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AB244755

Anti-CXCL15 antibody [EPR20936-67] - BSA and Azide free (Capture)

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Rabbit Recombinant Monoclonal CXCL15 antibody. Carrier free. Suitable for sELISA and reacts with Mouse samples.
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Sandwich ELISA - Anti-CXCL15 antibody [EPR20936-67] - BSA and Azide free (Capture) (AB244755)
  • sELISA

Supplier Data

Sandwich ELISA - Anti-CXCL15 antibody [EPR20936-67] - BSA and Azide free (Capture) (AB244755)

Representative standard curve from corresponding SimpleStep ELISA® Kit (ab234567).

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR20936-67

Isotype

IgG

Carrier free

Yes

Reacts with

Mouse

Applications

sELISA

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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보완 제품

Assay Kits

AB234567

Mouse CXCL15 ELISA Kit

Recombinant|SimpleStep

Sandwich ELISA - Mouse CXCL15 ELISA Kit (AB234567)

  • 0
  • 0
Sample Prep & Detection Kits

AB201801

DyLight® 594 Conjugation Kit (Fast) - Lightning-Link®

Fluorescence Microscopy - DyLight® 594 Conjugation Kit (Fast) - Lightning-Link® (AB201801)

  • 0
  • 0
Sample Prep & Detection Kits

AB269903

Gold-Maleimide Conjugation Kit (10nm, 20 OD)

Lateral flow assay - Gold-Maleimide Conjugation Kit (10nm, 20 OD) (AB269903)

  • 0
  • 0
Primary Antibodies

AB6326

Anti-BrdU antibody [BU1/75 (ICR1)] - Proliferation Marker

Flow Cytometry (Intracellular) - Anti-BrdU antibody [BU1/75 (ICR1)] - Proliferation Marker (AB6326)

  • 5
  • 104
Primary Antibodies

AB237709

Anti-CD8 alpha antibody [CAL66]

BOND RX™ Validated|20ul selling size|RabMAb|Advanced Validation|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-CD8 alpha antibody [CAL66] (AB237709)

  • 4
  • 3
Primary Antibodies

AB16669

Anti-CD3 epsilon antibody [SP7]

BOND RX™ Validated|RabMAb|Advanced Validation|Recombinant|Lab Essentials|20ul selling size

Multiplex immunohistochemistry - Anti-CD3 epsilon antibody [SP7] (AB16669)

  • 4
  • 80
Primary Antibodies

AB214421

Anti-PD1 antibody [EPR20665]

20ul selling size|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PD1 antibody [EPR20665] (AB214421)

  • 4
  • 3
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "sELISA" : {"fullname" : "Sandwich ELISA", "shortname":"sELISA"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "sELISA-species-checked": "guaranteed", "sELISA-species-dilution-info": "", "sELISA-species-notes": "<p></p>" } } }
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제품 세부 정보

ab244755 is a BSA and Azide Free antibody supplied in an unconjugated format and it is suitable for sandwich ELISAs to quantify Mouse CXCL15. The recommended pair for sandwich ELISA is:
Capture: ab244755, Mouse CXCL15 Capture Antibody (unconjugated)
Detector: ab245025, Mouse CXCL15 Detector Antibody (unconjugated)
The reference range value is 25 - 4800 pg/ml.

Patented technology
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

  • - High batch-to-batch consistency and reproducibility
  • - Improved sensitivity and specificity
  • - Long-term security of supply
  • - Animal-free batch production

For more information, read more on recombinant antibodies.

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

Sandwich ELISA
The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Please note that the range provided for this antibody is only an estimation based on the performance of the product using the recommended antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody in your assay.

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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
Constituents: PBS
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

CXCL15 also known as lungkine is a small cytokine belonging to the CXC chemokine family. This protein exhibits a molecular mass of approximately 9 kDa. CXCL15 is expressed mainly in epithelial cells of the lung where it facilitates the recruitment of neutrophils. Unlike some other cytokines lungkine is produced constitutively and does not require induction by inflammatory stimuli. Its role as a chemokine indicates a specific involvement in respiratory immune responses.
Biological function summary

CXCL15 is involved in the recruitment and activation of neutrophils playing a pivotal role in the innate immune defense. It does not form a complex; instead it functions as a soluble signal guiding the migration of immune cells to sites of inflammation in the lungs. CXCL15 contributes to the body's defense mechanisms against infection. Its interaction with neutrophils is important for maintaining pulmonary health and responding to pathogenic challenges.

Pathways

The recruitment activity of CXCL15 is involved in chemokine signaling and immune response pathways. CXCL15 interacts with G protein-coupled receptors on neutrophils to drive chemotaxis the directed movement of cells toward areas of infection. This pathway involves cooperation with other cytokines such as CXCL1 and CXCL8 which also play roles in neutrophil trafficking and activation in inflammatory scenarios.

CXCL15 has a relationship with chronic obstructive pulmonary disease (COPD) and acute lung injury. Elevated levels of CXCL15 may exacerbate inflammatory conditions contributing to the progression and severity of these diseases. In COPD CXCL15 influences neutrophil accumulation in the airways often linked with other chemokines like IL-8. Understanding its role may offer insight into therapeutic strategies targeting excessive neutrophilic infiltration in lung-related disorders.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Chemotactic for neutrophils. Involved in lung-specific neutrophil trafficking during normal and inflammatory conditions.
See full target information Cxcl15

대체 명칭 보기

Scyb15, Cxcl15, C-X-C motif chemokine 15, Lungkine, Small-inducible cytokine B15
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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