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AB68528

Anti-C1QL1 antibody

1

(1 리뷰)

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(3 제품이 사용된 논문 )

Mouse Polyclonal C1QL1 antibody. Suitable for WB and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human C1QL1.
1 이미지
Western blot - Anti-C1QL1 antibody (AB68528)
  • WB

Unknown

Western blot - Anti-C1QL1 antibody (AB68528)

All lanes:

Western blot - Anti-C1QL1 antibody (ab68528) at 1/500 dilution

Lane 1:

transfected 293T cell lysate at 25 µg

Lane 2:

non transfected 293T cell lysate at 25 µg

Secondary

All lanes:

Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Predicted band size: 26 kDa

Observed band size: 26 kDa

false

주요 정보

Host species

Mouse

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human C1QL1.

O75973

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보완 제품

Primary Antibodies

AB200684

Anti-BAI3 antibody

Western blot - Anti-BAI3 antibody (AB200684)

  • 0
  • 0
Primary Antibodies

AB97732

Anti-Rac1 antibody

Immunocytochemistry/ Immunofluorescence - Anti-Rac1 antibody (AB97732)

  • 2
  • 1
Proteins & Peptides

AB161187

Recombinant Human C1QL1 protein (GST tag N-Terminus)

SDS-PAGE - Recombinant Human C1QL1 protein (GST tag N-Terminus) (AB161187)

  • 0
  • 0
Primary Antibodies

AB177487

Anti-NeuN antibody [EPR12763] - Neuronal Marker

BOND RX™ Validated|RabMAb|Recombinant|Lab Essentials|20ul selling size|Advanced Validation

Immunohistochemistry (Frozen sections) - Anti-NeuN antibody [EPR12763] - Neuronal Marker (AB177487)

  • 5
  • 76
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
pH: 7.4 Constituents: 91% Water, 8% Sodium chloride, 0.6% Disodium hydrogenorthophosphate, 0.2% Potassium chloride, 0.2% Potassium phosphate monobasic
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

C1QL1 also known as complement C1q-like protein 1 is a member of the C1q protein family. It has an approximate mass of 26 kDa. This protein is primarily expressed in the brain most notably in the cerebellum indicating its role in central nervous system processes. Researchers often investigate C1QL1 because of its structural similarities to complement components despite its distinct function within the neurological context.
Biological function summary

C1QL1 participates in synapse regulation and the maintenance of synaptic plasticity. It forms a part of a larger complex involving several other C1q-like proteins. These complexes contribute to the modulation of synapse formation and pruning by interacting with receptors on post-synaptic neurons. C1QL1's ability to influence synaptic connectivity makes it an important factor in cognitive development and neuroplasticity aspects fundamental to neuronal network adaptations.

Pathways

C1QL1 engages in pathways related to neural development and synaptic signaling. One significant pathway includes the complement cascade where its role diverges from traditional immune functions to support neural development. C1QL1 associates with proteins such as BAFF and APRIL through this pathway. It also plays a part in modulating the Wnt signaling pathway contributing to neuronal positioning and circuitry refinement.

C1QL1 has links to neurological conditions such as autism spectrum disorders and schizophrenia. Its role in synapse formation and plasticity makes it a significant factor in these disorders both characterized by altered synaptic connectivity. Connections to proteins such as NLGN1 and SHANK3 show how alterations in C1QL1 expression or function may lead to disruptions in synaptic balance highlighting its importance in maintaining normal cognitive function.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

May regulate the number of excitatory synapses that are formed on hippocampus neurons. Has no effect on inhibitory synapses (By similarity).
See full target information C1QL1

대체 명칭 보기

C1QRF, CRF, CTRP14, C1QL1, C1q-related factor, C1q and tumor necrosis factor-related protein 14, Complement component 1 Q subcomponent-like 1, C1q/TNF-related protein 14
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제품이 사용된 논문 (3)

Recent publications for all applications. Explore the 전체 목록 and refine your search

The EMBO journal 41:e109187 PubMed35191554

2022

USP33 deubiquitinates and stabilizes HIF-2alpha to promote hypoxia response in glioma stem cells.

Applications

Unspecified application

Species

Unspecified reactive species

Aili Zhang,Zhi Huang,Weiwei Tao,Kui Zhai,Qiulian Wu,Jeremy N Rich,Wenchao Zhou,Shideng Bao

Journal of chemotherapy (Florence, Italy) 33:476-485 PubMed33825671

2021

C1q-like 1 is frequently up-regulated in lung adenocarcinoma and contributes to the proliferation and invasion of tumor cells.

Applications

Unspecified application

Species

Unspecified reactive species

Yu-Jun Gao,Feng Chen,Lian-Jun Zhang

Cells 9: PubMed32635226

2020

Identification of Novel Molecular Markers of Human Th17 Cells.

Applications

Unspecified application

Species

Unspecified reactive species

Anna Sałkowska,Kaja Karaś,Iwona Karwaciak,Aurelia Walczak-Drzewiecka,Mariusz Krawczyk,Marta Sobalska-Kwapis,Jarosław Dastych,Marcin Ratajewski
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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