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AB239480

Anti-APOA4/Apo-AIV antibody [C8]

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(2 제품이 사용된 논문 )

Mouse Monoclonal APOA4/Apo-AIV antibody. Suitable for WB and reacts with Pig, Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Pig APOA4.

대체 명칭 보기

Apolipoprotein A-IV, Apo-AIV, ApoA-IV, Apolipoprotein A4, APOA4

2 이미지
Western blot - Anti-APOA4/Apo-AIV antibody [C8] (AB239480)
  • WB

Supplier Data

Western blot - Anti-APOA4/Apo-AIV antibody [C8] (AB239480)

All lanes:

Western blot - Anti-APOA4/Apo-AIV antibody [C8] (ab239480) at 3 µg/mL

All lanes:

Human serum

Predicted band size: 45 kDa

false

Western blot - Anti-APOA4/Apo-AIV antibody [C8] (AB239480)
  • WB

Supplier Data

Western blot - Anti-APOA4/Apo-AIV antibody [C8] (AB239480)

All lanes:

Western blot - Anti-APOA4/Apo-AIV antibody [C8] (ab239480) at 2 µg/mL

All lanes:

Recombinant pig APOA4/Apo-AIV protein

Predicted band size: 45 kDa

false

주요 정보

Host species

Mouse

Clonality

Monoclonal

Clone number

C8

Isotype

IgG1

Light chain 타입

kappa

Carrier free

No

Reacts with

Human, Pig

Applications

WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Pig APOA4.

O46409

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대체품

Primary Antibodies

AB231660

Anti-APOA4/Apo-AIV antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-APOA4/Apo-AIV antibody (AB231660)

  • 0
  • 0
Primary Antibodies

AB108200

Anti-APOA4/Apo-AIV antibody [EPR2895]

RabMAb|Recombinant

Immunoprecipitation - Anti-APOA4/Apo-AIV antibody [EPR2895] (AB108200)

  • 1
  • 1
Primary Antibodies

AB167350

Anti-APOA4/Apo-AIV antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-APOA4/Apo-AIV antibody (AB167350)

  • 0
  • 0

보완 제품

Assay Kits

AB214567

Human Apolipoprotein A-IV ELISA Kit

Recombinant|SimpleStep

ELISA - Human Apolipoprotein A-IV ELISA Kit (AB214567)

  • 4
  • 1
Primary Antibodies

AB32136

Anti-Amyloid Precursor Protein antibody [Y188]

BOND RX™ Validated|20ul selling size|RabMAb|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Amyloid Precursor Protein antibody [Y188] (AB32136)

  • 4
  • 9
Primary Antibodies

AB126597

Anti-PON1 antibody [EPR2893]

RabMAb|Recombinant

Immunoprecipitation - Anti-PON1 antibody [EPR2893] (AB126597)

  • 0
  • 1
Primary Antibodies

AB181547

Anti-Insulin antibody [EPR17359]

BOND RX™ Validated|RabMAb|Recombinant|Lab Essentials|20ul selling size|Advanced Validation

Multiplex immunohistochemistry - Anti-Insulin antibody [EPR17359] (AB181547)

  • 5
  • 11
Primary Antibodies

AB109750

Anti-Kir2.1/KCNJ2 antibody [EPR4530]

20ul selling size|RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-Kir2.1/KCNJ2 antibody [EPR4530] (AB109750)

  • 1
  • 1
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.2-3 µg/mL", "WB-species-notes": "<p></p>" }, "Pig": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.2-3 µg/mL", "WB-species-notes": "<p></p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
Purification 관련 사항
Purified from TCS by antigen-specific affinity chromatography followed by Protein A affinity chromatography.
보관 버퍼
pH: 7.4 Preservative: 0.011% Proclin 300 Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

APOA4 also known as Apo-AIV or apolipoprotein A4 is a protein mainly expressed in the small intestine and liver. It has a molecular mass of approximately 46 kDa. This protein plays a significant role in lipid metabolism by facilitating the transport of lipids in the bloodstream. APOA4 exists in the plasma and associates predominately with high-density lipoproteins (HDL) and to a lesser extent with chylomicrons.
Biological function summary

Apolipoprotein A4 acts as an important player in the regulation of lipid homeostasis and satiety. This protein is not part of a complex but enhances the efficiency of lipid absorption and transport. APOA4 reacts with enzymes like lecithin-cholesterol acyltransferase which is essential in the maturation of HDL particles. This interaction supports cholesterol efflux and assists in maintaining cholesterol balance within the body.

Pathways

APOA4 is heavily involved in the reverse cholesterol transport pathway which is important for removing excess cholesterol from cells and tissues taking it back to the liver for excretion. Within this pathway APOA4 interacts with key proteins like apolipoprotein A1 and lecithin-cholesterol acyltransferase to aid in this lipid transport mechanism. It also participates in a related lipid homeostasis pathway enhancing lipid absorption efficiency.

Research links APOA4 to atherosclerosis and obesity. Altered expression or function of apolipoprotein A4 often correlates with increased cardiovascular disease risk due to its role in cholesterol transport. It is associated with apolipoprotein A1 as both of these proteins significantly impact lipid profiles related to cardiovascular health. The ability of APOA4 to influence satiety also connects it to obesity suggesting a role in energy balance regulation.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.
See full target information APOA4
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제품이 사용된 논문 (2)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Respiratory research 24:83 PubMed36927357

2023

Proteome of airway surface liquid and mucus in newborn wildtype and cystic fibrosis piglets.

Applications

Unspecified application

Species

Unspecified reactive species

Ana M Rodriguez-Piñeiro,Florian Jaudas,Nikolai Klymiuk,Andrea Bähr,Gunnar C Hansson,Anna Ermund

Animals : an open access journal from MDPI 11: PubMed33375218

2020

Fat Encapsulation Reduces Diarrhea in Piglets Partially by Repairing the Intestinal Barrier and Improving Fatty Acid Transport.

Applications

Unspecified application

Species

Unspecified reactive species

Min Tian,Jiaming Chen,Zhihui Wu,Hanqing Song,Fei Yang,Chang Cui,Fang Chen,Shihai Zhang,Wutai Guan
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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