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AB214937

Anti-CNOT4 antibody

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(3 제품이 사용된 논문 )

Rabbit Polyclonal CNOT4 antibody. Suitable for IHC-P, WB and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Fragment Protein within Human CNOT4 aa 300 to C-terminus.

대체 명칭 보기

NOT4, CNOT4, CCR4-NOT transcription complex subunit 4, CCR4-associated factor 4, E3 ubiquitin-protein ligase CNOT4, Potential transcriptional repressor NOT4Hp, RING-type E3 ubiquitin transferase CNOT4

2 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CNOT4 antibody (AB214937)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CNOT4 antibody (AB214937)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human testis tissue labeling CNOT4 with ab214937 at 1/50 dilution.

Western blot - Anti-CNOT4 antibody (AB214937)
  • WB

Unknown

Western blot - Anti-CNOT4 antibody (AB214937)

All lanes:

Western blot - Anti-CNOT4 antibody (ab214937) at 1/50 dilution

All lanes:

Human cell line SiHa

Predicted band size: 63 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human CNOT4 aa 300 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

O95628

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/200", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.04-0.4 µg/mL", "WB-species-notes": "<p></p>" } } }

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

타겟 정보

Has E3 ubiquitin ligase activity, promoting ubiquitination and degradation of target proteins (PubMed : 11823428, PubMed : 22159038, PubMed : 26575292). Involved in activation of the JAK/STAT pathway (PubMed : 11823428, PubMed : 22159038). Catalyzes ubiquitination of methylated RBM15 (PubMed : 26575292). Plays a role in quality control of translation of mitochondrial outer membrane-localized mRNA (PubMed : 29861391). As part of the PINK1-regulated signaling, upon mitochondria damage, ubiquitinates ABCE1 and thereby recruits autophagy receptors to the mitochondrial outer membrane to initiate mitophagy (PubMed : 29861391).
See full target information CNOT4

제품이 사용된 논문 (3)

Recent publications for all applications. Explore the 전체 목록 and refine your search

RNA (New York, N.Y.) 30:1572-1585 PubMed39293933

2024

Translation elongation inhibitors stabilize select short-lived transcripts.

Applications

Unspecified application

Species

Unspecified reactive species

Nicolle A Rosa-Mercado,Allen R Buskirk,Rachel Green

Molecular cell 83:2290-2302.e13 PubMed37295431

2023

Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation.

Applications

Unspecified application

Species

Unspecified reactive species

Markus Höpfler,Eva Absmeier,Sew-Yeu Peak-Chew,Evangelia Vartholomaiou,Lori A Passmore,Ivana Gasic,Ramanujan S Hegde

Annals of translational medicine 7:723 PubMed32042739

2020

Epigenetic hypomethylation and upregulation of GD3s in triple negative breast cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Wan Li,Xiangjin Zheng,Liwen Ren,Weiqi Fu,Jinyi Liu,Jun Xv,Shiwei Liu,Jinhua Wang,Guanhua Du
제품이 사용된 논문 모두 보기

Product promise

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