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AB169543

Anti-CR1L antibody [EPR9604(B)]

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Rabbit Recombinant Monoclonal Crry antibody. Suitable for WB, Flow Cyt (Intra) and reacts with Human samples. Cited in 1 publication.

대체 명칭 보기

Complement component receptor 1-like protein, Complement C4b-binding protein CR-1-like protein, CR1L

2 이미지
Flow Cytometry (Intracellular) - Anti-CR1L antibody [EPR9604(B)] (AB169543)
  • Flow Cyt (Intra)

Unknown

Flow Cytometry (Intracellular) - Anti-CR1L antibody [EPR9604(B)] (AB169543)

Intracellular flow cytometric analysis of permeabilized HepG2 cells labeling CR1L with ab169543 at 1/100 dilution (red) compared to a rabbit IgG (negative) (green).

Western blot - Anti-CR1L antibody [EPR9604(B)] (AB169543)
  • WB

Unknown

Western blot - Anti-CR1L antibody [EPR9604(B)] (AB169543)

All lanes:

Western blot - Anti-CR1L antibody [EPR9604(B)] (ab169543) at 1/1000 dilution

Lane 1:

HepG2 cell lysate at 10 µg

Lane 2:

Ramos cell lysate at 10 µg

Lane 3:

K562 cell lysate at 10 µg

Lane 4:

MOLT4 cell lysate at 10 µg

Secondary

All lanes:

Goat anti-rabbit HRP at 1/2000 dilution

Predicted band size: 63 kDa

false

관련 conjugated 항체와 다양한 조성의 항체 (1)

  • Carrier free

    Anti-CR1L antibody [EPR9604(B)] - BSA and Azide free

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR9604(B)

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

Flow Cyt (Intra), WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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보완 제품

Proteins & Peptides

AB238362

Recombinant Mouse CR1L protein (His tag)

SDS-PAGE - Recombinant Mouse CR1L protein (His tag) (AB238362)

  • 0
  • 0
Primary Antibodies

AB184308

Anti-CD11b antibody [EPR19387]

RabMAb|Recombinant|Lab Essentials|20ul selling size

Immunocytochemistry/ Immunofluorescence - Anti-CD11b antibody [EPR19387] (AB184308)

  • 4
  • 1
Primary Antibodies

AB201460

Anti-HNF-4-alpha antibody [EPR16885-99]

20ul selling size|RabMAb|Advanced Validation|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-HNF-4-alpha antibody [EPR16885-99] (AB201460)

  • 4
  • 2
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "FlowCytIntra" : {"fullname" : "Flow Cytometry (Intracellular)", "shortname":"Flow Cyt (Intra)"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "<p></p>", "FlowCytIntra-species-checked": "testedAndGuaranteed", "FlowCytIntra-species-dilution-info": "1/100 - 1/500", "FlowCytIntra-species-notes": "<p><a href='/ko/products/primary-antibodies/rabbit-igg-monoclonal-epr25a-isotype-control-ab172730'>ab172730</a> - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.</p>", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" } } }
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제품 세부 정보

Species reactivity
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species.
Please contact us for more information.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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특성 및 보관 정보

제형
Liquid
보관 버퍼
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
배송 시 보관 조건
Conditional Ambient
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

CR1L also known as CR1-like or C3b/C4b receptor 1-like is a protein encoded by the CR1L gene. This protein functions mechanically as a receptor that interacts specifically with complement components C3b and C4b playing roles in immune complex processing. The molecular mass of CR1L is approximately 130 kDa. Expression of CR1L occurs mostly in the liver certain cells of the hematopoietic lineage and in platelets.
Biological function summary

CR1L acts as part of the immune system by binding to complement fragments on opsonized pathogens which facilitates their clearance. It forms part of a receptor complex that clears immune complexes and helps in modulating the complement cascade. CR1L's involvement in complement regulation highlights its contribution to preventing excessive inflammation and protecting host tissues during immune defense.

Pathways

CR1L plays a significant role in the complement activation pathway specifically in classical and alternative pathways. These pathways involve proteins such as factor H and factor I which work alongside CR1L to ensure proper regulation of complement activity. By binding C3b and C4b CR1L helps in the breakdown of these components and assists in maintaining homeostasis by moderating complement activity.

CR1L associates with autoimmune conditions such as systemic lupus erythematosus and atypical hemolytic uremic syndrome. These disorders often involve dysregulation of complement activity. CR1L interacts with other complement regulatory proteins such as complement receptor 2 (CR2) in these contexts where imbalances in complement system function can lead to tissue damage and inflammation.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

See full target information CR1L
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

International journal of medical sciences 22:3477-3489 PubMed40860777

2025

NDUFS1 upregulates ENaCα by NAD+ to promote alveolar fluid clearance in acute lung injury.

Applications

Unspecified application

Species

Unspecified reactive species

Mengmeng Wang,Mengting Chen,Jianping Zhu,Yu Zhang,Jian Lu,Zhiying Yue,Zhengfeng Yang,Ruilan Wang
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

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