JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB239306

APC/Cy7® Anti-CD9 antibody [MEM-61]

Be the first to review this product! 리뷰 제출

|

(0 출판물)

Anti-CD9 antibody [MEM-61] conjugated to APC/Cy7® - suitable for flow cytometry, and reacts with human samples. Clone [MEM-61] is a mouse monoclonal antibody cited in 22 publications.

Design your panel with our interactive flow cytometry panel builder. Click here.
1 이미지
Flow Cytometry - APC/Cy7® Anti-CD9 antibody [MEM-61] (AB239306)
  • Flow Cyt

Supplier Data

Flow Cytometry - APC/Cy7® Anti-CD9 antibody [MEM-61] (AB239306)

Flow Cytometry analysis of human peripheral blood labeling CD9 with ab239306. Surface staining.

관련 conjugated 항체와 다양한 조성의 항체 (4)

  • 660 APC

    APC Anti-CD9 antibody [MEM-61]

  • 665 Alexa Fluor® 647

    Alexa Fluor® 647 Anti-CD9 antibody [MEM-61]

  • Biotin

    Biotin Anti-CD9 antibody [MEM-61]

  • 519 FITC

    FITC Anti-CD9 antibody [MEM-61]

주요 정보

Host species

Mouse

Clonality

Monoclonal

Clone number

MEM-61

Isotype

IgG1

Light chain 타입

kappa

Conjugation

APC/Cy7®

Excitation/Emission

Ex: 650nm, Em: 785nm

Carrier free

No

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing CD9 protein. The exact immunogen used to generate this antibody is proprietary information.

P21926

style
left-column

대체품

Primary Antibodies

AB2215

Anti-CD9 antibody [MEM-61]

BOND RX™ Validated|Advanced Validation

Mass Cytometry - Anti-CD9 antibody [MEM-61] (AB2215)

  • 4
  • 4
Primary Antibodies

AB223052

Anti-CD9 antibody

BOND RX™ Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD9 antibody (AB223052)

  • 0
  • 0
Primary Antibodies

AB82390

Anti-CD9 antibody [EM-04]

Western blot - Anti-CD9 antibody [EM-04] (AB82390)

  • 3
  • 1

보완 제품

Primary Antibodies

AB283757

PE Anti-CD81 antibody [EPR21916]

RabMAb|Recombinant

Flow Cytometry - PE Anti-CD81 antibody [EPR21916] (AB283757)

  • 0
  • 0
Primary Antibodies

AB318246

Alexa Fluor® 488 Anti-CD63 antibody [KILL150A]

Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Alexa Fluor® 488 Anti-CD63 antibody [KILL150A] (AB318246)

  • 0
  • 0
Primary Antibodies

AB200315

Alexa Fluor® 488 Anti-CD45 antibody [EP322Y]

RabMAb|Recombinant

Flow Cytometry (Intracellular) - Alexa Fluor® 488 Anti-CD45 antibody [EP322Y] (AB200315)

  • 0
  • 0
Primary Antibodies

AB196515

Alexa Fluor® 647 Anti-CD19 antibody [EPR5906]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Alexa Fluor® 647 Anti-CD19 antibody [EPR5906] (AB196515)

  • 5
  • 1
style
left-column

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "4 µL for 10^5 Cells", "FlowCyt-species-notes": "<p>OR 100 μl of whole blood.</p>" } } }
style
left-column

제품 세부 정보

This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5, 268, 486 and related patents. Cy® and CyDye® are trademarks of Cytiva.
style
left-column

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Size-exclusion chromatography
Purification 관련 사항
The purified antibody is conjugated with tandem dye APC-Cy™7 under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
보관 버퍼
pH: 7.4 Preservative: 0.0975% Sodium azide Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
보관 정보
Store in the dark
style
left-column

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

CD9 also known as motility-related protein-1 (MRP-1) is a transmembrane glycoprotein with a molecular weight of approximately 24 kDa. This protein is part of the tetraspanin family and shows widespread expression throughout different tissues including hematopoietic and non-hematopoietic cells. CD9 participates in numerous cellular processes by interacting with integrins and other cell surface receptors facilitating the organization of molecular complexes within the cell membrane.
Biological function summary

The CD9 protein is integral to cell adhesion migration and fusion. It forms complexes with other tetraspanins and proteins like EWI-2 and EWI-F contributing to cellular signaling and membrane compartmentalization. Additionally CD9 plays an important role in the formation and secretion of exosomes tiny vesicles emitted by cells that mediate cell-to-cell communication. These exosomes can be analyzed using tools like exosome assays and detection kits that target CD9 proteins.

Pathways

CD9 is involved in the regulation of immune response and cell morphology. It participates in pathways such as the integrin signaling pathway and the phosphatidylinositol 3-kinase (PI3K) signaling pathway. CD9 modulates these interactions by associating with proteins such as integrins and other members of the tetraspanin family influencing cellular movement and proliferation.

CD9 has connections to various conditions including cancer and infectious diseases. In cancer CD9 can influence tumor progression and metastasis while its altered expression levels have been associated with different cancer types. CD9 interacts with proteins such as integrins and CD81 in these contexts affecting cellular adhesion and migration mechanisms. In infectious diseases CD9 is involved in viral entry processes as some viruses utilize CD9 and its associated tetraspanins for entry into host cells.
style
left-column
style
left-column

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

타겟 정보

Integral membrane protein associated with integrins, which regulates different processes, such as sperm-egg fusion, platelet activation and aggregation, and cell adhesion (PubMed : 14575715, PubMed : 18541721, PubMed : 8478605). Present at the cell surface of oocytes and plays a key role in sperm-egg fusion, possibly by organizing multiprotein complexes and the morphology of the membrane required for the fusion (By similarity). In myoblasts, associates with CD81 and PTGFRN and inhibits myotube fusion during muscle regeneration (By similarity). In macrophages, associates with CD81 and beta-1 and beta-2 integrins, and prevents macrophage fusion into multinucleated giant cells specialized in ingesting complement-opsonized large particles (PubMed : 12796480). Also prevents the fusion between mononuclear cell progenitors into osteoclasts in charge of bone resorption (By similarity). Acts as a receptor for PSG17 (By similarity). Involved in platelet activation and aggregation (PubMed : 18541721). Regulates paranodal junction formation (By similarity). Involved in cell adhesion, cell motility and tumor metastasis (PubMed : 7511626, PubMed : 8478605).
See full target information CD9

대체 명칭 보기

CD9, MIC3, TSPAN29, GIG2, CD9 antigen, 5H9 antigen, Cell growth-inhibiting gene 2 protein, Leukocyte antigen MIC3, Motility-related protein, Tetraspanin-29, p24, MRP-1, Tspan-29
style
left-column
style
left-column
style
right-column

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com