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AB278327

Anti-CCL1 antibody [EPR24171-79] - BSA and Azide free (Detector)

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Rabbit Recombinant Monoclonal CCL1 antibody. Carrier free. Suitable for sELISA and reacts with Human samples.

대체 명칭 보기

SCYA1, CCL1, C-C motif chemokine 1, Small-inducible cytokine A1, T lymphocyte-secreted protein I-309

1 이미지
Sandwich ELISA - Anti-CCL1 antibody [EPR24171-79] - BSA and Azide free (Detector) (AB278327)
  • sELISA

Supplier Data

Sandwich ELISA - Anti-CCL1 antibody [EPR24171-79] - BSA and Azide free (Detector) (AB278327)

Example of human CCL1 standard curve in Sample Diluent NS. Background-subtracted data values (mean +/- SD) are graphed.

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR24171-79

Isotype

IgG

Carrier free

Yes

Reacts with

Human

Applications

sELISA

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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보완 제품

Assay Kits

AB100536

Human I-309 ELISA Kit (CCL1)

Sandwich ELISA - Human I-309 ELISA Kit (CCL1) (AB100536)

  • 5
  • 1
Primary Antibodies

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Anti-FGF2 antibody [EPR20145-219]

20ul selling size|RabMAb|Recombinant

Flow Cytometry (Intracellular) - Anti-FGF2 antibody [EPR20145-219] (AB208687)

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  • 3
Primary Antibodies

AB270344

Anti-Macrophage Inflammatory Protein 3 alpha antibody [EPR22376-57] - BSA and Azide free (Capture)

RabMAb|Recombinant

Sandwich ELISA - Anti-Macrophage Inflammatory Protein 3 alpha antibody [EPR22376-57] - BSA and Azide free (Capture) (AB270344)

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  • 0
Primary Antibodies

AB242953

Anti-CD40 antibody [EPR19129-22] - BSA and Azide free (Capture)

RabMAb|Recombinant

Sandwich ELISA - Anti-CD40 antibody [EPR19129-22] - BSA and Azide free (Capture) (AB242953)

  • 0
  • 0
Primary Antibodies

AB281258

Anti-NCR1/NKp46 antibody [EPR23642-78] - BSA and Azide free (Capture)

RabMAb|Recombinant

Sandwich ELISA - Anti-NCR1/NKp46 antibody [EPR23642-78] - BSA and Azide free (Capture) (AB281258)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "sELISA-species-checked": "guaranteed", "sELISA-species-dilution-info": "", "sELISA-species-notes": "<p></p>" } } }
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제품 세부 정보

ab278327 is a BSA and Azide Free antibody supplied in an unconjugated format and it is suitable for sandwich ELISAs to quantify Human CCL1. The recommended pair for sandwich ELISA is:
Capture: ab278328, Human CCL1 Capture Antibody (unconjugated)
Detector: ab278327, Human CCL1 Detector Antibody (unconjugated)
The reference range value is 15.6 - 1000 pg/ml.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Sandwich ELISA
The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Please note that the range provided for this antibody is only an estimation based on the performance of the product using the recommended antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody in your assay.

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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

The CCL1 protein also known as I-309 protein is a cytokine that plays a significant role in the immune system. Its molecular mass is approximately 10 kDa. CCL1 is secreted by activated T cells and is found extensively in the thymus. It binds to the CCR8 receptor which suggests its involvement in immune signaling. This protein belongs to the CC chemokine family which is characterized by the presence of two adjacent cysteines near the amino terminus.
Biological function summary

CCL1 influences immune cell trafficking and activation. It attracts monocytes T lymphocytes and some types of dendritic cells to sites of inflammation. Although it is not part of a large protein complex CCL1 works with other chemokines to modulate the immune response contributing to both innate and adaptive immune mechanisms. Its expression may increase or decrease depending on the immune needs of the body.

Pathways

Studies show that CCL1 participates in the chemokine signaling pathway and the effector T-cell pathway. Within the chemokine signaling pathway CCL1 interacts with other chemokines like CCL17 and proteins involved in T-cell migration. This pathway helps coordinate the movement of immune cells to sites of inflammation or injury ensuring an effective immune response.

Research links CCL1 to conditions such as asthma and rheumatoid arthritis. In asthma CCL1 levels influence the recruitment of immune cells to the lungs contributing to inflammation and airway hyper-responsiveness. Similarly in rheumatoid arthritis its interaction with CCR8 has been associated with synovial inflammation. These diseases indicate that CCL1’s role in immune cell migration can have pathological consequences when dysregulated.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8.
See full target information CCL1
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Product promise

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