JavaScript is disabled in your browser. Please enable JavaScript to view this website.
AB123603

Anti-C1orf77/FOP antibody

Be the first to review this product! 리뷰 제출

|

(1 출판물)

Rabbit Polyclonal C1orf77/FOP antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human CHTOP aa 1-50.

대체 명칭 보기

C1orf77, FOP, HT031, PP7704, CHTOP, Chromatin target of PRMT1 protein, Friend of PRMT1 protein, Small arginine- and glycine-rich protein, SRAG

1 이미지
Western blot - Anti-C1orf77/FOP antibody (AB123603)
  • WB

Unknown

Western blot - Anti-C1orf77/FOP antibody (AB123603)

All lanes:

Western blot - Anti-C1orf77/FOP antibody (ab123603) at 0.4 µg/mL

Lane 1:

Whole cell lysate from Jurkat cells at 50 µg

Lane 2:

Whole cell lysate from Jurkat cells at 15 µg

Lane 3:

Whole cell lysate from 293T cells at 50 µg

Lane 4:

Whole cell lysate from HeLa cells at 50 µg

Predicted band size: 26 kDa

true

Exposure time: 30s

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Synthetic Peptide within Human CHTOP aa 1-50. The exact immunogen used to generate this antibody is proprietary information.

Q9Y3Y2

style
left-column

대체품

Primary Antibodies

AB222861

Anti-C1orf77/FOP antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C1orf77/FOP antibody (AB222861)

  • 0
  • 0
Primary Antibodies

AB220086

Anti-C1orf77/FOP antibody

Immunocytochemistry/ Immunofluorescence - Anti-C1orf77/FOP antibody (AB220086)

  • 0
  • 0

보완 제품

Primary Antibodies

AB166630

Anti-Fibrillarin+Fibrillarin-like protein 1 antibody [EPR10823(B)] - Nucleolar Marker

RabMAb|Recombinant|Lab Essentials

Immunocytochemistry/ Immunofluorescence - Anti-Fibrillarin+Fibrillarin-like protein 1 antibody [EPR10823(B)] - Nucleolar Marker (AB166630)

  • 5
  • 2
Primary Antibodies

AB129160

Anti-NXF1 antibody [EPR8009]

RabMAb|Recombinant|Trial Size

Immunocytochemistry/ Immunofluorescence - Anti-NXF1 antibody [EPR8009] (AB129160)

  • 5
  • 2
Primary Antibodies

AB166620

Anti-ERH antibody [EPR10830(B)]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ERH antibody [EPR10830(B)] (AB166620)

  • 0
  • 0
Primary Antibodies

AB131442

Anti-p53 antibody

Lab Essentials

Western blot - Anti-p53 antibody (AB131442)

  • 4
  • 7
style
left-column

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2500", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Chicken": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Chimpanzee": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Dog": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Gorilla": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Guinea pig": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Horse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Orangutan": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Pig": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rabbit": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rhesus monkey": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Turkey": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
style
left-column
style
left-column

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 7 - 8 Preservative: 0.09% Sodium azide Constituents: 99% Tris citrate/phosphate
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
style
left-column
style
left-column
style
left-column

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
style
left-column

타겟 정보

Plays an important role in the ligand-dependent activation of estrogen receptor target genes (PubMed : 19858291). May play a role in the silencing of fetal globin genes (PubMed : 20688955). Recruits the 5FMC complex to ZNF148, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes (By similarity). Plays an important role in the tumorigenicity of glioblastoma cells. Binds to 5-hydroxymethylcytosine (5hmC) and associates with the methylosome complex containing PRMT1, PRMT5, MEP50 and ERH. The CHTOP-methylosome complex associated with 5hmC is recruited to selective sites on the chromosome, where it methylates H4R3 and activates the transcription of genes involved in glioblastomagenesis (PubMed : 25284789).. Required for effective mRNA nuclear export and is a component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. Stimulates DDX39B ATPase and helicase activities. In cooperation with ALYREF/THOC4 enhances NXF1 RNA binding activity (PubMed : 23299939).
See full target information CHTOP
style
left-column

제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Cell death & disease 11:217 PubMed32245975

2020

Cross organelle stress response disruption promotes gentamicin-induced proteotoxicity.

Applications

Unspecified application

Species

Unspecified reactive species

Chinaemere Igwebuike,Julia Yaglom,Leah Huiting,Hui Feng,Joshua D Campbell,Zhiyong Wang,Andrea Havasi,David Pimentel,Michael Y Sherman,Steven C Borkan
제품이 사용된 논문 모두 보기
style
left-column
style
left-column
style
right-column

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com