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AB281154

Anti-Chromogranin C/SGII antibody [EPR23876-49] - BSA and Azide free (Capture)

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Rabbit Recombinant Monoclonal Chromogranin C/SGII antibody. Carrier free. Suitable for sELISA and reacts with Human samples.
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Sandwich ELISA - Anti-Chromogranin C/SGII antibody [EPR23876-49] - BSA and Azide free (Capture) (AB281154)
  • sELISA

Supplier Data

Sandwich ELISA - Anti-Chromogranin C/SGII antibody [EPR23876-49] - BSA and Azide free (Capture) (AB281154)

Example of human Chromogranin C/SGII standard curve in 1X Cell Extraction Buffer PTR. Background-subtracted data values (mean +/- SD) are graphed.

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR23876-49

Isotype

IgG

Carrier free

Yes

Reacts with

Human

Applications

sELISA

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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보완 제품

Assay Kits

AB304940

Human Chromogranin C/SGII ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Human Chromogranin C/SGII ELISA Kit (AB304940)

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Sample Prep & Detection Kits

AB201804

DyLight® 680 Conjugation Kit (Fast) - Lightning-Link®

Schematic Diagram - DyLight® 680 Conjugation Kit (Fast) - Lightning-Link® (AB201804)

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Sample Prep & Detection Kits

AB188290

Gold-Maleimide Conjugation Kit (40nm, 20 OD)

Lateral flow assay - Gold-Maleimide Conjugation Kit (40nm, 20 OD) (AB188290)

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Primary Antibodies

AB281094

Anti-Wnt16 antibody [EPR22889-129] - BSA and Azide free (Detector)

RabMAb|Recombinant

Sandwich ELISA - Anti-Wnt16 antibody [EPR22889-129] - BSA and Azide free (Detector) (AB281094)

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Primary Antibodies

AB270332

Anti-ILT-4 antibody [EPR22081-33] - BSA and Azide free (Capture)

RabMAb|Recombinant

Sandwich ELISA - Anti-ILT-4 antibody [EPR22081-33] - BSA and Azide free (Capture) (AB270332)

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Primary Antibodies

AB318216

Anti-Munc18-1 antibody [EPR27956-33] - BSA and Azide free (Detector)

Recombinant|RabMAb

Sandwich ELISA - Anti-Munc18-1 antibody [EPR27956-33] - BSA and Azide free (Detector) (AB318216)

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Primary Antibodies

AB275229

Anti-VILIP1 antibody [EPR23794-168] - BSA and Azide free (Detector)

RabMAb|Recombinant

Sandwich ELISA - Anti-VILIP1 antibody [EPR23794-168] - BSA and Azide free (Detector) (AB275229)

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  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "sELISA-species-checked": "guaranteed", "sELISA-species-dilution-info": "", "sELISA-species-notes": "<p></p>" } } }
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제품 세부 정보

ab281154 is a BSA and Azide Free antibody supplied in an unconjugated format and it is suitable for sandwich ELISAs to quantify Human SCG2. The recommended pair for sandwich ELISA is:
Capture: ab281154, Human SCG2 Capture Antibody (unconjugated)
Detector: ab281004, Human SCG2 Detector Antibody (unconjugated)
The reference range value is 313 - 20000 pg/mL.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Sandwich ELISA
The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Please note that the range provided for this antibody is only an estimation based on the performance of the product using the recommended antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody in your assay.

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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Chromogranin C also known as secretogranin II (SGII) is a member of the granin family and weighs approximately 68 kDa. This protein is mainly located within the dense core secretory granules of endocrine and neuronal cells. It plays a mechanical role in the storage and release of peptide hormones and neurotransmitters. Chromogranin C is found in various regions of the brain adrenal medulla and in the pituitary gland reflecting its involvement in the neuroendocrine system.
Biological function summary

This protein functions in the regulation of peptide hormone secretion and is part of a complex with other granin proteins such as Chromogranin A. It modulates the granule's environment by affecting the pH and ionic composition which influences the storage and release of hormones and neurotransmitters. Chromogranin C participates in the production of biologically active peptides after proteolytic processing playing roles in the modulation of endocrine and neuronal activities.

Pathways

Chromogranin C connects to the neuroendocrine signaling pathways and regulated secretory pathway. Within these pathways it interacts with other proteins such as the prohormone convertases and furin which handle peptide precursors' cleavage into active hormones and neurotransmitters. This procession is important for maintaining cellular communication and response mechanisms linking Chromogranin C to cellular signaling and biochemical processes that control physiological homeostasis and stress responses.

Chromogranin C correlates with neurodegenerative diseases like Alzheimer's disease and psychiatric disorders such as depression. These connections arise through its relationship with amyloid precursor protein in Alzheimer's and alterations in serotonergic systems in depression. The expression levels and processing of Chromogranin C may serve as a biomarker for these diseases highlighting its potential role in the pathogenesis and progression of neuro-psychiatric conditions.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Neuroendocrine protein of the granin family that regulates the biogenesis of secretory granules.
See full target information SCG2

대체 명칭 보기

CHGC, SCG2, Secretogranin-2, Chromogranin-C, Secretogranin II, SgII
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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