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AB272341

APC Anti-Sialoadhesin/CD169 antibody [7-239]

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Anti-Sialoadhesin/CD169 antibody [7-239] conjugated to APC - suitable for flow cytometry, and reacts with human samples. Clone [7-239] is a mouse monoclonal antibody cited in 53 publications.

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Flow Cytometry - APC Anti-Sialoadhesin/CD169 antibody [7-239] (AB272341)
  • Flow Cyt

Supplier Data

Flow Cytometry - APC Anti-Sialoadhesin/CD169 antibody [7-239] (AB272341)

Flow cytometry multicolor surface staining of human TNF-α and INF-γ stimulated peripheral blood mononuclear cells stained using ab272341 at 10 μl reagent per milion cells in 100 μl of cell suspension and anti-human CD11c (BU15) FITC antibody (20 μl reagent / 100 μl of peripheral whole blood).

Flow Cytometry - APC Anti-Sialoadhesin/CD169 antibody [7-239] (AB272341)
  • Flow Cyt

Supplier Data

Flow Cytometry - APC Anti-Sialoadhesin/CD169 antibody [7-239] (AB272341)

Separation of human CD169 positive CD11c positive cells (red-filled) from CD169 negative CD11c negative cells (black-dashed) in flow cytometry analysis (surface staining) of human TNF-α and INF-γ stimulated peripheral blood mononuclear cells stained using ab272341 at 10 μl reagent per milion cells in 100 μl of cell suspension.

Flow Cytometry - APC Anti-Sialoadhesin/CD169 antibody [7-239] (AB272341)
  • Flow Cyt

Supplier Data

Flow Cytometry - APC Anti-Sialoadhesin/CD169 antibody [7-239] (AB272341)

Flow cytometry surface staining pattern of human TNF-α and INF-γ stimulated peripheral blood mononuclear cells stained using ab272341 at 10 μl reagent per milion cells in 100 μl of cell suspension.

관련 conjugated 항체와 다양한 조성의 항체 (2)

주요 정보

Host species

Mouse

Clonality

Monoclonal

Clone number

7-239

Isotype

IgG1

Conjugation

APC

Excitation/Emission

Ex: 650nm, Em: 660nm

Carrier free

No

Reacts with

Human

Applications

Flow Cyt

applications

Immunogen

Cell preparation containing SIGLEC1 protein. The exact immunogen used to generate this antibody is proprietary information.

Q9BZZ2

Epitope

Extracellular

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보완 제품

Assay Kits

AB213757

Human CD169 ELISA Kit (SIGLEC-1)

Sandwich ELISA - Human CD169 ELISA Kit (SIGLEC-1) (AB213757)

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Primary Antibodies

AB302698

Alexa Fluor® 647 Anti-CD14 antibody [SP192]

BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Alexa Fluor® 647 Anti-CD14 antibody [SP192] (AB302698)

  • 0
  • 0
Primary Antibodies

AB312914

Alexa Fluor® 594 Anti-CD11b antibody [M1/70]

Recombinant

Flow Cytometry - Alexa Fluor® 594 Anti-CD11b antibody [M1/70] (AB312914)

  • 0
  • 0
Primary Antibodies

AB313900

Alexa Fluor® 488 Anti-CD11c antibody [KB90]

Recombinant

Immunocytochemistry/ Immunofluorescence - Alexa Fluor® 488 Anti-CD11c antibody [KB90] (AB313900)

  • 0
  • 0
Primary Antibodies

AB24982

Cy5 ® Anti-CD45.1 antibody [A20]

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "<p>The reagent is designed for analysis of human blood cells using 10 μl reagent / 100 μl of whole blood or 10<sup>6</sup> cells in a suspension.</p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Size-exclusion chromatography
Purification 관련 사항
Purified from TCS.
보관 버퍼
pH: 7.4 Preservative: 0.0975% Sodium azide Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
보관 정보
Store in the dark
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells. Plays a crucial role in limiting bacterial dissemination by engaging sialylated bacteria to promote effective phagocytosis and antigen presentation for the adaptive immune response (PubMed : 12940982, PubMed : 33489013). Mediates the uptake of various enveloped viruses via sialic acid recognition and subsequently induces the formation of intracellular compartments filled with virions (VCCs) (PubMed : 28129379). In turn, enhances macrophage-to-T-cell transmission of several viruses including HIV-1 or SARS-CoV-2 (PubMed : 28129379, PubMed : 34782760). Acts as an endocytic receptor mediating clathrin dependent endocytosis. Preferentially binds to alpha-2,3-linked sialic acid (PubMed : 12940982). Binds to SPN/CD43 on T-cells (By similarity). May play a role in hemopoiesis. Plays a role in the inhibition of antiviral innate immune by promoting TBK1 degradation via TYROBP and TRIM27-mediated ubiquitination (PubMed : 26358190).. (Microbial infection) Facilitates viral cytoplasmic entry into activated dendritic cells via recognition of sialylated gangliosides pesent on viral membrane.
See full target information SIGLEC1

대체 명칭 보기

CD169, SN, SIGLEC1, Sialoadhesin, Sialic acid-binding Ig-like lectin 1, Siglec-1
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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