AB2860

Anti-Calmodulin 1/2/3 antibody [2D1]

Name: Anti-Calmodulin 1/2/3 antibody [2D1]
Brand: Abcam Limited
SKU: AB2860
Rating: 1 (1 reviews)

(1 리뷰)

(18 제품이 사용된 논문 )

Mouse Monoclonal CALM1 antibody. Suitable for Flow Cyt, IHC-P, WB, ELISA, IP, ICC/IF and reacts with Human, Rat, Dictyostelium discoideum, Mouse, Chicken, Cow samples. Cited in 18 publications.

대체 명칭 보기

CALM, CAM, CAM1, CALM1, Calmodulin-1, CALML2, CAM3, CAMC, CAMIII, CALM3, Calmodulin-3, CAM2, CAMB, CALM2, Calmodulin-2

10 이미지

Immunocytochemistry/ Immunofluorescence - Anti-Calmodulin 1/2/3 antibody [2D1] (AB2860)

ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-Calmodulin 1/2/3 antibody [2D1] (AB2860)

Immunofluorescent analysis of HeLa (Human epithelial cell line from cervix adenocarcinoma) cells labeling Calmodulin with ab2860. Calmodulin staining (green) F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with or an antibody recognizing Calmodulin ab2860 at a dilution of 1 : 50 over night at 4 °C washed with PBS and incubated with a DyLight-488 conjugated secondary antibody. Images were taken at 60X magnification.

Flow Cytometry - Anti-Calmodulin 1/2/3 antibody [2D1] (AB2860)

Flow Cyt

Lab

Flow Cytometry - Anti-Calmodulin 1/2/3 antibody [2D1] (AB2860)

Overlay histogram showing HeLa cells stained with ab2860 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab2860, 2μg/1x10⁶ cells) for 30 min at 22°C. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 2μg/1x10⁶ cells ) used under the same conditions. Acquisition of >5,000 events was performed.

ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-Calmodulin 1/2/3 antibody [2D1] (AB2860)

Immunofluorescent analysis of A2058 (Human metastatic melanoma cell line) cells labeling Calmodulin ab2860. Calmodulin staining (green) F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with or an antibody recognizing Calmodulin ab2860 at a dilution of 1 : 50 over night at 4 °C washed with PBS and incubated with a DyLight-488 conjugated secondary antibody. Images were taken at 60X magnification.

Flow Cyt

Supplier Data

Flow Cytometry - Anti-Calmodulin 1/2/3 antibody [2D1] (AB2860)

Flow cytometry analysis of Calmodulin showing positive staining in the cytoplasm of MCF7 (Human breast adenocarcinoma cell line) cells compared to an isotype control (blue). Cells were harvested and adjusted to a concentration of 1-5x10^6 cells/ml. Cells were then fixed with 2% paraformaldehyde and washed with PBS. Cells were penetrated by dropping the supernatant and adding 90% methanol followed by incubation for 10 minutes at room temperature. Cells were blocked with a 2% solution of BSA-PBS for 30 min at room temperature and incubated with ab2860 at a dilution of 2 ug/test for 60 min at room temperature. Cells were then incubated for 40 min at room temperature in the dark using a Dylight 488-conjugated goat anti-mouse IgG (H+L) secondary antibody and re-suspended in PBS for FACS analysis.

Flow Cyt

Unknown

Flow Cytometry - Anti-Calmodulin 1/2/3 antibody [2D1] (AB2860)

Flow cytometry analysis of Calmodulin showing positive staining in the cytoplasm of PC-12 (Rat adrenal gland pheochromocytoma cell line) cells compared to an isotype control (blue). Cells were harvested and adjusted to a concentration of 1-5x10^6 cells/ml. Cells were then fixed with 2% paraformaldehyde and washed with PBS. Cells were penetrated by dropping the supernatant and adding 90% methanol followed by incubation for 10 minutes at room temperature. Cells were blocked with a 2% solution of BSA-PBS for 30 min at room temperature and incubated with ab2860 at 2 ug/test for 60 min at room temperature. Cells were then incubated for 40 min at room temperature in the dark using a Dylight 488-conjugated goat anti-mouse IgG (H+L) secondary antibody and re-suspended in PBS for FACS analysis.

ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-Calmodulin 1/2/3 antibody [2D1] (AB2860)

Immunofluorescent analysis of C6 (Rat glial tumor cell line) cells labeling Calmodulin ab2860. Calmodulin staining (green) F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with or an antibody recognizing Calmodulin ab2860 at a dilution of 1 : 50 over night at 4 °C washed with PBS and incubated with a DyLight-488 conjugated secondary antibody. Images were taken at 60X magnification.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Calmodulin 1/2/3 antibody [2D1] (AB2860)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Calmodulin 1/2/3 antibody [2D1] (AB2860)

Immunohistochemistry was performed on normal biopsies of deparaffinized rat cerebellum tissue. To expose target proteins heat induced antigen retrieval was performed using 10mM sodium citrate (pH6.0) buffer microwaved for 8-15 minutes. Following antigen retrieval tissues were blocked in 3% BSA-PBS for 30 minutes at room temperature. Tissues were then probed at a dilution of 1 : 20 with a mouse monoclonal antibody recognizing Calmodulin ab2860 or without primary antibody (negative control) overnight at 4°C in a humidified chamber. Tissues were washed extensively with PBST and endogenous peroxidase activity was quenched with a peroxidase suppressor. Detection was performed using a biotin-conjugated secondary antibody and SA-HRP followed by colorimetric detection using DAB. Tissues were counterstained with hematoxylin and prepped for mounting.

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Calmodulin 1/2/3 antibody [2D1] (AB2860)

Immunohistochemistry was performed on normal biopsies of deparaffinized rat testis tissue. To expose target proteins heat induced antigen retrieval was performed using 10mM sodium citrate (pH6.0) buffer microwaved for 8-15 minutes. Following antigen retrieval tissues were blocked in 3% BSA-PBS for 30 minutes at room temperature. Tissues were then probed at a dilution of 1 : 20 with a mouse monoclonal antibody recognizing Calmodulin ab2860 or without primary antibody (negative control) overnight at 4°C in a humidified chamber. Tissues were washed extensively with PBST and endogenous peroxidase activity was quenched with a peroxidase suppressor. Detection was performed using a biotin-conjugated secondary antibody and SA-HRP followed by colorimetric detection using DAB. Tissues were counterstained with hematoxylin and prepped for mounting.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Calmodulin 1/2/3 antibody [2D1] (AB2860)

Immunolocalization of calmodulin in rat brain cells using ab2860 (1 : 100)

Flow Cyt

Supplier Data

Flow Cytometry - Anti-Calmodulin 1/2/3 antibody [2D1] (AB2860)

Flow cytometry analysis of Calmodulin showing positive staining in the cytoplasm of C6 (Rat glial tumor cell line) cells compared to an isotype control (blue). Cells were harvested and adjusted to a concentration of 1-5x10^6 cells/ml. Cells were then fixed with 2% paraformaldehyde and washed with PBS. Cells were penetrated by dropping the supernatant and adding 90% methanol followed by incubation for 10 minutes at room temperature. Cells were blocked with a 2% solution of BSA-PBS for 30 min at room temperature and incubated with ab2860 at 2 ug/test for 60 min at room temperature. Cells were then incubated for 40 min at room temperature in the dark using a Dylight 488-conjugated goat anti-mouse IgG (H+L) secondary antibody and re-suspended in PBS for FACS analysis.

주요 정보

Host species

Mouse

Clonality

Monoclonal

Clone number

2D1

Isotype

IgG1

Carrier free

Reacts with

Rat, Human, Mouse, Cow, Dictyostelium discoideum, Chicken

Applications

ICC/IF, Flow Cyt, WB, IHC-P, ELISA, IP

applications

Specificity

This antibody detects calmodulin. It does not detect parvalbumin, tropinin, S-100, or myosin light chain kinase (MLCK).By Western blot, this antibody detects a 17 kDa protein representing calmodulin from Dictyostelium cell lysate. Immunohistochemical staining of calmodulin in Dictyostelium cells with this antibody results in staining of the contractile vacuoles.

