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AB231673

Anti-CD105 antibody

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(3 제품이 사용된 논문 )

Rabbit Polyclonal Endoglin antibody. Suitable for WB, IHC-P and reacts with Rat samples. Cited in 3 publications.

대체 명칭 보기

Eng

8 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD105 antibody (AB231673)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD105 antibody (AB231673)

Formalin-fixed, paraffin-embedded rat skeletal muscle tissue stained for CD105 using ab231673 at 20 μg/ml in immunohistochemical analysis. DAB staining.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD105 antibody (AB231673)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD105 antibody (AB231673)

Formalin-fixed, paraffin-embedded rat lung tissue stained for CD105 using ab231673 at 20 μg/ml in immunohistochemical analysis. DAB staining.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD105 antibody (AB231673)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD105 antibody (AB231673)

Formalin-fixed, paraffin-embedded rat stomach tissue stained for CD105 using ab231673 at 20 μg/ml in immunohistochemical analysis. DAB staining.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD105 antibody (AB231673)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD105 antibody (AB231673)

Formalin-fixed, paraffin-embedded rat kidney tissue stained for CD105 using ab231673 at 20 μg/ml in immunohistochemical analysis. DAB staining.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD105 antibody (AB231673)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD105 antibody (AB231673)

Formalin-fixed, paraffin-embedded rat spinal cord tissue stained for CD105 using ab231673 at 20 μg/ml in immunohistochemical analysis. DAB staining.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD105 antibody (AB231673)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD105 antibody (AB231673)

Formalin-fixed, paraffin-embedded rat colon tissue stained for CD105 using ab231673 at 20 μg/ml in immunohistochemical analysis. DAB staining.

Western blot - Anti-CD105 antibody (AB231673)
  • WB

Supplier Data

Western blot - Anti-CD105 antibody (AB231673)

All lanes:

Western blot - Anti-CD105 antibody (ab231673) at 1 µg/mL

Lane 1:

Rat serum

Lane 2:

Rat kidney lysate

Secondary

All lanes:

HRP-Linked Guinea pig anti-Rabbit at 1/2000 dilution

Predicted band size: 70 kDa

false

Western blot - Anti-CD105 antibody (AB231673)
  • WB

Supplier Data

Western blot - Anti-CD105 antibody (AB231673)

All lanes:

Western blot - Anti-CD105 antibody (ab231673) at 1 µg/mL

All lanes:

Recombinant rat CD105 protein

Secondary

All lanes:

HRP-Linked Guinea pig anti-Rabbit at 1/2000 dilution

Predicted band size: 70 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Rat

Applications

IHC-P, WB

applications

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대체품

Primary Antibodies

AB252345

Anti-CD105 antibody [EPR19911-220]

20ul selling size|BOND RX™ Validated|RabMAb|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD105 antibody [EPR19911-220] (AB252345)

  • 5
  • 2
Primary Antibodies

AB11414

Anti-CD105 antibody [SN6]

Flow Cytometry - Anti-CD105 antibody [SN6] (AB11414)

  • 5
  • 6
Primary Antibodies

AB206419

Anti-CD105 antibody [EPR19911]

RabMAb|Recombinant|KO Validated|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD105 antibody [EPR19911] (AB206419)

  • 0
  • 0
Primary Antibodies

AB170943

Anti-CD105 antibody [EPR10145-10]

20ul selling size|RabMAb|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD105 antibody [EPR10145-10] (AB170943)

  • 0
  • 0
Primary Antibodies

AB169545

Anti-CD105 antibody [EPR10145-12]

20ul selling size|RabMAb|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD105 antibody [EPR10145-12] (AB169545)

  • 4
  • 3
Primary Antibodies

AB219362

Anti-CD105 antibody [EPR10145-12] - Low endotoxin, Azide free

RabMAb|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD105 antibody [EPR10145-12] - Low endotoxin, Azide free (AB219362)

  • 5
  • 1
Primary Antibodies

AB221675

Anti-CD105 antibody [EPR21846]

RabMAb|Recombinant|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD105 antibody [EPR21846] (AB221675)

