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AB18280

APC Anti-CD4 antibody [MEM-241]

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(2 제품이 사용된 논문 )

Anti-CD4 antibody [MEM-241] conjugated to APC - suitable for flow cytometry, and reacts with human samples. Clone [MEM-241] is a mouse monoclonal antibody cited in 8 publications.

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Flow Cytometry - APC Anti-CD4 antibody [MEM-241] (AB18280)
  • Flow Cyt

Unknown

Flow Cytometry - APC Anti-CD4 antibody [MEM-241] (AB18280)

Overlay histogram showing peripheral blood lymphocytes stained with ab18280 (red line). The cells were incubated with the antibody (ab18280, 1/20 dilution) for 30 min at 4°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 2μg/1x106 cells) with secondary antibody DyLight® 649 goat anti-mouse IgG (H&L) (ab96882) at 1/200 dilution for 30 min at 4°C. Acquisition of >5,000 events was performed gating on peripheral blood lymphocytes.

Flow Cytometry - APC Anti-CD4 antibody [MEM-241] (AB18280)
  • Flow Cyt

Unknown

Flow Cytometry - APC Anti-CD4 antibody [MEM-241] (AB18280)

Surface staining of human peripheral blood cells with anti-human CD4 (MEM-241) APC.

관련 conjugated 항체와 다양한 조성의 항체 (7)

  • 785 APC/Cy7®

    APC/Cy7® Anti-CD4 antibody [MEM-241]

  • 723 Alexa Fluor® 700

    Alexa Fluor® 700 Anti-CD4 antibody [MEM-241]

  • Biotin

    Biotin Anti-CD4 antibody [MEM-241]

  • 519 FITC

    FITC Anti-CD4 antibody [MEM-241]

  • 578 PE

    PE Anti-CD4 antibody [MEM-241]

  • 778 PE/Cy7®

    PE/Cy7® Anti-CD4 antibody [MEM-241]

  • 675 PerCP

    PerCP Anti-CD4 antibody [MEM-241]

주요 정보

Host species

Mouse

Clonality

Monoclonal

Clone number

MEM-241

Isotype

IgG1

Light chain 타입

kappa

Conjugation

APC

Excitation/Emission

Ex: 650nm, Em: 660nm

Carrier free

No

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Recombinant Fragment Protein within Human CD4. The exact immunogen used to generate this antibody is proprietary information.

P01730

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1/20", "FlowCyt-species-notes": "<p><a href='/ko/products/primary-antibodies/apc-mouse-fab2-igg1-kappa-monoclonal-15h6-isotype-control-ab37391'>ab37391</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.</p>" } } }

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
pH: 7.4 Preservative: 0.097% Sodium azide Constituents: BSA, PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

타겟 정보

Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule : peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages.. (Microbial infection) Primary receptor for human immunodeficiency virus-1 (HIV-1) (PubMed : 12089508, PubMed : 16331979, PubMed : 2214026, PubMed : 9641677). Down-regulated by HIV-1 Vpu (PubMed : 17346169). Acts as a receptor for Human Herpes virus 7/HHV-7 (PubMed : 7909607).
See full target information CD4

대체 명칭 보기

CD4, T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3

제품이 사용된 논문 (2)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Tissue engineering and regenerative medicine 21:609-624 PubMed38568409

2024

Effects of Mesenchymal Stem Cells-Derived Extracellular Vesicles on Inhibition of Hepatic Fibrosis by Delivering miR-200a.

Applications

Unspecified application

Species

Unspecified reactive species

Ai-Lei Xu,Long Han,Jun Yan,Dan Liu,Wei Wang

Cancer cell international 21:58 PubMed33468159

2021

IRF4 overexpression promotes the transdifferentiation of tregs into macrophage-like cells to inhibit the development of colon cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Jiwei Wang,Song Li,Honglang Li,Xiaoshuang Zhou,Huabin Wen,Bin Lai
제품이 사용된 논문 모두 보기

Product promise

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