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ELISA" : {"fullname" : "ELISA", "shortname":"ELISA"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "2 µg for 10^6 Cells", "FlowCyt-species-notes": "Diution is only suitable for human reaction.<a href='/ko/products/primary-antibodies/mouse-igg1-kappa-monoclonal-15-6e10a7-isotype-control-ab170190'>ab170190</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "1/20 - 1/100", "IHCP-species-notes": " Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/50", "ICCIF-species-notes": "" }, "Mouse": { "FlowCyt-species-checked": "guaranteed", "FlowCyt-species-dilution-info": "2 µg for 10^6 Cells", "FlowCyt-species-notes": "Diution is only suitable for human reaction.<a href='/ko/products/primary-antibodies/mouse-igg1-kappa-monoclonal-15-6e10a7-isotype-control-ab170190'>ab170190</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "1/50", "ICCIF-species-notes": "" }, "Rat": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "2 µg for 10^6 Cells", "FlowCyt-species-notes": "Diution is only suitable for human reaction.<a href='/ko/products/primary-antibodies/mouse-igg1-kappa-monoclonal-15-6e10a7-isotype-control-ab170190'>ab170190</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/100", "IHCP-species-notes": " Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/50", "ICCIF-species-notes": "" }, "Chicken": { "FlowCyt-species-checked": "guaranteed", "FlowCyt-species-dilution-info": "2 µg for 10^6 Cells", "FlowCyt-species-notes": "Diution is only suitable for human reaction.<a href='/ko/products/primary-antibodies/mouse-igg1-kappa-monoclonal-15-6e10a7-isotype-control-ab170190'>ab170190</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "1/20 - 1/100", "IHCP-species-notes": " Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "1/50", "ICCIF-species-notes": "" }, "Cow": { "FlowCyt-species-checked": "guaranteed", "FlowCyt-species-dilution-info": "2 µg for 10^6 Cells", "FlowCyt-species-notes": "Diution is only suitable for human reaction.<a href='/ko/products/primary-antibodies/mouse-igg1-kappa-monoclonal-15-6e10a7-isotype-control-ab170190'>ab170190</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "1/20 - 1/100", "IHCP-species-notes": " Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "1/50", "ICCIF-species-notes": "" }, "Dictyostelium discoideum": { "FlowCyt-species-checked": "guaranteed", "FlowCyt-species-dilution-info": "2 µg for 10^6 Cells", "FlowCyt-species-notes": "Diution is only suitable for human reaction.<a href='/ko/products/primary-antibodies/mouse-igg1-kappa-monoclonal-15-6e10a7-isotype-control-ab170190'>ab170190</a> - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.", "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "1/20 - 1/100", "IHCP-species-notes": " Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "guaranteed", "WB-species-dilution-info": "1/500", "WB-species-notes": "", "ELISA-species-checked": "guaranteed", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "IP-species-checked": "guaranteed", "IP-species-dilution-info": "", "IP-species-notes": "", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "1/50", "ICCIF-species-notes": "" }, "Wheat": { "FlowCyt-species-checked": "predicted", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ELISA-species-checked": "predicted", "ELISA-species-dilution-info": "", "ELISA-species-notes": "", "IP-species-checked": "predicted", "IP-species-dilution-info": "", "IP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Protein A

보관 버퍼

Preservative: 0.05% Sodium azide Constituents: PBS

배송 시 보관 조건

Blue Ice

적절한 단기 보관 기간

1-2 weeks

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Calmodulin also known as calmoduline is a multifunctional intermediate calcium-binding protein expressed widely in eukaryotic cells. This small protein has a molecular weight of approximately 16.7 kDa. Calmodulin 1 2 and 3 serve as the key isoforms facilitating a variety of calcium-mediated processes. You can find it in cellular contexts where calcium signaling plays a regulatory role. Due to its ubiquity it acts as a mediator in numerous cellular responses.

Biological function summary

Calmodulin modulates intracellular activities by binding to calcium ions and interacting with a wide array of target proteins. It is not part of a molecular complex but can partner with proteins like kinases and phosphatases leading to downstream effects on diverse cellular processes. Calmodulin function extends to muscle contraction cell division and signal transduction impacting both basal and specialized cellular functions.

