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AB235086

Anti-C8ORF34 antibody

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Rabbit Polyclonal C8ORF34 antibody. Suitable for WB, IHC-P and reacts with Mouse, Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human C8orf34 aa 1-300.

대체 명칭 보기

Uncharacterized protein C8orf34, Protein VEST-1, C8orf34

2 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C8ORF34 antibody (AB235086)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C8ORF34 antibody (AB235086)

Paraffin-embedded human skin tissue stained for C8ORF34 using ab235086 at 1/100 dilution in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C8ORF34 antibody (AB235086)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-C8ORF34 antibody (AB235086)

Paraffin-embedded human thyroid tissue stained for C8ORF34 using ab235086 at 1/100 dilution in immunohistochemical analysis.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

IHC-P, WB

applications

Immunogen

Recombinant Fragment Protein within Human C8orf34 aa 1-300. The exact immunogen used to generate this antibody is proprietary information.

Q49A92

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보완 제품

Primary Antibodies

AB235046

Anti-WDR37 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-WDR37 antibody (AB235046)

  • 0
  • 0
Primary Antibodies

AB237532

Anti-SPTLC3 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SPTLC3 antibody (AB237532)

  • 0
  • 0
Primary Antibodies

AB234981

Anti-GNPNAT1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GNPNAT1 antibody (AB234981)

  • 0
  • 0
Primary Antibodies

AB185546

Anti-WAVE 1 antibody [EPR15021] - N-terminal

RabMAb|Recombinant

Flow Cytometry (Intracellular) - Anti-WAVE 1 antibody [EPR15021] - N-terminal (AB185546)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/5000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
Purification 관련 사항
Purity >95%
보관 버퍼
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

The protein C8ORF34 also known as Chromosome 8 Open Reading Frame 34 is a relatively lesser-known component with a mass of approximately 30 kDa. The gene encoding C8ORF34 is expressed in several tissues including the brain liver and heart. Although the precise mechanical function of C8ORF34 remains under investigation initial studies suggest it might play a role in cellular homeostasis. Expression profiling reveals significant presence in both embryonic and adult tissues adding complexity to its functional understanding.
Biological function summary

The function of C8ORF34 in cells appears linked to mitochondrial processes. While it is still not clear if C8ORF34 acts as a part of a larger protein complex some evidence points towards its potential interactions with mitochondrial proteins. C8ORF34 may have roles that impact energy production and metabolic regulation. Further research is needed to fully uncover how C8ORF34 operates within the mitochondria.

Pathways

C8ORF34 seems important in pathways involving mitochondrial dynamics and apoptosis. Initial data have suggested that its interaction with proteins like BCL-2 and BAX indicates a relevance to the apoptosis pathway. These interactions point to a possible regulatory role that affects cellular responses to stress and survival. Understanding C8ORF34's exact pathway integrations will require more detailed pathway mapping.

Research on C8ORF34 is still emerging. However recent studies have pointed toward a potential link to neurodegenerative diseases such as Alzheimer's Disease. Disrupted mitochondrial function associated with C8ORF34 offers a connection to this disorder alongside proteins like APP and Tau. Another area of concern involves metabolic syndromes although more studies are needed to confirm these associations. The connections in these disorders invite exploration into therapeutic targeting of C8ORF34.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

See full target information C8orf34
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Nature communications 14:3729 PubMed37349316

2023

Maternal NAT10 orchestrates oocyte meiotic cell-cycle progression and maturation in mice.

Applications

Unspecified application

Species

Unspecified reactive species

Xue Jiang,Yu Cheng,Yuzhang Zhu,Caoling Xu,Qiaodan Li,Xuemei Xing,Wenqing Li,Jiaqi Zou,Lan Meng,Muhammad Azhar,Yuzhu Cao,Xianhong Tong,Weibing Qin,Xiaoli Zhu,Jianqiang Bao
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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