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AB157219

Anti-CTRL antibody [EPR11490(B)]

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Rabbit Recombinant Monoclonal CTRL antibody. Suitable for WB and reacts with Mouse, Rat, Human samples. Cited in 1 publication.

대체 명칭 보기

CTRL1, CTRL, Chymotrypsin-like protease CTRL-1

1 이미지
Western blot - Anti-CTRL antibody [EPR11490(B)] (AB157219)
  • WB

Unknown

Western blot - Anti-CTRL antibody [EPR11490(B)] (AB157219)

All lanes:

Western blot - Anti-CTRL antibody [EPR11490(B)] (ab157219) at 1/10000 dilution

Lane 1:

Mouse pancreas lysate at 10 µg

Lane 2:

Rat pancreas lysate at 10 µg

Lane 3:

Human fetal pancreas lysate at 10 µg

Predicted band size: 28 kDa

false

관련 conjugated 항체와 다양한 조성의 항체 (1)

  • Carrier free

    Anti-CTRL antibody [EPR11490(B)] - BSA and Azide free

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR11490(B)

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Rat, Human

Applications

WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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보완 제품

Primary Antibodies

AB174286

Anti-MYO19 antibody [EPR12551-13]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-MYO19 antibody [EPR12551-13] (AB174286)

  • 5
  • 1
Primary Antibodies

AB174302

Anti-ETHE1 antibody [EPR11697]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ETHE1 antibody [EPR11697] (AB174302)

  • 0
  • 0
Primary Antibodies

AB157188

Anti-STK25 antibody [EPR10306]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-STK25 antibody [EPR10306] (AB157188)

  • 2
  • 1
Primary Antibodies

AB154846

Anti-GNAZ antibody [EPR8654]

RabMAb|Recombinant

Western blot - Anti-GNAZ antibody [EPR8654] (AB154846)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/10000 - 1/50000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" }, "Mouse": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/10000 - 1/50000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" }, "Rat": { "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/10000 - 1/50000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>" } } }
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제품 세부 정보

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

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특성 및 보관 정보

제형
Liquid
보관 버퍼
pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
배송 시 보관 조건
Conditional Ambient
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

The CTRL protein also known as chymotrypsin-like protease CTRL-1 functions primarily as a serine protease. It exhibits a catalytic domain typical of the Chymotrypsin family of serine proteases. With a mass of approximately 29 kDa CTRL is expressed prominently in pancreatic tissue but can also be found in other tissues at lower levels. It plays a role in protein degradation by cleaving at specific amino acid sites.
Biological function summary

The serine protease activity of CTRL contributes to the digestion process by breaking down protein chains into smaller peptides. It does not work alone but rather as part of a larger complex. This involvement makes it integral to maintaining protein homeostasis in the body. It's expressed in various cellular processes that require the precise breakdown of polypeptides emphasizing its importance in tissue maintenance and repair.

Pathways

CTRL is involved in the proteolytic pathway facilitating the breakdown of dietary proteins into absorbable units. It collaborates closely with other proteases such as trypsin that complement its function by targeting different peptide bonds. Additionally CTRL takes part in cellular metabolism pathways where it assists in processing proteins needed for cellular activities.

Dysfunctional CTRL activity associates with digestive disorders such as pancreatitis. An imbalance in its activity can also contribute to the development of pancreatic insufficiencies. In these contexts CTRL interacts with proteins like elastase where altered activity levels can exacerbate tissue damage during inflammatory conditions. Understanding CTRL's precise role provides insights into potential therapeutic targets for managing certain pathologies.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

See full target information CTRL
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

International heart journal 64:750-758 PubMed37518356

2023

LIM Homeobox 2 Increases Adhesion-Regulating Molecule 1 Transcription to Facilitate the Pathological Progression of Oxidized Low-Density Lipoprotein-Stimulated Atherosclerotic Cell Models.

Applications

Unspecified application

Species

Unspecified reactive species

Junqi Xiao,Yang Xie,Qing Duan,Tao Liu,Rong Ye,Xunhong Duan,Zhibiao Le,Nan Deng,Fengen Liu
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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