Pathways

Calmodulin operates as a functional link in calcium signaling and the MAPK signaling pathways. In these pathways calmodulin influences the activity of proteins such as myosin light-chain kinase and calmodulin-dependent protein kinase. These interactions showcase calmodulin's pivotal role in translating calcium signaling into cellular responses connecting several signaling cascades.

Calmodulin has associations with certain cardiovascular diseases and neurodegenerative conditions. Its relationship with ion channel dysfunction links it to disorders like long QT syndrome. Additionally calmodulin interacts with proteins like sodium-calcium exchangers or other ion-handling channels reflecting its involvement in maintaining cellular ionic balance and consequently its implication in pathological states when dysregulated.

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding (PubMed : 16760425, PubMed : 23893133, PubMed : 26969752, PubMed : 27165696, PubMed : 28890335, PubMed : 31454269, PubMed : 35568036). Calcium-binding is required for the activation of calmodulin (PubMed : 16760425, PubMed : 23893133, PubMed : 26969752, PubMed : 27165696, PubMed : 28890335, PubMed : 31454269, PubMed : 35568036). Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases, such as myosin light-chain kinases and calmodulin-dependent protein kinase type II (CaMK2), and phosphatases (PubMed : 16760425, PubMed : 23893133, PubMed : 26969752, PubMed : 27165696, PubMed : 28890335, PubMed : 31454269, PubMed : 35568036). Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (PubMed : 16760425). Is a regulator of voltage-dependent L-type calcium channels (PubMed : 31454269). Mediates calcium-dependent inactivation of CACNA1C (PubMed : 26969752). Positively regulates calcium-activated potassium channel activity of KCNN2 (PubMed : 27165696). Forms a potassium channel complex with KCNQ1 and regulates electrophysiological activity of the channel via calcium-binding (PubMed : 25441029). Acts as a sensor to modulate the endoplasmic reticulum contacts with other organelles mediated by VMP1 : ATP2A2 (PubMed : 28890335).. (Microbial infection) Required for Legionella pneumophila SidJ glutamylase activity.. (Microbial infection) Required for C.violaceum CopC and S.flexneri OspC3 arginine ADP-riboxanase activity.

See full target information CALM1

Additional targets

,CALM3

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제품이 사용된 논문 (18)

Recent publications for all applications. Explore the 전체 목록 and refine your search

NPJ science of food 9:178 PubMed40826004

2025

Effects of Mytilus edulis derived plasmalogens against atherosclerosis via lipid metabolism and MAPK signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Junli Feng,Jian Zhang,Shitong Wang,Zhenwei Li,Hong Yuan,Haiming Yao,Jing Xue,Jing Zheng,Yeshun Wu,Siwei Wang,Xixi Zeng,Yong Cui,Oushan Tang,Keyun Cheng,Qing Shen

Glia 73:2057-2076 PubMed40631759

2025

SUR1-TRPM4 Regulates Aquaporin-4 Subcellular Localization by Astrocytic Endfeet Calcium Signals Following Status Epilepticus.

Applications

Unspecified application

Species

Unspecified reactive species

Tingting Yang,Zhenzhou Lin,Mingjia Yu,Yongchuan Li,Jiancong Chen,Yuanchi Liu,Kaibin Huang,Suyue Pan

Cell death & disease 15:429 PubMed38890273

2024

Tau disengages from the proteosome core complex and neurogranin coincident with enhanced neuronal network excitability.

Applications

Unspecified application

Species

Unspecified reactive species

Katriona L Hole,Bangfu Zhu,Laura Huggon,Jon T Brown,Jody M Mason,Robert J Williams

iScience 27:109156 PubMed38439960

2024

Trifluoperazine regulates blood-brain barrier permeability via the MLCK/p-MLC pathway to promote ischemic stroke recovery.

Applications

Unspecified application

Species

Unspecified reactive species

Wentao Zhang,Sisi Chen,Bin Ma,Yingmei Ding,Xiaofen Liu,Caijun He,Biao Wang,Mei Yuan

EMBO molecular medicine 14:e16501 PubMed36321563

2022

IQCN disruption causes fertilization failure and male infertility due to manchette assembly defect.

