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AB199130

Anti-APOA1BP antibody

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(2 제품이 사용된 논문 )

Rabbit Polyclonal APOA1BP antibody. Suitable for IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human NAXE.

대체 명칭 보기

AIBP, APOA1BP, YJEFN1, NAXE, NAD(P)H-hydrate epimerase, Apolipoprotein A-I-binding protein, NAD(P)HX epimerase, YjeF N-terminal domain-containing protein 1, AI-BP, YjeF_N1

2 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-APOA1BP antibody (AB199130)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-APOA1BP antibody (AB199130)

Immunohistochemical analysis of paraffin embedded Human thyroid cancer tissue labeling APOA1BP with ab199130 at 1/15 dilution.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-APOA1BP antibody (AB199130)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-APOA1BP antibody (AB199130)

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue labeling APOA1BP with ab199130 at 1/15 dilution.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Synthetic Peptide within Human NAXE. The exact immunogen used to generate this antibody is proprietary information.

Q8NCW5

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대체품

Primary Antibodies

AB75114

Anti-APOA1BP antibody

Immunocytochemistry/ Immunofluorescence - Anti-APOA1BP antibody (AB75114)

  • 5
  • 1

보완 제품

Primary Antibodies

AB119857

Anti-CD86 antibody [GL-1]

  • 1
  • 2
Primary Antibodies

AB64693

Anti-CD206 antibody

BOND RX™ Validated

Western blot - Anti-CD206 antibody (AB64693)

  • 5
  • 42
Primary Antibodies

AB283655

Anti-iNOS antibody [RM1017]

BOND RX™ Validated|20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-iNOS antibody [RM1017] (AB283655)

  • 0
  • 1
Proteins & Peptides

AB276539

Recombinant Human APOA1BP protein (His tag)

SDS-PAGE - Recombinant Human APOA1BP protein (His tag) (AB276539)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/15 - 1/50", "IHCP-species-notes": "<p></p>" }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

APOA1BP also known as apolipoprotein A1 binding protein plays important roles in cellular lipid homeostasis and metabolism. This protein weighs approximately 28 kDa. APOA1BP is present in various tissues prominently in the mitochondria within liver and kidney cells. It displays binding affinity with apolipoprotein A1 which is an essential component of high-density lipoprotein (HDL).
Biological function summary

APOA1BP aids in stabilizing cellular processes that regulate lipid transport and cholesterol efflux. It works in close association with apolipoprotein A1 forming a functional complex that helps maintain lipid balance within cells. This interaction supports numerous cellular functions that are significant for normal metabolic activity.

Pathways

APOA1BP integrates into the reverse cholesterol transport pathway which is vital for recycling cholesterol from peripheral tissues back to the liver for excretion. It influences interactions with significant proteins such as HDL and other apolipoproteins contributing to cholesterol metabolism. Another related pathway involves lipid absorption where APOA1BP functions to facilitate efficient lipid distribution.

APOA1BP connects to cardiovascular disease due to its role in cholesterol metabolism and lipid transport. Disorders like atherosclerosis can occur when this protein's function in cholesterol efflux is impaired. Additionally APOA1BP links to inherited lipid disorders where its connection with apolipoprotein A1 and HDL becomes important in managing cholesterol levels and preventing disease progression.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity) (PubMed : 27616477). This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX (By similarity). Accelerates cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis (PubMed : 23719382).
See full target information NAXE
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제품이 사용된 논문 (2)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Journal for immunotherapy of cancer 11: PubMed37072348

2023

Intratumoral tertiary lymphoid structure (TLS) maturation is influenced by draining lymph nodes of lung cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Miao He,Qihua He,Xiuyu Cai,Jun Liu,Hongshen Deng,Feng Li,Ran Zhong,Yi Lu,Haoxin Peng,Xiangrong Wu,Zisheng Chen,Shen Lao,Caichen Li,Jianfu Li,Jianxing He,Wenhua Liang

EBioMedicine 74:103714 PubMed34818622

2021

Proteomic profiling identifies signatures associated with progression of precancerous gastric lesions and risk of early gastric cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Xue Li,Nai-Ren Zheng,Lin-Heng Wang,Zhong-Wu Li,Zong-Chao Liu,Hua Fan,Yi Wang,Jin Dai,Xiao-Tian Ni,Xin Wei,Ming-Wei Liu,Kai Li,Zhe-Xuan Li,Tong Zhou,Yang Zhang,Jing-Ying Zhang,Gaohaer Kadeerhan,Sha Huang,Wen-Hui Wu,Wei-Dong Liu,Xiu-Zhen Wu,Lan-Fu Zhang,Jian-Ming Xu,Markus Gerhard,Wei-Cheng You,Kai-Feng Pan,Wen-Qing Li,Jun Qin
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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