Rabbit Polyclonal beta Sarcoglycan antibody. Suitable for IHC-P, WB and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human SGCB.
대체 명칭 보기
Beta-sarcoglycan, Beta-SG, 43 kDa dystrophin-associated glycoprotein, A3b, 43DAG, SGCB
- IHC-P
Unknown
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-beta Sarcoglycan antibody (AB135954)
Immunohistochemical analysis of paraffin-embedded Human brain tissue labelling beta Sarcoglycan with ab135954 at 1/50 dilution.
- WB
Unknown
Western blot - Anti-beta Sarcoglycan antibody (AB135954)
All lanes:
Western blot - Anti-beta Sarcoglycan antibody (ab135954) at 1/500 dilution
All lanes:
A549 cell extract at 30 µg
Predicted band size: 35 kDa
false
Reactivity 정보
특성 및 보관 정보
제형
Purification 테크닉
보관 버퍼
배송 시 보관 조건
적절한 단기 보관 조건
적절한 장기 보관 조건
추가 정보
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
Beta Sarcoglycan acts to maintain the stability of the muscle cell's sarcolemma. It forms part of the sarcoglycan complex which is one component of a larger dystrophin-glycoprotein complex. This complex protects muscle fibers from the stress of contraction. By ensuring the integrity of the muscle membrane Beta Sarcoglycan contributes to muscle fiber repair and regeneration reducing the risk of damage from repetitive use.
Pathways
Beta Sarcoglycan belongs to the dystrophin-associated glycoprotein complex playing a role in the linkage between the cytoskeleton and extracellular matrix. This involvement occurs primarily in the DGC signaling pathway. The interaction with dystrophin and other sarcoglycans ensures effective signal transduction and mechanical stability during muscle contraction. It relates to proteins including dystrophin itself and other sarcoglycans like alpha and gamma that cooperate in the same pathway.
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타겟 정보
제품이 사용된 논문 (2)
Recent publications for all applications. Explore the 전체 목록 and refine your search
Experimental and therapeutic medicine 27:97 PubMed38356676
2024
Applications
Unspecified application
Species
Unspecified reactive species
Cellular physiology and biochemistry : internation 49:2099-2110 PubMed30257238
2018
Applications
Unspecified application
Species
Unspecified reactive species
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