Applications

Unspecified application

Species

Unspecified reactive species

Jing Dai,Qi Li,Qinwei Zhou,Shen Zhang,Junru Chen,Yize Wang,Jing Guo,Yifan Gu,Fei Gong,Yueqiu Tan,Guangxiu Lu,Wei Zheng,Ge Lin

Cells 11: PubMed35456008

2022

Calreticulin Shortage Results in Disturbance of Calcium Storage, Mitochondrial Disease, and Kidney Injury.

Applications

Unspecified application

Species

Unspecified reactive species

Asima Tayyeb,Gry H Dihazi,Björn Tampe,Michael Zeisberg,Desiree Tampe,Samy Hakroush,Charlotte Bührig,Jenny Frese,Nazli Serin,Marwa Eltoweissy,Gerhard A Müller,Hassan Dihazi

International journal of molecular sciences 23: PubMed35269623

2022

Further Evidence of the Melatonin Calmodulin Interaction: Effect on CaMKII Activity.

Applications

Unspecified application

Species

Unspecified reactive species

Jesús Argueta,Héctor Solís-Chagoyán,Rosa Estrada-Reyes,Luis A Constantino-Jonapa,Julián Oikawa-Sala,Javier Velázquez-Moctezuma,Gloria Benítez-King

Heliyon 7:e07503 PubMed34401557

2021

extract attenuates staurosporine induced neurotoxicity by restoring the FGF2-PI3K/Akt signaling axis and Dnmt3.

Applications

Unspecified application

Species

Unspecified reactive species

Zhe-Ping Cai,Chang Cao,Zhe Guo,Yun Yu,Si-Jia Zhong,Rui-Yuan Pan,Haowen Liang,Rongfeng Lan,Xiao-Yan Qin

Scientific reports 9:12876 PubMed31578341

2019

Synthetic PreImplantation Factor (sPIF) induces posttranslational protein modification and reverses paralysis in EAE mice.

Applications

Unspecified application

Species

Unspecified reactive species

Soren Hayrabedyan,Reut Shainer,Zhanna Yekhtin,Lola Weiss,Osnat Almogi-Hazan,Reuven Or,Charles L Farnsworth,Scott Newsome,Krassimira Todorova,Michael J Paidas,Chaya Brodie,Eytan R Barnea,Martin Mueller

Antioxidants & redox signaling 30:542-559 PubMed29486586

2018

Single-Cell Transcriptomics of Human Oocytes: Environment-Driven Metabolic Competition and Compensatory Mechanisms During Oocyte Maturation.

Applications

Unspecified application

Species

Unspecified reactive species

Hongcui Zhao,Tianjie Li,Yue Zhao,Tao Tan,Changyu Liu,Yali Liu,Liang Chang,Ning Huang,Chang Li,Yong Fan,Yang Yu,Rong Li,Jie Qiao

제품이 사용된 논문 모두 보기

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Product promise

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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Calmodulin 1/2/3 antibody [2D1]

Immunocytochemistry/ Immunofluorescence - Anti-Calmodulin 1/2/3 antibody [2D1] (AB2860)

Flow Cytometry - Anti-Calmodulin 1/2/3 antibody [2D1] (AB2860)

Immunocytochemistry/ Immunofluorescence - Anti-Calmodulin 1/2/3 antibody [2D1] (AB2860)

Flow Cytometry - Anti-Calmodulin 1/2/3 antibody [2D1] (AB2860)

Flow Cytometry - Anti-Calmodulin 1/2/3 antibody [2D1] (AB2860)

Immunocytochemistry/ Immunofluorescence - Anti-Calmodulin 1/2/3 antibody [2D1] (AB2860)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Calmodulin 1/2/3 antibody [2D1] (AB2860)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Calmodulin 1/2/3 antibody [2D1] (AB2860)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Calmodulin 1/2/3 antibody [2D1] (AB2860)

Flow Cytometry - Anti-Calmodulin 1/2/3 antibody [2D1] (AB2860)

주요 정보

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Specificity

대체품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

보완 제품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 기간

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

추가 정보

Biological function summary

Pathways

제품 프로토콜

타겟 정보

Additional targets

제품이 사용된 논문 (18)

Product promise