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AB20027

Biotin Anti-Mycobacterium tuberculosis antibody

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(1 출판물)

Anti-Mycobacterium tuberculosis antibody conjugated to Biotin is a rabbit polyclonal antibody suitable for IHC-P.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Conjugation

Biotin

Excitation/Emission
Carrier free

No

Reacts with

Mycobacterium tuberculosis

Applications

IHC-P

applications

Specificity

Minimum of two major M. tuberculosis bands by immunoelectrophoresis (gamma & beta).

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대체품

Primary Antibodies

AB905

Anti-Mycobacterium tuberculosis antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mycobacterium tuberculosis antibody (AB905)

  • 4
  • 2
Primary Antibodies

AB21189

HRP Anti-Mycobacterium tuberculosis antibody

  • 0
  • 0
Primary Antibodies

AB20962

FITC Anti-Mycobacterium tuberculosis antibody

  • 2
  • 1
Primary Antibodies

AB214721

Anti-Mycobacterium tuberculosis antibody

  • 0
  • 0

보완 제품

Primary Antibodies

AB905

Anti-Mycobacterium tuberculosis antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mycobacterium tuberculosis antibody (AB905)

  • 4
  • 2
Primary Antibodies

AB312328

Anti-Mycobacterium tuberculosis Ag85B antibody [EPR28401-54]

BOND RX™ Validated|20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mycobacterium tuberculosis Ag85B antibody [EPR28401-54] (AB312328)

  • 0
  • 0
Primary Antibodies

AB53280

Anti-Cytokeratin 8 antibody [EP1628Y] - Cytoskeleton Marker

KO Validated|RabMAb|Recombinant|Lab Essentials|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 8 antibody [EP1628Y] - Cytoskeleton Marker (AB53280)

  • 5
  • 9
Primary Antibodies

AB20962

FITC Anti-Mycobacterium tuberculosis antibody

  • 2
  • 1
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mycobacterium tuberculosis": { "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
Purification 관련 사항
IgG fraction covalently coupled with the N-Hydroxysuccinimide ester of biotin under mild conditions to give a high degree of substitution.
보관 버퍼
Preservative: 0.1% Sodium azide Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Mycobacterium tuberculosis sometimes referred to as M. tuberculosis is a pathogenic bacterial species in the Mycobacterium genus. It is the causative agent of tuberculosis (TB) in humans and has a relatively large cellular mass characterized by a thick and complex cell wall rich in mycolic acids. This bacterium expresses in the lungs where it primarily resides in pulmonary macrophages after inhalation. The robust cell wall serves as a barrier against phagocytosis and contributes to its resistance to many antimicrobial agents.
Biological function summary

The bacteria stimulate a host immune response causing the formation of granulomas which are small nodular aggregations of immune cells. Mycobacterium tuberculosis employs several mechanisms to inhibit the lysosomal degradation processes in macrophages. It is part of a complex interplay involving the immune system which tries to control its spread. This interaction allows it to persist in a dormant state within the host making it difficult to eradicate completely and able to reactivate later.

Pathways

Mycobacterium tuberculosis's survival and pathogenicity involve several critical biological processes. The bacteria actively dodge destruction through pathways that inhibit host cell apoptosis and modulate cytokine production. Specific proteins like the 6-kda early secretory antigen target (ESAT-6) and culture filtrate protein 10 (CFP-10) complexes play a vital role in these mechanisms manipulating host immune signaling pathways to facilitate prolonged infection.

Mycobacterium tuberculosis is directly associated with tuberculosis a disease that can affect different body organs but most often targets the lungs. The pathogen’s persistence mechanisms implicate it in chronic infections and proteins like Ag85 complex interact with host defenses to further complicate control of the disease. Another disorder linked to its infection is latent TB where the bacteria remain inactive but viable within the host posing ongoing public health challenges.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

See full target information Mycobacterium tuberculosis

대체 명칭 보기

M. tuberculosis
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Veterinary pathology 50:343-6 PubMed22711744

2012

Probable Blastomyces dermatitidis infection in a young rat.

Applications

Unspecified application

Species

Unspecified reactive species

S C Chang,S L Hsuan,C C Lin,W C Lee,M S Chien,L C Chen,J H Wu,S J Cheng,C L Chen,J W Liao
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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