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AB126543

Anti-C1orf192 antibody

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Rabbit Polyclonal C1orf192 antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human CFAP126 aa 100 to C-terminus.
2 이미지
Immunocytochemistry/ Immunofluorescence - Anti-C1orf192 antibody (AB126543)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-C1orf192 antibody (AB126543)

Immunofluorescent staining of Human cell line A-431 shows positivity in cytoplasm. Recommended concentration of ab126543 1-4 µg/ml. Cells treated with PFA/Triton X-100.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C1orf192 antibody (AB126543)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C1orf192 antibody (AB126543)

ab126543, at 1/200 dilution, staining C1orf192 in paraffin-embedded Human stomach tissue by Immunohistochemistry.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P, ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human CFAP126 aa 100 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q5VTH2

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보완 제품

Primary Antibodies

AB126482

Anti-ZCWPW2 antibody

Immunocytochemistry/ Immunofluorescence - Anti-ZCWPW2 antibody (AB126482)

  • 0
  • 0
Primary Antibodies

AB223477

Anti-ZKSCAN3 antibody

Immunocytochemistry/ Immunofluorescence - Anti-ZKSCAN3 antibody (AB223477)

  • 0
  • 0
Primary Antibodies

AB188075

Anti-TCFL5 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TCFL5 antibody (AB188075)

  • 0
  • 0
Primary Antibodies

AB237365

Alexa Fluor® 647 Anti-CD8 alpha antibody [EPR21769]

BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Alexa Fluor® 647 Anti-CD8 alpha antibody [EPR21769] (AB237365)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/200 - 1/500", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1-4 µg/mL", "ICCIF-species-notes": "<p>Recommend PFA Fixation and Triton X-100 treatment</p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

C1orf192 also referred to as Chromosome 1 open reading frame 192 has a molecular mass of approximately 34 kDa. It is expressed in multiple tissues throughout the body but shows higher levels in specific regions like the liver and the brain. Mechanically C1orf192 is hypothesized to function as a binding protein possibly interacting with other proteins to facilitate cellular processes. Its specific domains suggest a role in protein-protein interactions although detailed binding partners and the exact nature of its interactions remain under investigation.
Biological function summary

C1orf192 integrates into cellular functions that are essential for maintaining normal cellular homeostasis. It appears to be involved in regulatory activities though the details of its biological role are still studied. C1orf192 does not seem to be a part of large well-characterized complexes which makes it a harder target for straightforward functional dissection. However ongoing research suggests its potential involvement in modulating cellular signal transduction and possibly influencing cell cycle progression.

Pathways

Our understanding of C1orf192 involves its potential participation in signal transduction and cellular response pathways. It may interact with proteins involved in the AKT signaling pathway which is essential for regulating cell survival and proliferation. While direct interactors in the pathway are not comprehensively established C1orf192 might connect to proteins like PI3K or mTOR suggesting a putative role in these pathways. The exact integration of C1orf192 within these networks requires further experimental validation.

C1orf192 has been linked to neurological conditions suggesting its role in brain-specific functional pathways. Observations connect this target to Alzheimer's Disease where its altered expression might impact disease progression. Furthermore its potential interaction with Beta-amyloid precursor proteins and tau proteins highlights the need to explore its contribution to neurodegenerative mechanisms. Continued studies are important to establish precise causative relationships and therapeutic potentials.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme (PubMed : 36191189). Acts as a regulator of cilium basal body docking and positioning in mono- and multiciliated cells (By similarity). Regulates basal body docking and cilia formation in multiciliated lung cells (By similarity). Regulates kinocilium positioning and stereocilia bundle morphogenesis in the inner ear (By similarity).
See full target information CFAP126

대체 명칭 보기

C1orf192, FLTP, CFAP126, Protein Flattop, Cilia- and flagella-associated protein 126
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Advanced science (Weinheim, Baden-Wurttemberg, Germany) 12:e2403591 PubMed39498824

2024

An EED/PRC2-H19 Loop Regulates Cerebellar Development.

Applications

Unspecified application

Species

Unspecified reactive species

Pei-Pei Liu,Xiao Han,Xiao Li,Shang-Kun Dai,Ya-Jie Xu,Lin-Fei Jiao,Hong-Zhen Du,Li-Hua Zhao,Rong-Feng Li,Zhao-Qian Teng,Yun-Gui Yang,Chang-Mei Liu
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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