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AB59406

Anti-BRAF (phospho T599) antibody

5

(1 리뷰)

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(1 출판물)

Rabbit Polyclonal BRAF phospho T599 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human BRAF pT599 aa 550-650.
1 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BRAF (phospho T599) antibody (AB59406)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-BRAF (phospho T599) antibody (AB59406)

Immunohistochemical analysis of paraffin embedded human breast carcinoma tissue using ab59406 at 1/50 dilution, in the presence (right) and absence (left) of immunising phosphopeptide.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Synthetic Peptide within Human BRAF pT599 aa 550-650. The exact immunogen used to generate this antibody is proprietary information.

P15056

Specificity

This antibody detects endogenous levels of B Raf only when phosphorylated at threonine 598.

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>" } } }

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
Purification 관련 사항
The antibody against non-phosphopeptide was removed by chromatographyusing non-phosphopeptide corresponding to the phosphorylation site.
보관 버퍼
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
보관 정보
Stable for 12 months at -20°C

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

타겟 정보

Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus (Probable). Phosphorylates MAP2K1, and thereby activates the MAP kinase signal transduction pathway (PubMed : 21441910, PubMed : 29433126). Phosphorylates PFKFB2 (PubMed : 36402789). May play a role in the postsynaptic responses of hippocampal neurons (PubMed : 1508179).
See full target information BRAF pT599

대체 명칭 보기

BRAF1, RAFB1, BRAF, Serine/threonine-protein kinase B-raf, Proto-oncogene B-Raf, p94, v-Raf murine sarcoma viral oncogene homolog B1

제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

The Journal of neuroscience : the official journal of the Society for Neuroscience 32:11864-78 PubMed22915127

2012

Social, communication, and cortical structural impairments in Epac2-deficient mice.

Applications

Unspecified application

Species

Mouse

Deepak P Srivastava,Kelly A Jones,Kevin M Woolfrey,Jeffrey Burgdorf,Theron A Russell,Abigail Kalmbach,Hyerin Lee,Connie Yang,Mazdak M Bradberry,David Wokosin,Joseph R Moskal,Manuel F Casanova,Jack Waters,Peter Penzes
제품이 사용된 논문 모두 보기

Product promise

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