AB64829

Anti-Casein Kinase 1 gamma 2 antibody

Name: Anti-Casein Kinase 1 gamma 2 antibody
Brand: Abcam Limited
SKU: AB64829
Rating: 3 (1 reviews)

(1 리뷰)

(6 제품이 사용된 논문 )

Rabbit Polyclonal Casein Kinase 1 gamma 2 antibody. Suitable for WB and reacts with Human samples. Cited in 6 publications. Immunogen corresponding to Synthetic Peptide within Human CSNK1G2.

2 이미지

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Western blot - Anti-Casein Kinase 1 gamma 2 antibody (AB64829)

All lanes:

Western blot - Anti-Casein Kinase 1 gamma 2 antibody (ab64829) at 1/500 dilution

Lane 1:

HeLa cell extract at 30 µg

Lane 2:

293 cell extract at 30 µg

Lane 3:

293 cell extract at 30 µg with immunising peptide

Predicted band size: 47 kDa

Observed band size: 25 kDa,34 kDa,47 kDa

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AbReview32952****

Western blot - Anti-Casein Kinase 1 gamma 2 antibody (AB64829)

Lanes 1 - 2:

Anti-Casein Kinase 1 gamma 2 antibody (<a href='/ko/products/unavailable/casein-kinase-1-gamma-2-antibody-ab102554'>ab102554</a>)

Lanes 3 - 4:

Anti-Casein Kinase 1 gamma 2 antibody (<a href='/ko/products/unavailable/casein-kinase-1-gamma-2-antibody-ab70862'>ab70862</a>)

Lanes 5 - 6:

Western blot - Anti-Casein Kinase 1 gamma 2 antibody (ab64829) at 1/500 dilution

Lanes 1, 3 and 5:

U2OS cells expressing FLAG-tagged CK1G2 plasmid

Lane 2:

U2OS cells expressing FLAG tag only plasmid

Lanes 4 and 6:

U2OS cells expressing FLAG only

Secondary

All lanes:

HRP-conjugated Goat anti-rabbit polyclonal at 1/1000 dilution

Predicted band size: 47 kDa

true

This image is courtesy of an anonymous Abreview

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

applications

Immunogen

Synthetic Peptide within Human CSNK1G2. The exact immunogen used to generate this antibody is proprietary information.

P78368

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/1000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Immunogen

보관 버퍼

pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride

배송 시 보관 조건

Blue Ice

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

보관 정보

Stable for 12 months at -20°C

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling (By similarity). Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses. Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis. Triggers PER1 proteasomal degradation probably through phosphorylation (PubMed : 15077195, PubMed : 15917222, PubMed : 18794808, PubMed : 19005213). Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate (By similarity). Involved in regulation of reactive oxygen species (ROS) levels (PubMed : 37099597).

See full target information CSNK1G2

대체 명칭 보기

CK1G2, CSNK1G2, Casein kinase I isoform gamma-2, CKI-gamma 2

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제품이 사용된 논문 (6)

Recent publications for all applications. Explore the 전체 목록 and refine your search

The Journal of biological chemistry 298:101986 PubMed35487243

2022

Protein proximity networks and functional evaluation of the casein kinase 1 gamma family reveal unique roles for CK1γ3 in WNT signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Megan J Agajanian,Frances M Potjewyd,Brittany M Bowman,Smaranda Solomon,Kyle M LaPak,Dhaval P Bhatt,Jeffery L Smith,Dennis Goldfarb,Alison D Axtman,Michael B Major

Molecular medicine reports 17:7559-7566 PubMed29620268

2018

Induction of Huh‑7 cell apoptosis by HCV core proteins via CK1α‑p53‑Bid signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Shanshan Shen,Chunyang Li,Mingjia Dai,Xuebing Yan

Proceedings of the National Academy of Sciences of 114:7148-7153 PubMed28533369

2017

Phosphorylated Presenilin 1 decreases β-amyloid by facilitating autophagosome-lysosome fusion.

Applications

Species

Mouse

Victor Bustos,Maria V Pulina,Ashley Bispo,Alison Lam,Marc Flajolet,Fred S Gorelick,Paul Greengard

Oncogene 36:429-438 PubMed27321178

2016

Activation of CK1ɛ by PP2A/PR61ɛ is required for the initiation of Wnt signaling.

Applications

Unspecified application

Species

Human

M Vinyoles,B Del Valle-Pérez,J Curto,M Padilla,A Villarroel,J Yang,A G de Herreros,M Duñach

Molecular and cellular biology 31:2877-88 PubMed21606194

2011

Coordinated action of CK1 isoforms in canonical Wnt signaling.

Applications

Species

Human

Beatriz Del Valle-Pérez,Oriol Arqués,Meritxell Vinyoles,Antonio García de Herreros,Mireia Duñach

Journal of cell science 123:2621-31 PubMed20940130

2010

A p120-catenin-CK1epsilon complex regulates Wnt signaling.

Applications

Species

Human

David Casagolda,Beatriz Del Valle-Pérez,Gabriela Valls,Ero Lugilde,Meritxell Vinyoles,Juan Casado-Vela,Guiomar Solanas,Eduard Batlle,Albert B Reynolds,José Ignacio Casal,Antonio García de Herreros,Mireia Duñach

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Casein Kinase 1 gamma 2 antibody

Western blot - Anti-Casein Kinase 1 gamma 2 antibody (AB64829)

Western blot - Anti-Casein Kinase 1 gamma 2 antibody (AB64829)

주요 정보

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

대체품

Primary Antibodies

보완 제품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 조건

적절한 장기 보관 조건

보관 정보

제품 프로토콜

타겟 정보

대체 명칭 보기

제품이 사용된 논문 (6)

Product promise