AB221453

Anti-APMAP antibody

Be the first to review this product! 리뷰 제출

(1 출판물)

Rabbit Polyclonal APMAP antibody. Suitable for ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human APMAP aa 150 to C-terminus.

대체 명칭 보기

C20orf3, UNQ1869/PRO4305, APMAP, Adipocyte plasma membrane-associated protein, Protein BSCv

1 이미지

Immunocytochemistry/ Immunofluorescence - Anti-APMAP antibody (AB221453)

ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-APMAP antibody (AB221453)

Immunofluorescent analysis of paraformaldehyde-fixed, Triton X-100 permeabilized U-2 OS cells labeling APMAP with ab221453 at 4 μg/mL dilution (green).

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human APMAP aa 150 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q9HDC9

style

left-column

style

left-column

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p>Fixation/Permeabilization: PFA/Triton X-100.</p>" }, "Mouse": { "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Cow": { "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

style

left-column

style

left-column

특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Immunogen

보관 버퍼

pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)

배송 시 보관 조건

Blue Ice

적절한 단기 보관 기간

1-2 weeks

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

style

left-column

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

APMAP also known as adipocyte plasma membrane-associated protein is an integral membrane protein that weighs approximately 45 kDa. APMAP localizes primarily in adipose tissues and hepatocytes. This protein resides within both the plasma membrane and intracellular compartments. APMAP participates in lipid metabolism through its interactions with various protein complexes. Its expression levels vary across different tissues reflecting a specialized role in certain physiological functions.

Biological function summary

APMAP functions within the modulation of lipid homeostasis especially in adipocytes. It shows involvement in triglyceride metabolism by regulating enzyme activity responsible for lipid turnover. APMAP acts as a part of a protein complex that includes enzymes affecting lipid storage and release. Through such interactions APMAP influences key biological processes that maintain lipid balance supporting energy homeostasis in mammals.

Pathways

APMAP integrates into the lipid metabolic pathway particularly those impacting triglyceride storage and hydrolysis. APMAP associates with proteins like perilipin which also participate in lipid droplet formation and breakdown. Additionally APMAP's involvement with AMP-activated protein kinase (AMPK) signaling influences cellular energy status linking it to pathways controlling metabolism and energy sensing.

APMAP shows association with metabolic syndrome and type 2 diabetes. Its role in lipid metabolism connects APMAP to insulin signaling pathways where altered expression or function may contribute to these metabolic disorders. APMAP's relationship with adiponectin a protein with anti-diabetic properties indicates its potential impact on glucose metabolism dysregulation. Understanding APMAP's function helps unravel molecular underpinnings of metabolic diseases offering insights for targeted therapeutic approaches.

style

left-column

style

left-column

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

타겟 정보

Exhibits strong arylesterase activity with beta-naphthyl acetate and phenyl acetate. May play a role in adipocyte differentiation.

See full target information APMAP

style

left-column

제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

eLife 12: PubMed37882444

2023

Asymmetric inheritance of centrosomes maintains stem cell properties in human neural progenitor cells.

Applications

Unspecified application

Species

Unspecified reactive species

Lars N Royall,Diana Machado,Sebastian Jessberger,Annina Denoth-Lippuner

제품이 사용된 논문 모두 보기

style

left-column

style

left-column

style

right-column

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-APMAP antibody

Immunocytochemistry/ Immunofluorescence - Anti-APMAP antibody (AB221453)

주요 정보

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

보완 제품

Primary Antibodies

Proteins & Peptides

Primary Antibodies

Primary Antibodies

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 기간

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

추가 정보

Biological function summary

Pathways

제품 프로토콜

타겟 정보

제품이 사용된 논문 (1)

Product promise