AB233505

Biotin Anti-VEGFB antibody

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Anti-VEGFB antibody conjugated to Biotin is a rabbit polyclonal antibody suitable for Western blot, sELISA.

3 이미지

Sandwich ELISA - Biotin Anti-VEGFB antibody (AB233505)

sELISA

Supplier Data

Sandwich ELISA - Biotin Anti-VEGFB antibody (AB233505)

ab233505, in conjunction with Anti-human VEGFB as a capture antibody, allows the detection of at least 2000-4000 pg/ml of Recombinant human VEGFB.

Supplier Data

Western blot - Biotin Anti-VEGFB antibody (AB233505)

Non-reduced.

All lanes:

Western blot - Biotin Anti-VEGFB antibody (ab233505) at 0.2 µg/mL

Lane 1:

Recombinant human VEGFB protein, 250 ng

Lane 2:

Recombinant human VEGFB protein, 125 ng

Lane 3:

Recombinant human VEGFB protein, 62.5 ng

Lane 4:

Recombinant human VEGFB protein, 31.25 ng

Lane 5:

Recombinant human VEGFB protein, 15.625 ng

Lane 6:

Recombinant human VEGFB protein, 7.8 ng

Lane 7:

Recombinant human VEGFB protein, 3.9 ng

Lane 8:

Recombinant human VEGFB protein, 1.95 ng

Lane 9:

Recombinant human VEGFB protein, 0.98 ng

Lane 10:

Recombinant human VEGFB protein, 0.49 ng

Lane 11:

Recombinant human VEGFB protein, 0.24 ng

Predicted band size: 22 kDa

false

Supplier Data

Western blot - Biotin Anti-VEGFB antibody (AB233505)

Reduced.

Lanes 1 - 10:

Western blot - Biotin Anti-VEGFB antibody (ab233505) at 0.2 µg/mL

Lane 11:

Western blot - Biotin Anti-VEGFB antibody (ab233505) at 0.2 µg

Lane 1:

Recombinant human VEGFB protein, 250 ng

Lane 2:

Recombinant human VEGFB protein, 125 ng

Lane 3:

Recombinant human VEGFB protein, 62.5 ng

Lane 4:

Recombinant human VEGFB protein, 31.25 ng

Lane 5:

Recombinant human VEGFB protein, 15.625 ng

Lane 6:

Recombinant human VEGFB protein, 7.8 ng

Lane 7:

Recombinant human VEGFB protein, 3.9 ng

Lane 8:

Recombinant human VEGFB protein, 1.95 ng

Lane 9:

Recombinant human VEGFB protein, 0.98 ng

Lane 10:

Recombinant human VEGFB protein, 0.49 ng

Lane 11:

Recombinant human VEGFB protein, 0.24 ng

Predicted band size: 22 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Conjugation

Biotin

Excitation/Emission

Carrier free

Yes

Reacts with

Human

Applications

sELISA, WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human VEGFB.

P49765

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "sELISA-species-checked": "predicted", "sELISA-species-dilution-info": "", "sELISA-species-notes": "" }, "Recombinant full length protein - Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.1-0.2 µg/mL", "WB-species-notes": "<p></p>", "sELISA-species-checked": "testedAndGuaranteed", "sELISA-species-dilution-info": "0.25-1 µg/mL", "sELISA-species-notes": "<p></p>" } } }

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특성 및 보관 정보

제형

Lyophilized

Purification 테크닉

Affinity purification Immunogen

Purification 관련 사항

ab233505 purified by affinity chromatography and then biotinylated.

보관 버퍼

Constituents: PBS

배송 시 보관 조건

Blue Ice

적절한 단기 보관 기간

1-2 weeks

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle|Store in the dark

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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

VEGFB also known as vascular endothelial growth factor B is a member of the VEGF family. It has a molecular mass of approximately 34-35 kDa. VEGFB interacts with its receptors to promote angiogenesis increasing blood supply to tissues. Expression of VEGFB occurs in the heart skeletal muscle and various endothelial cells. It also shows expression in tissues undergoing high metabolic activities. Besides its angiogenic role VEGFB exhibits participation in metabolic regulation.

Biological function summary

VEGFB supports angiogenesis by promoting endothelial cell growth and migration. It acts as a signal protein not forming part of a larger complex. VEGFB binds to VEGFR-1 (Flt-1) receptor which is involved in transmitting the growth-promoting signals. Its function extends to the regulation of fatty acid uptake into tissues highlighting its role in lipid metabolism and energy utilization.

Pathways

The signalling activities of VEGFB are significant in angiogenesis and metabolic pathways. VEGFB interacts closely with the VEGF-A pathway which is vital for forming new blood vessels. It also shares interactive roles with similar proteins such as VEGF-C and VEGF-D contributing to various angiogenic processes and cellular growth signalling systems.

Understanding VEGFB's role is important in conditions like cardiovascular disease and metabolic syndrome. Altered VEGFB signalling may link to heart diseases due to its regulatory function in maintaining heart vasculature. VEGFB has connections with VEGFR-1 and VEGF-A indicating its potential involvement in endothelial dysfunction and highlighting its significance in therapeutic strategies targeting such diseases.

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Growth factor for endothelial cells. VEGF-B167 binds heparin and neuropilin-1 whereas the binding to neuropilin-1 of VEGF-B186 is regulated by proteolysis.

See full target information VEGFB

대체 명칭 보기

VRF, VEGFB, Vascular endothelial growth factor B, VEGF-B, VEGF-related factor

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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

BMC cancer 25:1417 PubMed40898094

2025

KRAS mutation promotes immune escape of lung adenocarcinoma via ZNF24/SLC7A5/PD-L1 axis.

Applications

Unspecified application

Species

Unspecified reactive species

Leilei Li,Qiang Feng,Ya Jiang,Lilin Yang,Hong Fang,Wenmang Xu,Yuanyuan Wang,Xinyan Pan,Julun Yang

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Biotin Anti-VEGFB antibody

Sandwich ELISA - Biotin Anti-VEGFB antibody (AB233505)

Western blot - Biotin Anti-VEGFB antibody (AB233505)

Western blot - Biotin Anti-VEGFB antibody (AB233505)

주요 정보

Host species

Clonality

Isotype

Conjugation

Excitation/Emission

Carrier free

Reacts with

Applications

Immunogen

대체품

Primary Antibodies

Primary Antibodies

보완 제품

Assay Kits

Assay Kits

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

Purification 관련 사항

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 기간

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

추가 정보

Biological function summary

Pathways

제품 프로토콜

타겟 정보

대체 명칭 보기

제품이 사용된 논문 (1)

Product promise