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AB236288

Anti-C19orf47 antibody

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Rabbit Polyclonal C19orf47 antibody. Suitable for WB, IHC-P and reacts with Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human C19orf47 aa 1-300.

대체 명칭 보기

Uncharacterized protein C19orf47, C19orf47

2 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C19orf47 antibody (AB236288)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C19orf47 antibody (AB236288)

Paraffin-embedded human testis tissue stained for C19orf47 using ab236288 at 1/100 dilution in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C19orf47 antibody (AB236288)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C19orf47 antibody (AB236288)

Paraffin-embedded human small intestine tissue stained for C19orf47 using ab236288 at 1/100 dilution in immunohistochemical analysis.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human C19orf47 aa 1-300. The exact immunogen used to generate this antibody is proprietary information.

Q8N9M1

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
Purification 관련 사항
Purity >95%.
보관 버퍼
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

C19orf47 also known by alternate names such as Chromosome 19 Open Reading Frame 47 is a protein-coding gene located on human chromosome 19. It encodes a protein with a mass of approximately 46 kDa. This protein has localization in the cytoplasm and nucleus showing expression across various tissues but particularly enriched in immune cells. Researchers have suggested roles in cellular processes due to its conserved domains but the exact mechanical functions of C19orf47 remain not fully described.
Biological function summary

C19orf47 plays a role in the regulation of immune response possibly impacting cell signaling and proliferation. It functions as part of a larger protein complex interacting with key cellular machinery to modulate various biological processes. The protein has close associations with other regulatory proteins that influence immune cell dynamics. This suggests that C19orf47 may have broader implications in immune system homeostasis and adaptability.

Pathways

The evolutionarily conserved protein C19orf47 is involved in pathways linked to immune signaling networks. It participates in the regulation of signal transduction pathways such as the NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) pathway critical for immune and inflammatory responses. Additionally C19orf47 interacts with proteins like IκB influencing the pathway's activation and inhibition processes. This indicates its potential role in modulating immune responses and cellular defense mechanisms.

Research implicates C19orf47 in conditions related to immune dysregulation such as autoimmune diseases and certain cancers. It has connections to proteins involved in autoimmune diseases highlighting a potential role in disease pathogenesis due to alterations in immune signaling. Investigations continue to explore its association with other proteins like TNF (tumor necrosis factor) in these disorders. Understanding the involvement of C19orf47 in disease can lead to new insights into disease mechanisms and therapeutic targets.

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Communications biology 8:514 PubMed40155473

2025

Defining gastric cancer ecology: the crucial roles of TREM2 macrophages and fibroblasts in tumor microenvironments.

Applications

Unspecified application

Species

Unspecified reactive species

Qianqian Cao,Dianshui Sun,Can Tu,Jihua Wang,Runjia Fu,Rumei Gong,Yueying Xiao,Qin Liu,Xiaomei Li
제품이 사용된 논문 모두 보기

Product promise

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