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AB68546

Anti-BTN3A2 antibody

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Mouse Polyclonal BTN3A2 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human BTN3A2.
1 이미지
Western blot - Anti-BTN3A2 antibody (AB68546)
  • WB

Unknown

Western blot - Anti-BTN3A2 antibody (AB68546)

All lanes:

Western blot - Anti-BTN3A2 antibody (ab68546) at 1/500 dilution

All lanes:

human spleen lysate at 50 µg

Secondary

All lanes:

Goat Anti-Mouse IgG (H&L) at 1/2500 dilution

Predicted band size: 36 kDa

Observed band size: 36 kDa

false

주요 정보

Host species

Mouse

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human BTN3A2.

P78410

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보완 제품

Assay Kits

AB323689

Human BTN3A2 + BTN3A3 ELISA Kit- Extracellular

Recombinant|SimpleStep

Sandwich ELISA - Human BTN3A2 + BTN3A3 ELISA Kit- Extracellular (AB323689)

  • 0
  • 0
Assay Kits

AB300307

Human Factor IX/PTC ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Human Factor IX/PTC ELISA Kit (AB300307)

  • 5
  • 1
Primary Antibodies

AB319166

Anti-TBR2 / Eomes antibody [RM2055]

BOND RX™ Validated|20ul selling size|Recombinant|RabMAb

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TBR2 / Eomes antibody [RM2055] (AB319166)

  • 0
  • 0
Primary Antibodies

AB16667

Anti-Ki67 antibody [SP6]

BOND RX™ Validated|KO Validated|RabMAb|Advanced Validation|Recombinant|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Ki67 antibody [SP6] (AB16667)

  • 5
  • 133
Primary Antibodies

AB10799

Anti-Histone H3 antibody [mAbcam 10799] - Nuclear Marker and ChIP Grade

BOND RX™ Validated

Western blot - Anti-Histone H3 antibody [mAbcam 10799] - Nuclear Marker and ChIP Grade (AB10799)

  • 4
  • 17
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
pH: 7.4 Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

BTN3A2 also known as Butyrophilin Subfamily 3 Member A2 is a protein involved in the immune response. It has a molecular weight of approximately 35 kDa. BTN3A2 expresses in a variety of tissues especially in immune-related cells like T-cells. It forms part of the butyrophilin family known for modulating immune cell functions. The protein is anchored in the cell membrane indicating its role in cell signaling.
Biological function summary

BTN3A2 participates in immune regulation and modulation of T-cell activity. It functions as part of the BTN3A family complex working alongside BTN3A1 and BTN3A3. This protein family influences T-cell receptor signaling and activation contributing to the immune system's ability to respond to pathogens and infections. BTN3A2 plays a role in linking extracellular and intracellular signals that affect immune cell behavior.

Pathways

BTN3A2 integrates within the adaptive immune signaling pathways. One key pathway is the T-cell receptor signaling pathway where BTN3A2 collaborates with BTN3A1 to modulate immune responses. Another significant involvement is in the gamma delta T-cell activation pathway. BTN3A2 partners with proteins like phosphoantigens and other butyrophilins emphasizing its role in controlling T-cell mediated immune functions.

BTN3A2 relates to certain autoimmune conditions and cancers. Altered expression of BTN3A2 connects to disorders like psoriasis where dysregulated immune activity plays a part. The protein also connects to chronic lymphocytic leukemia as abnormal BTN3A2 signaling could drive leukemic T-cell behavior. Through these diseases BTN3A2 associates with related proteins such as BTN3A1 and histone deacetylases interacting in pathways disrupted in these conditions.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Plays a role in T-cell responses in the adaptive immune response. Inhibits the release of IFNG from activated T-cells.
See full target information BTN3A2

대체 명칭 보기

BT3.2, BTF3, BTF4, BTN3A2, Butyrophilin subfamily 3 member A2
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Nature communications 13:4268 PubMed35879332

2022

Integrin α3β1 promotes vessel formation of glioblastoma-associated endothelial cells through calcium-mediated macropinocytosis and lysosomal exocytosis.

Applications

Unspecified application

Species

Unspecified reactive species

Eunnyung Bae,Ping Huang,Gaёlle Müller-Greven,Dolores Hambardzumyan,Andrew Edward Sloan,Amy S Nowacki,Nicholas Marko,Cathleen R Carlin,Candece L Gladson
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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