AB204791

Anti-BHLHB5 antibody

Name: Anti-BHLHB5 antibody
Brand: Abcam Limited
SKU: AB204791
Rating: 5 (2 reviews)

(2 리뷰들)

(4 제품이 사용된 논문 )

Rabbit Polyclonal BHLHB5 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Recombinant Fragment Protein within Human BHLHE22 aa 1-100.

대체 명칭 보기

BHLHB5, TNRC20, BHLHE22, Class E basic helix-loop-helix protein 22, bHLHe22, Class B basic helix-loop-helix protein 5, Trinucleotide repeat-containing gene 20 protein, bHLHb5

1 이미지

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BHLHB5 antibody (AB204791)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BHLHB5 antibody (AB204791)

Immunohistochemical analysis of paraffin embedded Human cerebellum tissue labeling BHLHB5 with ab204791 at 1/2500 dilution.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human BHLHE22 aa 1-100. The exact immunogen used to generate this antibody is proprietary information.

Q8NFJ8

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/2500 - 1/5000", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol." }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Hamster": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Immunogen

보관 버퍼

pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)

배송 시 보관 조건

Blue Ice

적절한 단기 보관 기간

1-2 weeks

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Inhibits DNA binding of TCF3/E47 homodimers and TCF3 (E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. Despite the presence of an intact basic domain, does not bind to DNA (By similarity). In the brain, may function as an area-specific transcription factor that regulates the postmitotic acquisition of area identities and elucidate the genetic hierarchy between progenitors and postmitotic neurons driving neocortical arealization. May be required for the survival of a specific population of inhibitory neurons in the superficial laminae of the spinal cord dorsal horn that may regulate pruritis. Seems to play a crucial role in the retinogenesis, in the specification of amacrine and bipolar subtypes. Forms with PRDM8 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation.

See full target information BHLHE22

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제품이 사용된 논문 (4)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Nature 638:469-478 PubMed39814878

2025

Specification of claustro-amygdalar and palaeocortical neurons and circuits.

Applications

Unspecified application

Species

Unspecified reactive species

Navjot Kaur,Rothem Kovner,Forrest O Gulden,Mihovil Pletikos,David Andrijevic,Tianjia Zhu,John Silbereis,Mikihito Shibata,Akemi Shibata,Yuting Liu,Shaojie Ma,Nikkita Salla,Xabier de Martin,Thomas S Klarić,Megan Burke,Daniel Franjic,Hyesun Cho,Matthew Yuen,Ipsita Chatterjee,Paula Soric,Devippriya Esakkimuthu,Markus Moser,Gabriel Santpere,Yann S Mineur,Kartik Pattabiraman,Marina R Picciotto,Hao Huang,Nenad Sestan

Neuroscience 455:65-78 PubMed33346116

2020

Atypical Neocortical Development in the Cited2 Conditional Knockout Leads to Behavioral Deficits Associated with Neurodevelopmental Disorders.

Applications

Unspecified application

Species

Unspecified reactive species

Nikolaus R Wagner,Jessica L MacDonald

Nature communications 11:4287 PubMed32855419

2020

Warsaw Breakage Syndrome associated DDX11 helicase resolves G-quadruplex structures to support sister chromatid cohesion.

Applications

Unspecified application

Species

Unspecified reactive species

Janne J M van Schie,Atiq Faramarz,Jesper A Balk,Grant S Stewart,Erika Cantelli,Anneke B Oostra,Martin A Rooimans,Joanna L Parish,Cynthia de Almeida Estéves,Katja Dumic,Ingeborg Barisic,Karin E M Diderich,Marjon A van Slegtenhorst,Mohammad Mahtab,Francesca M Pisani,Hein Te Riele,Najim Ameziane,Rob M F Wolthuis,Job de Lange

Frontiers in cell and developmental biology 7:351 PubMed31921861

2019

Role of TGF-β/Smad Pathway in the Transcription of Pancreas-Specific Genes During Beta Cell Differentiation.

Applications

Unspecified application

Species

Unspecified reactive species

Yuhua Gao,Ranxi Zhang,Shanshan Dai,Xue Zhang,Xiangchen Li,Chunyu Bai

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-BHLHB5 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BHLHB5 antibody (AB204791)

주요 정보

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

보완 제품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 기간

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

제품 프로토콜

타겟 정보

제품이 사용된 논문 (4)

Product promise