AB239078

Anti-CLEC4C antibody [EPR21985]

20ul selling size
RabMAb
Recombinant
각 태그의 뜻

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(4 제품이 사용된 논문 )

Rabbit Recombinant Monoclonal CLEC4C antibody. Suitable for Flow Cyt, IHC-P and reacts with Human samples. Cited in 4 publications.

대체 명칭 보기

CD303, BDCA2, CLECSF11, CLECSF7, DLEC, HECL, UNQ9361/PRO34150, CLEC4C, C-type lectin domain family 4 member C, Blood dendritic cell antigen 2, C-type lectin superfamily member 7, Dendritic lectin, BDCA-2

3 이미지

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CLEC4C antibody [EPR21985] (AB239078)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CLEC4C antibody [EPR21985] (AB239078)

Immunohistochemical analysis of paraffin-embedded human cardiac muscle tissue labeling CLEC4C with ab239078 at 1/1000 dilution, followed by Goat Anti-Rabbit IgG H&L (HRP) Ready to use.

Negative control : Negative staining in human cardiac muscle (PMID : 11748283).

Counter stained with hematoxylin.

Flow Cytometry - Anti-CLEC4C antibody [EPR21985] (AB239078)

Flow Cyt

Supplier Data

Flow Cytometry - Anti-CLEC4C antibody [EPR21985] (AB239078)

Flow cytometric analysis of primary human peripheral blood mononuclear cell (PBMC) labeling CLEC4C with ab239078 at 1/60 dilution (right panel) compared with a Rabbit IgG, monoclonal [EPR25A] - Isotype Control (ab172730) (left panel). Goat Anti-Rabbit IgG Fc (Dylight^® 488) (ab98462) at 1/2000 dilution was used as the secondary antibody.

Gated on viable cells.

Note : CLEC4C and CD303 are alternative names for the same target.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CLEC4C antibody [EPR21985] (AB239078)

Immunohistochemical analysis of paraffin-embedded human tonsil tissue labeling CLEC4C with ab239078 at 1/1000 dilution, followed by Goat Anti-Rabbit IgG H&L (HRP) Ready to use. Membranous staining in plasmacytoid dendritic cells (PDCs) of human tonsil (PMID : 23847189, PMID : 11748283). Counter stained with hematoxylin.

Secondary antibody only control : Used PBS instead of primary antibody, secondary antibody is Goat Anti-Rabbit IgG H&L (HRP) Ready to use.

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR21985

Isotype

IgG

Carrier free

Reacts with

Human

Applications

IHC-P, Flow Cyt

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "FlowCyt" : {"fullname" : "Flow Cytometry", "shortname":"Flow Cyt"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "FlowCyt-species-checked": "testedAndGuaranteed", "FlowCyt-species-dilution-info": "1/60", "FlowCyt-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/1000", "IHCP-species-notes": "" }, "Mouse": { "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "1/1000", "IHCP-species-notes": "" }, "Rat": { "FlowCyt-species-checked": "notRecommended", "FlowCyt-species-dilution-info": "", "FlowCyt-species-notes": "", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "1/1000", "IHCP-species-notes": "" } } }

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제품 세부 정보

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Protein A

보관 버퍼

Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

배송 시 보관 조건

Conditional Ambient

적절한 단기 보관 기간

1-2 weeks

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells (PubMed : 11748283, PubMed : 21880719, PubMed : 25995448). Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man (PubMed : 21880719, PubMed : 25995448). Binds to serum IgG (PubMed : 25995448). Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells (PubMed : 11748283). May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells (PubMed : 11748283, PubMed : 21880719). May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium (PubMed : 11748283).

See full target information CLEC4C

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제품이 사용된 논문 (4)

Recent publications for all applications. Explore the 전체 목록 and refine your search

The Journal of experimental medicine 222: PubMed40227192

2025

Enhanced TLR7-dependent production of type I interferon by pDCs underlies pandemic chilblains.

Applications

Unspecified application

Species

Unspecified reactive species

Fanny Saidoune,Danyel Lee,Jeremy Di Domizio,Corentin Le Floc'h,Raphael Jenelten,Jérémie Le Pen,Vincent Bondet,Ana Joncic,Marie-Anne Morren,Vivien Béziat,Shen-Ying Zhang,Emmanuelle Jouanguy,Darragh Duffy,Charles M Rice,Curdin Conrad,Jacques Fellay,Jean-Laurent Casanova,Michel Gilliet,Ahmad Yatim

Nature communications 15:8690 PubMed39375367

2024

Single-cell RNA sequencing reveals the pro-inflammatory roles of liver-resident Th1-like cells in primary biliary cholangitis.

Applications

Unspecified application

Species

Unspecified reactive species

Ciliang Jin,Penglei Jiang,Zhaoru Zhang,Yingli Han,Xue Wen,Lin Zheng,Wei Kuang,Jiangshan Lian,Guodong Yu,Xinyue Qian,Yue Ren,Miaomiao Lu,Lingling Xu,Weixin Chen,Jiyang Chen,Yuwei Zhou,Jinxia Xin,Ben Wang,Xi Jin,Pengxu Qian,Yida Yang

MedComm 5:e561 PubMed38721005

2024

PA28γ induces dendritic cell maturation and activates T-cell immune responses in oral lichen planus.

Applications

Unspecified application

Species

Unspecified reactive species

Yimei Wang,Qiyue Zhang,Xiaoting Deng,Ying Wang,Xin Tian,Shiyu Zhang,Yingqiang Shen,Xikun Zhou,Xin Zeng,Qianming Chen,Lu Jiang,Jing Li

Genome medicine 15:14 PubMed36869384

2023

Tumor microenvironment remodeling after neoadjuvant immunotherapy in non-small cell lung cancer revealed by single-cell RNA sequencing.

Applications

Unspecified application

Species

Unspecified reactive species

Junjie Hu,Lele Zhang,Haoran Xia,Yilv Yan,Xinsheng Zhu,Fenghuan Sun,Liangdong Sun,Shuangyi Li,Dianke Li,Jin Wang,Ya Han,Jing Zhang,Dongliang Bian,Huansha Yu,Yan Chen,Pengyu Fan,Qiang Ma,Gening Jiang,Chenfei Wang,Peng Zhang

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-CLEC4C antibody [EPR21985]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CLEC4C antibody [EPR21985] (AB239078)

Flow Cytometry - Anti-CLEC4C antibody [EPR21985] (AB239078)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CLEC4C antibody [EPR21985] (AB239078)

관련 conjugated 항체와 다양한 조성의 항체 (9)

주요 정보

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

보완 제품

Assay Kits

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

제품 세부 정보

특성 및 보관 정보

제형

Purification 테크닉

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 기간

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

제품 프로토콜

타겟 정보

제품이 사용된 논문 (4)

Product promise