AB13712

Anti-CLLD8/SETDB2 antibody

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(3 제품이 사용된 논문 )

Goat Polyclonal CLLD8/SETDB2 antibody. Suitable for WB and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Synthetic Peptide within Human SETDB2 aa 1-50.

대체 명칭 보기

C13orf4, CLLD8, KMT1F, SETDB2, Histone-lysine N-methyltransferase SETDB2, Chronic lymphocytic leukemia deletion region gene 8 protein, Lysine N-methyltransferase 1F, SET domain bifurcated 2

1 이미지

Supplier Data

Western blot - Anti-CLLD8/SETDB2 antibody (AB13712)

Detected by chemiluminescence.

RIPA buffer.

All lanes:

Western blot - Anti-CLLD8/SETDB2 antibody (ab13712) at 0.3 µg/mL

All lanes:

HeLa (Human epithelial cell line from cervix adenocarcinoma) nuclear lysate at 35 µg

Predicted band size: 82 kDa

false

주요 정보

Host species

Goat

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

applications

Immunogen

Synthetic Peptide within Human SETDB2 aa 1-50. The exact immunogen used to generate this antibody is proprietary information.

Q96T68

Specificity

This antibody has been shown to detect SETDB2 in overexpression cell extracts.

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "<p>1 hour primary incubation is recommended for this product.</p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Dog": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Pig": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Immunogen

Purification 관련 사항

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

보관 버퍼

pH: 7.3 Preservative: 0.02% Sodium azide Constituents: 99% Tris buffered saline, 0.5% BSA

배송 시 보관 조건

Blue Ice

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Histone methyltransferase involved in left-right axis specification in early development and mitosis. Specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3K9me3 is a specific tag for epigenetic transcriptional repression that recruits HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Contributes to H3K9me3 in both the interspersed repetitive elements and centromere-associated repeats. Plays a role in chromosome condensation and segregation during mitosis.

See full target information SETDB2

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제품이 사용된 논문 (3)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Oncology reports 45: PubMed33846793

2021

CREB stimulates GPX4 transcription to inhibit ferroptosis in lung adenocarcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Zhixian Wang,Xiao Zhang,Xiaoting Tian,Yueyue Yang,Lifang Ma,Jiayi Wang,Yongchun Yu

Cancer management and research 12:783-792 PubMed32099474

2020

Oncogenic Roles Of A Histone Methyltransferase SETDB2 In AML1-ETO Positive AML.

Applications

Unspecified application

Species

Unspecified reactive species

Guangfu Mu,Fangping Chen

Cancer cell 35:677-691.e10 PubMed30991027

2019

Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia.

Applications

Unspecified application

Species

Unspecified reactive species

Yue Huang,Rui Su,Yue Sheng,Lei Dong,Ze Dong,Hongjiao Xu,Tengfeng Ni,Zijie Scott Zhang,Tao Zhang,Chenying Li,Li Han,Zhenyun Zhu,Fulin Lian,Jiangbo Wei,Qiangqiang Deng,Yungui Wang,Mark Wunderlich,Zhiwei Gao,Guoyu Pan,Dafang Zhong,Hu Zhou,Naixia Zhang,Jianhua Gan,Hualiang Jiang,James C Mulloy,Zhijian Qian,Jianjun Chen,Cai-Guang Yang

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-CLLD8/SETDB2 antibody

Western blot - Anti-CLLD8/SETDB2 antibody (AB13712)

주요 정보

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

Specificity

대체품

Primary Antibodies

보완 제품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

Purification 관련 사항

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

제품 프로토콜

타겟 정보

제품이 사용된 논문 (3)

Product promise