AB115169

Anti-COMMD4 antibody

Be the first to review this product! 리뷰 제출

(5 제품이 사용된 논문 )

Rabbit Polyclonal COMMD4 antibody. Suitable for WB and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Synthetic Peptide within Human COMMD4 aa 100-200.

대체 명칭 보기

COMM domain-containing protein 4, COMMD4

1 이미지

Unknown

Western blot - Anti-COMMD4 antibody (AB115169)

All lanes:

Western blot - Anti-COMMD4 antibody (ab115169) at 0.4 µg/mL

Lane 1:

HeLa cell lysate at 50 µg

Lane 2:

HeLa cell lysate at 15 µg

Lane 3:

HeLa cell lysate at 5 µg

Lane 4:

293T cell lysate at 50 µg

Predicted band size: 22 kDa

false

Exposure time: 10s

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

applications

Immunogen

Synthetic Peptide within Human COMMD4 aa 100-200. The exact immunogen used to generate this antibody is proprietary information.

Q9H0A8

style

left-column

style

left-column

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000 - 1/10000", "WB-species-notes": "<p></p>" }, "Bat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Chimpanzee": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Elephant": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Gorilla": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Horse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Orangutan": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rhesus monkey": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }

style

left-column

style

left-column

특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Immunogen

보관 버퍼

pH: 7 - 8 Preservative: 0.09% Sodium azide Constituents: 99% Tris citrate/phosphate

배송 시 보관 조건

Blue Ice

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

+4°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

style

left-column

style

left-column

style

left-column

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

style

left-column

타겟 정보

Scaffold protein in the commander complex that is essential for endosomal recycling of transmembrane cargos; the commander complex is composed of the CCC subcomplex and the retriever subcomplex (PubMed : 37172566, PubMed : 38459129). May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed : 21778237). Down-regulates activation of NF-kappa-B (PubMed : 23637203).

See full target information COMMD4

style

left-column

제품이 사용된 논문 (5)

Recent publications for all applications. Explore the 전체 목록 and refine your search

British journal of cancer 129:2014-2024 PubMed37914802

2023

Targeting the COMMD4-H2B protein complex in lung cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Ming Tang,Joshua T Burgess,Mark Fisher,Didier Boucher,Emma Bolderson,Neha S Gandhi,Kenneth J O'Byrne,Derek J Richard,Amila Suraweera

Cell 186:2219-2237.e29 PubMed37172566

2023

Structure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome.

Applications

Unspecified application

Species

Unspecified reactive species

Michael D Healy,Kerrie E McNally,Rebeka Butkovič,Molly Chilton,Kohji Kato,Joanna Sacharz,Calum McConville,Edmund R R Moody,Shrestha Shaw,Vicente J Planelles-Herrero,Sathish K N Yadav,Jennifer Ross,Ufuk Borucu,Catherine S Palmer,Kai-En Chen,Tristan I Croll,Ryan J Hall,Nikeisha J Caruana,Rajesh Ghai,Thi H D Nguyen,Kate J Heesom,Shinji Saitoh,Imre Berger,Christiane Schaffitzel,Tom A Williams,David A Stroud,Emmanuel Derivery,Brett M Collins,Peter J Cullen

Communications biology 4:484 PubMed33875784

2021

COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks.

Applications

Unspecified application

Species

Unspecified reactive species

Amila Suraweera,Neha S Gandhi,Sam Beard,Joshua T Burgess,Laura V Croft,Emma Bolderson,Ali Naqi,Nicholas W Ashton,Mark N Adams,Kienan I Savage,Shu-Dong Zhang,Kenneth J O'Byrne,Derek J Richard

British journal of cancer 123:591-603 PubMed32439936

2020

Defining COMMD4 as an anti-cancer therapeutic target and prognostic factor in non-small cell lung cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Amila Suraweera,Alex Duff,Mark N Adams,Christian Jekimovs,Pascal H G Duijf,Cheng Liu,Matthew McTaggart,Sam Beard,Kenneth J O' Byrne,Derek J Richard

Physiological reports 7:e14100 PubMed31090216

2019

Signaling responses to high and moderate load strength exercise in trained muscle.

Applications

Unspecified application

Species

Unspecified reactive species

Evgeny A Lysenko,Daniil V Popov,Tatiana F Vepkhvadze,Anna P Sharova,Olga L Vinogradova

제품이 사용된 논문 모두 보기

style

left-column

style

left-column

style

right-column

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-COMMD4 antibody

Western blot - Anti-COMMD4 antibody (AB115169)

주요 정보

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

보완 제품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

제품 프로토콜

타겟 정보

제품이 사용된 논문 (5)

Product promise