Anti-CD20 antibody [MEM-97]
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(3 제품이 사용된 논문 )
- Flow Cyt
Unknown
Flow Cytometry - Anti-CD20 antibody [MEM-97] (AB8237)
Double Immunostaining of CD20 and CD79a in human, canine and porcine B lymphocytes using ab8237 and ab76908 by Flow Cytometery.
- Flow Cyt
Supplier Data
Flow Cytometry - Anti-CD20 antibody [MEM-97] (AB8237)
Flow cytometry surface staining pattern of human peripheral whole blood stained using ab8237 (concentration in sample 1.6 μg/ml) GAM APC.
- Flow Cyt
Supplier Data
Flow Cytometry - Anti-CD20 antibody [MEM-97] (AB8237)
Separation of human CD20 positive lymphocytes (red-filled) from neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using ab8237 (concentration in sample 1.6 μg/ml) GAM APC.
- IP
Unknown
Immunoprecipitation - Anti-CD20 antibody [MEM-97] (AB8237)
Immunoprecipitation of human CD20 from the whole cell lysate of RAJI human Burkitt lymphoma cell line. Western blot was immunostained with anti-CD20 rabbit polyclonal antibody. Lane 1 : original lysate of RAJI cells Lane 2 : immunoprecipitate by Isotypic mouse IgG1 control Lane 3 : original lysate of RAJI cells Lane 4 : immunoprecipitate by anti-CD20 (MEM-97, ab 8237)
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Immunoprecipitation - Anti-CD20 antibody [MEM-97] (ab8237)
Predicted band size: 33 kDa
false
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Purification 테크닉
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This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
CD20 contributes significantly to calcium ion transport which is essential for the activation process of B-cells. Although CD20 does not belong to a larger protein complex its role centers around forming a calcium channel that allows a sustained influx of calcium into the B-cells. This influx is important for the signaling pathways that govern B-cell activation proliferation and differentiation impacting the immune response efficacy.
Pathways
CD20 is closely involved in the B-cell receptor (BCR) signaling pathway and the Fc gamma R-mediated phagocytosis pathway. These pathways play vital roles in adaptive immunity and immune response modulation. CD20's interaction with proteins like PI3K during BCR signaling enhances receptor-mediated cellular signals subsequently influencing downstream effectors involved in cell growth and survival of B-cells.
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제품이 사용된 논문 (3)
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Journal of cellular and molecular medicine 21:254-264 PubMed27860183
2016
Applications
Flow Cyt
Species
Human
Oncotarget 2:59-68 PubMed21378416
2011
Applications
Unspecified application
Species
Mouse
Journal of immunology (Baltimore, Md. : 1950) 157:2939-46 PubMed8816400
1996
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Unspecified application
Species
Unspecified reactive species
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