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AB235404

Anti-C5orf24 antibody

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Rabbit Polyclonal C5orf24 antibody. Suitable for WB, IHC-P and reacts with Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human UPF0461 protein C5orf24 aa 1-200.

대체 명칭 보기

UPF0461 protein C5orf24, C5orf24

1 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C5orf24 antibody (AB235404)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C5orf24 antibody (AB235404)

Paraffin-embedded human kidney tissue stained for C5orf24 using ab235404 at 1/100 dilution in immunohistochemical analysis.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human UPF0461 protein C5orf24 aa 1-200. The exact immunogen used to generate this antibody is proprietary information.

Q7Z6I8

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보완 제품

Primary Antibodies

AB155675

Anti-CPNE1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CPNE1 antibody (AB155675)

  • 0
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Primary Antibodies

AB259950

Anti-Calcium-independent Phospholipase A2/PLA2G6 antibody [EPR23994-103]

BOND RX™ Validated|KO Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Calcium-independent Phospholipase A2/PLA2G6 antibody [EPR23994-103] (AB259950)

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  • 0
Primary Antibodies

AB108994

Anti-Stromal interaction molecule 1 antibody [EPR3414]

20ul selling size|RabMAb|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Stromal interaction molecule 1 antibody [EPR3414] (AB108994)

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  • 1
Primary Antibodies

AB96774

Anti-Epoxide hydrolase antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Epoxide hydrolase antibody (AB96774)

  • 3
  • 1
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
Purification 관련 사항
Purity >95%
보관 버퍼
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

C5orf24 also known as Chromosome 5 open reading frame 24 is a protein with a molecular weight of approximately 54 kDa. This protein is expressed in various tissues but shows higher expression levels in the brain and liver suggesting its importance in these organs. The mechanical function of C5orf24 involves interactions with other cellular components though exact binding partners are still under investigation. Current research indicates potential involvement in cellular signaling or maintenance functions.
Biological function summary

The function of Chromosome 5 open reading frame 24 involves regulatory roles within the cell. Although not yet confirmed as part of a larger complex C5orf24 may participate in cellular processes such as proliferation and differentiation based on its expression pattern and interactions. These processes hint at a role in overall cellular health and development aligning with its presence in vital tissues like the brain and liver.

Pathways

Protein C5orf24 is implicated in essential signaling pathways including the PI3K/AKT pathway which influences cell survival and growth. This pathway is critical for transmitting signals from various growth factors and cytokines. Additionally C5orf24 might interact with proteins such as AKT and mTOR which are key players in cellular metabolism and growth regulation. This involvement in major pathways points to its potential as a modulatory protein within complex cellular networks.

Research suggests that Chromosome 5 open reading frame 24 could have links to neurodegenerative diseases like Alzheimer's disease. Altered expression levels of C5orf24 in the brain may contribute to disease progression through its interaction with proteins such as Tau which is associated with neurofibrillary tangles. Furthermore C5orf24 may play a role in liver diseases possibly connected to disrupted cellular stress responses linking it with pathways involving proteins like ATF6 a regulator in the unfolded protein response.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

See full target information UPF0461 protein C5orf24
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

iScience 26:106468 PubMed37091236

2023

Latent CSN-CRL complexes are crucial for curcumin-induced apoptosis and recruited during adipogenesis to lipid droplets via small GTPase RAB18.

Applications

Unspecified application

Species

Unspecified reactive species

Dawadschargal Dubiel,Jing Wang,Roland Hartig,Supattra Chaithongyot,Wolfgang Dubiel,Michael Naumann
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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