AB134137

Anti-cadherin 10 antibody [EPR5115]

RabMAb
Recombinant
각 태그의 뜻

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(3 제품이 사용된 논문 )

Rabbit Recombinant Monoclonal cadherin 10 antibody. Suitable for WB, Flow Cyt (Intra) and reacts with Human, Mouse, Rat samples. Cited in 3 publications.

대체 명칭 보기

Cadherin-10, T2-cadherin, CDH10

2 이미지

Flow Cytometry (Intracellular) - Anti-cadherin 10 antibody [EPR5115] (AB134137)

Flow Cyt (Intra)

Unknown

Flow Cytometry (Intracellular) - Anti-cadherin 10 antibody [EPR5115] (AB134137)

Intracellular flow cytometric analysis of permeabilised U-87 MG cells labelling cadherin 10 with ab134137 at 1/10 dilution (red) or rabbit IgG negative (green).

Unknown

Western blot - Anti-cadherin 10 antibody [EPR5115] (AB134137)

The expression profile observed is consistent with what has been described in the literature PMID : 16181616

All lanes:

Western blot - Anti-cadherin 10 antibody [EPR5115] (ab134137) at 1/1000 dilution

Lane 1:

Human fetal brain lysate at 10 µg

Lane 2:

U-87 MG lysate at 10 µg

Lane 3:

Human fetal lung lysate at 10 µg

Secondary

All lanes:

Goat Anti-rabbit HRP at 1/2000 dilution

Predicted band size: 88 kDa

Observed band size: 115-130 kDa

false

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR5115

Isotype

IgG

Carrier free

Reacts with

Human

Applications

WB, Flow Cyt (Intra)

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "FlowCytIntra" : {"fullname" : "Flow Cytometry (Intracellular)", "shortname":"Flow Cyt (Intra)"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "testedAndGuaranteed", "FlowCytIntra-species-dilution-info": "1/10 - 1/100", "FlowCytIntra-species-notes": "<a href='/ko/products/primary-antibodies/rabbit-igg-monoclonal-epr25a-isotype-control-ab172730'>ab172730</a> - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody." }, "Mouse": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "predicted", "FlowCytIntra-species-dilution-info": "", "FlowCytIntra-species-notes": "" }, "Rat": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "FlowCytIntra-species-checked": "predicted", "FlowCytIntra-species-dilution-info": "", "FlowCytIntra-species-notes": "" } } }

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제품 세부 정보

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Protein A

보관 버퍼

pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

배송 시 보관 조건

Conditional Ambient

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Cadherin-10 often referred to as CDH10 is a member of the classical cadherin family which are vital components of calcium-dependent cell-cell adhesion. This protein is approximately 98 kDa in mass. CDH10 is expressed widely in the central nervous system and is also present in other tissues such as the pancreas and kidney. The cadherin family plays a significant role in mediating homophilic interactions between cells influencing tissue architecture and integrity.

Biological function summary

Cadherin-10 assists in maintaining precise cellular recognition and adhesion. It is particularly involved in the development and maintenance of neural circuits suggesting its involvement in the complexity of brain network formation. Cadherin-10 operates as part of adhesion complexes interacting with cytoplasmic components that link to the actin cytoskeleton thereby influencing cell signaling pathways and cellular communication.

Pathways

Cadherin-10 contributes significantly to the Wnt signaling pathway and adherens junction pathways. These pathways are critical for processes such as cellular differentiation migration and organization. Cadherin-10 has related interactions with proteins like beta-catenin within these pathways which facilitates signal transduction and cell structural integrity.

Alterations in cadherin-10 can affect neurological and developmental conditions. Mutations or dysregulation of CDH10 have associations with autism spectrum disorders impacting neural communication genes. Similarly changes in cadherin-10 expressions also show connections to manic disorders implying a role in emotional regulation pathways linked to neuropsychiatric proteins such as N-cadherin and synaptic adhesion molecules.

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.

See full target information CDH10

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제품이 사용된 논문 (3)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Theranostics 15:3627-3642 PubMed40093901

2025

Circular RNA CHACR is involved in the pathogenesis of cardiac hypertrophy.

Applications

Unspecified application

Species

Unspecified reactive species

Lili Chen,Wenjing Wang,Yiheng Zhao,Shuchen Zhang,Xiang Zhou

CNS neuroscience & therapeutics 31:e70257 PubMed39915908

2025

Caloric Restriction Preserves BBB Integrity After Transient Focal Cerebral Ischemia Through Reducing Neutrophil Infiltration.

Applications

Unspecified application

Species

Unspecified reactive species

Chenran Wang,Leilei Mao,Miao He,Jia Zhang,Yichen Huang,Yue Zhang,Jing Xu,Shaoqiang Huang,Yanqin Gao

The European journal of neuroscience 49:1436-1453 PubMed30589479

2019

A Sam68-dependent alternative splicing program shapes postsynaptic protein complexes.

Applications

Unspecified application

Species

Unspecified reactive species

Harald Witte,Dietmar Schreiner,Peter Scheiffele

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-cadherin 10 antibody [EPR5115]

Flow Cytometry (Intracellular) - Anti-cadherin 10 antibody [EPR5115] (AB134137)

Western blot - Anti-cadherin 10 antibody [EPR5115] (AB134137)

관련 conjugated 항체와 다양한 조성의 항체 (1)

주요 정보

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

보완 제품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

제품 세부 정보

특성 및 보관 정보

제형

Purification 테크닉

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 조건

적절한 장기 보관 조건

추가 정보

Biological function summary

Pathways

제품 프로토콜

타겟 정보

제품이 사용된 논문 (3)

Product promise