JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB317423

Anti-BarX1 antibody [S01-3A3]

Be the first to review this product! 리뷰 제출

|

(0 출판물)

Rabbit Recombinant Monoclonal BARX1 antibody. Suitable for WB and reacts with Human, Rat, Chinese hamster samples.

대체 명칭 보기

Homeobox protein BarH-like 1, BARX1

1 이미지
Western blot - Anti-BarX1 Antibody [S01-3A3] (AB317423)
  • WB

Supplier Data

Western blot - Anti-BarX1 Antibody [S01-3A3] (AB317423)

All lanes:

Western blot - Anti-BarX1 Antibody [S01-3A3] (ab317423) at 1/1000 dilution

Lane 1:

HeLa cell lysate

Lane 2:

CHO-K1 cell lysate

Lane 3:

C6 cell lysate

Lane 4:

Ramos cell lysate

Predicted band size: 28 kDa

false

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

S01-3A3

Isotype

IgG

Carrier free

No

Reacts with

Human, Rat, Chinese hamster

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

style
left-column

보완 제품

Primary Antibodies

AB235096

Anti-BARHL1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BARHL1 antibody (AB235096)

  • 0
  • 0
Primary Antibodies

AB20128

Anti-BarX2 antibody [BAR X2 8A7/1]

  • 4
  • 1
Primary Antibodies

AB183734

Anti-GFP antibody [EPR14104]

RabMAb|Recombinant|Lab Essentials|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GFP antibody [EPR14104] (AB183734)

  • 5
  • 24
Primary Antibodies

AB47639

Anti-Perilipin 3/TIP47 antibody

Western blot - Anti-Perilipin 3/TIP47 antibody (AB47639)

  • 0
  • 0
style
left-column

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>" }, "Chinese hamster": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000", "WB-species-notes": "<p></p>" } } }
style
left-column

제품 세부 정보

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

style
left-column

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification
보관 버퍼
pH: 7.4 Preservative: 0.01% Sodium azide Constituents: 55.08% Water, 40% Glycerol (glycerin, glycerine), 0.98% Tris glycine, 0.88% Sodium chloride, 0.05% BSA
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
style
left-column

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

BarX1 also known as BarH-like homeobox 1 is a transcription factor with a molecular mass of approximately 29 kDa. It is part of the Bar family of proteins which play essential roles in development. BarX1's primary expression occurs in the central nervous system and mesenchymal tissues during embryonic development. In adults BarX1 shows limited expression in specific tissues such as the stomach where it may serve various regulatory functions.
Biological function summary

BarX1 functions in the development of multiple organ systems particularly in teeth and stomach. It acts by influencing the differentiation and proliferation of cells during the formation of these structures. BarX1 is known to be part of a regulatory complex that controls the expression of genes critical for morphogenesis and tissue specification. Its interaction with other homeobox proteins further expands its impact on development.

Pathways

BarX1 interacts in key developmental signaling pathways such as Wnt and Hedgehog. These pathways play significant roles in development influencing cell fate and patterning. BarX1's interaction with proteins like beta-Catenin in the Wnt pathway helps modulate the activity of downstream genes necessary for development. By participating in these pathways BarX1 helps maintain the balance between cell proliferation and differentiation.

Dysregulation of BarX1 expression has been linked to conditions such as gastric cancer and tooth agenesis. In gastric cancer abnormal BarX1 levels can disrupt normal gene expression leading to uncontrolled cell growth and tumor development. Connections also exist between BarX1 and E-cadherin; alterations in this interaction can influence cancer progression. In tooth agenesis insufficient BarX1 activity can impair the formation of dental tissues resulting in missing teeth. Understanding these associations aids in developing targeted therapeutic interventions.
style
left-column
style
left-column

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

타겟 정보

Transcription factor, which is involved in craniofacial development, in odontogenesis and in stomach organogenesis. May have a role in the differentiation of molars from incisors. Plays a role in suppressing endodermal Wnt activity (By similarity). Binds to a regulatory module of the NCAM promoter.
See full target information Homeobox protein BarH-like 1

Additional targets

,
style
left-column
style
left-column
style
right-column

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com