  • 0
  • 0
Primary Antibodies

AB231832

Anti-CD105 antibody [EPR21846] - BSA and Azide free

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD105 antibody [EPR21846] - BSA and Azide free (AB231832)

  • 0
  • 0

보완 제품

Primary Antibodies

AB283654

Anti-CD68 antibody [EPR23917-164]

BOND RX™ Validated|RabMAb|Recombinant|KO Validated|Lab Essentials|20ul selling size|Advanced Validation

Flow Cytometry - Anti-CD68 antibody [EPR23917-164] (AB283654)

  • 5
  • 1
Primary Antibodies

AB182422

Anti-CD163 antibody [EPR19518]

BOND RX™ Validated|20ul selling size|RabMAb|Advanced Validation|Recombinant

Flow Cytometry - Anti-CD163 antibody [EPR19518] (AB182422)

  • 5
  • 17
Primary Antibodies

AB31630

Anti-CD68 antibody [ED1]

Lab Essentials

Flow Cytometry (Intracellular) - Anti-CD68 antibody [ED1] (AB31630)

  • 5
  • 21
Primary Antibodies

AB252921

Anti-CD206 antibody [EPR22489-7]

RabMAb|Recombinant|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD206 antibody [EPR22489-7] (AB252921)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Rat": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.5-2 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5-20 µg/mL", "IHCP-species-notes": "<p></p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
Purification 관련 사항
Antigen-specific affinity chromatography followed by Protein A affinity chromatography.
보관 버퍼
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

CD105 also known as endoglin or the CD105 marker is a transmembrane glycoprotein with a molecular weight of approximately 180 kDa. It is a component of the TGF-beta receptor complex and exists in endothelial cells where it is abundantly expressed. Expression of CD105 is higher in proliferating cells particularly in the vasculature. You can also find it in tissues involved in the formation and remodeling of blood vessels such as during angiogenesis.
Biological function summary

Endoglin functions in the regulation of angiogenesis and vascular remodeling. It plays a significant role in mediating cellular responses to TGF-beta signaling influencing endothelial cell proliferation and migration. While not part of a larger structural complex endoglin interacts with receptors and signaling molecules important for vascular development and repair processes. This involvement aids in maintaining endothelial integrity and function under various physiological conditions.

Pathways

CD105 participates in the TGF-beta signaling and angiogenesis pathways. In these pathways it acts in conjunction with other proteins like TGF-beta receptors which play roles in cell differentiation proliferation and apoptosis. The interaction between CD105 and TGF-beta signaling regulates numerous cellular mechanisms impacting angiogenesis and cellular responses to environmental changes.

CD105 has links to hereditary hemorrhagic telangiectasia (HHT) and certain cancers. In HHT mutations in the endoglin gene alter vascular structure leading to the formation of abnormal blood vessels. Oncologically overexpression of CD105 is present in tumor angiogenesis aiding in the progression of certain cancers. Other proteins like VEGF and TGF-beta closely interact with endoglin influencing disease progression and presenting potential targets for therapeutic intervention.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

See full target information Endoglin
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제품이 사용된 논문 (3)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Bone & joint research 12:615-623 PubMed37783468

2023

Regeneration of injured articular cartilage using the recombinant human amelogenin protein.

Applications

Unspecified application

Species

Unspecified reactive species

Omer Helwa-Shalom,Faris Saba,Elad Spitzer,Salem Hanhan,Koby Goren,Shany I Markowitz,Dekel Shilo,Nissim Khaimov,Yechiel N Gellman,Dan Deutsch,Anat Blumenfeld,Hani Nevo,Amir Haze

Journal of veterinary research 67:307-314 PubMed38143820

2023

Functional and morphological maturation of the full-sized and mini-pig corpus luteum by programmed cell death mechanism.

Applications

Unspecified application

Species

Unspecified reactive species

Ji-Hye Lee,Sang-Hwan Kim

Biomaterials research 24:17 PubMed33014414

2020

In vivo bone regeneration assessment of offset and gradient melt electrowritten (MEW) PCL scaffolds.

Applications

Unspecified application

Species

Unspecified reactive species

Naghmeh Abbasi,Ryan S B Lee,Saso Ivanovski,Robert M Love,Stephen Hamlet
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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