AB224180

Biotin Anti-IGLC1 antibody [RM127]

Recombinant
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Rabbit Recombinant Monoclonal IGLC1 antibody - conjugated to Biotin. Suitable for IHC, ELISA and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Native Full Length Protein corresponding to Human Immunoglobulin lambda constant 1.

대체 명칭 보기

Immunoglobulin lambda constant 1, Ig lambda chain C region MGC, Ig lambda-1 chain C region, IGLC1

3 이미지

Supplier Data

Immunohistochemistry - Biotin Anti-IGLC1 antibody [RM127] (AB224180)

Human tonsil tissue stained for IGLC1 using ab224180 at 2 μg/ml in immunohistochemical analysis.

ELISA - Biotin Anti-IGLC1 antibody [RM127] (AB224180)

ELISA

Supplier Data

ELISA - Biotin Anti-IGLC1 antibody [RM127] (AB224180)

ELISA of human immunoglobulins shows ab224180 reacts to the lambda light chain of human immunoglobulins. No cross reactivity with the kappa light chain, mouse IgG, rat IgG, or goat IgG. The plate was coated with 50 ng/well of different immunoglobulins. 200 ng/mL or 50 ng/mL of ab224180 was used as the primary antibody. An alkaline phosphatase conjugated Anti-Rabbit IgG was used as the secondary antibody.

ELISA

Supplier Data

ELISA - Biotin Anti-IGLC1 antibody [RM127] (AB224180)

A titer ELISA using ab224180. The plate was coated with different amounts of human IgG3λ. A serial dilution of ab224180 was used as the primary antibody. An alkaline phosphatase conjugated Anti-Rabbit IgG was used as the secondary antibody.

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

RM127

Isotype

IgG

Conjugation

Biotin

Excitation/Emission

Carrier free

Reacts with

Human

Applications

IHC, ELISA

applications

Immunogen

Native Full Length Protein corresponding to Human Immunoglobulin lambda constant 1.

P0CG04

Specificity

ab224180 reacts to the lambda light chain of human immunoglobulins.

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHC" : {"fullname" : "Immunohistochemistry", "shortname":"IHC"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHC-species-checked": "testedAndGuaranteed", "IHC-species-dilution-info": "0.5-2 µg/mL", "IHC-species-notes": "", "ELISA-species-checked": "testedAndGuaranteed", "ELISA-species-dilution-info": "0.05-0.2 µg/mL", "ELISA-species-notes": "" }, "Mouse": { "IHC-species-checked": "notRecommended", "IHC-species-dilution-info": "0.5-2 g/mL", "IHC-species-notes": "", "ELISA-species-checked": "notRecommended", "ELISA-species-dilution-info": "0.05-0.2 µg/mL", "ELISA-species-notes": "" }, "Rat": { "IHC-species-checked": "notRecommended", "IHC-species-dilution-info": "0.5-2 g/mL", "IHC-species-notes": "", "ELISA-species-checked": "notRecommended", "ELISA-species-dilution-info": "0.05-0.2 µg/mL", "ELISA-species-notes": "" }, "Goat": { "IHC-species-checked": "notRecommended", "IHC-species-dilution-info": "0.5-2 g/mL", "IHC-species-notes": "", "ELISA-species-checked": "notRecommended", "ELISA-species-dilution-info": "0.05-0.2 µg/mL", "ELISA-species-notes": "" } } }

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Protein A

Purification 관련 사항

ab224180 was purified from an animal origin–free culture supernatant.

보관 버퍼

Preservative: 0.09% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 1% BSA

배송 시 보관 조건

Blue Ice

적절한 단기 보관 기간

1-2 weeks

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Stable for 12 months at -20°C|Store in the dark

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed : 20176268, PubMed : 22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed : 17576170, PubMed : 20176268).

See full target information Immunoglobulin lambda constant 1

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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Oxidative medicine and cellular longevity 2019:1970818 PubMed31093311

2019

CIAPIN1 Targeted NHE1 and ERK1/2 to Suppress NSCLC Cells' Metastasis and Predicted Good Prognosis in NSCLC Patients Receiving Pulmonectomy.

Applications

Unspecified application

Species

Unspecified reactive species

Jian Wang,Ying Zhou,Li Ma,Shannan Cao,Wei Gao,Qingqing Xiong,Kaiyuan Wang,Lili Yang

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Biotin Anti-IGLC1 antibody [RM127]

Immunohistochemistry - Biotin Anti-IGLC1 antibody [RM127] (AB224180)

ELISA - Biotin Anti-IGLC1 antibody [RM127] (AB224180)

ELISA - Biotin Anti-IGLC1 antibody [RM127] (AB224180)

주요 정보

Host species

Clonality

Clone number

Isotype

Conjugation

Excitation/Emission

Carrier free

Reacts with

Applications

Immunogen

Specificity

보완 제품

Assay Kits

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

Purification 관련 사항

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 기간

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

제품 프로토콜

타겟 정보

제품이 사용된 논문 (1)

Product promise