AB275710
Anti-PECAM1 antibody [14] conjugated to APC - suitable for flow cytometry, and reacts with human samples. Clone [14] is a mouse monoclonal antibody cited in 3 publications.
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1 이미지
![Flow Cytometry - APC Anti-PECAM1 antibody [14] (AB275710)](https://content.abcam.com/products/images/apc-pecam1-antibody-14-ab275710--flow-cytometry-img50358.jpg/_jcr_content/renditions/webp-768.webp)
- Flow Cyt
Supplier Data
Flow Cytometry - APC Anti-PECAM1 antibody [14] (AB275710)
Flow cytometric analysis of human whole blood monocytes labeling PECAM1 with ab275710 (Black) compared with isotype control (Grey). The fluorescence histograms were derived from events with the forward and side light-scatter characteristics of viable monocytes.
보완 제품
![Flow Cytometry (Intracellular) - Alexa Fluor® 488 Anti-CD45 antibody [EP322Y] (AB200315)](https://content.abcam.com/products/images/alexa-fluor-488-cd45-antibody-ep322y-ab200315--flow-cytometry-intracellular-img79307.jpg)
![Flow Cytometry (Intracellular) - Alexa Fluor® 488 Anti-CD34 antibody [EP373Y] (AB195013)](https://content.abcam.com/products/images/alexa-fluor-488-cd34-antibody-ep373y-ab195013--flow-cytometry-intracellular-img26725.jpg)
Primary Antibodies
AB315961
Alexa Fluor® 488 Anti-CD90 / Thy1 antibody [EPR28145-53]
RabMAb|Recombinant
![Flow Cytometry - Alexa Fluor® 488 Anti-CD90 / Thy1 antibody [EPR28145-53] (AB315961)](https://content.abcam.com/products/images/alexa-fluor-488-cd90-thy1-antibody-epr28145-53-ab315961--flow-cytometry-img425312.jpg)
- 0
- 0
Primary Antibodies
AB302698
Alexa Fluor® 647 Anti-CD14 antibody [SP192]
BOND RX™ Validated|RabMAb|Recombinant
![Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Alexa Fluor® 647 Anti-CD14 antibody [SP192] (AB302698)](https://content.abcam.com/products/images/alexa-fluor-647-cd14-antibody-sp192-ab302698--immunohistochemistry-formalin-pfa-fixed-paraffin-embedded-sections-img402480.jpg)
- 0
- 0
Reactivity 정보
{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p>5 μL/Test</p>" } } }
특성 및 보관 정보
제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
Preservative: 0.09% Sodium azide Constituents: 0.5% BSA
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
보관 정보
Do Not Freeze|Store in the dark
제품 프로토콜
For this product, it's our understanding that no specific protocols are required. You can visit:
- Visit the General protocols
- Visit the Troubleshooting
타겟 정보
Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions (PubMed : 17580308, PubMed : 19342684). Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes (PubMed : 19342684). Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions (PubMed : 27958302). Heterophilic interaction with CD177 plays a role in transendothelial migration of neutrophils (PubMed : 17580308). Homophilic ligation of PECAM1 prevents macrophage-mediated phagocytosis of neighboring viable leukocytes by transmitting a detachment signal (PubMed : 12110892). Promotes macrophage-mediated phagocytosis of apoptotic leukocytes by tethering them to the phagocytic cells; PECAM1-mediated detachment signal appears to be disabled in apoptotic leukocytes (PubMed : 12110892). Modulates bradykinin receptor BDKRB2 activation (PubMed : 18672896). Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in endothelial cells (PubMed : 18672896). Induces susceptibility to atherosclerosis (By similarity).. Isoform Delta15. Does not protect against apoptosis.
대체 명칭 보기
CD31, Platelet endothelial cell adhesion molecule, PECAM-1, EndoCAM, GPIIA', PECA1, PECAM1
Product promise
저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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