AB238013

Anti-Cytokeratin 6a antibody [KRT6A/2368]

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(3 제품이 사용된 논문 )

Mouse Monoclonal K2C6A antibody. Suitable for IHC-P, Protein Array and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human KRT6A.

대체 명칭 보기

K6A, KRT6D, KRT6A, Cytokeratin-6A, Cytokeratin-6D, Keratin-6A, Type-II keratin Kb6, CK-6A, CK-6D

4 이미지

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)

Formalin-fixed, paraffin-embedded human prostate carcinoma tissue stained for Cytokeratin 6 using ab238013 at 2 μg/ml in immunohistochemical analysis.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)

Formalin-fixed, paraffin-embedded human basal cell carcinoma tissue stained for Cytokeratin 6 using ab238013 at 2 μg/ml in immunohistochemical analysis.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)

Formalin-fixed, paraffin-embedded human basal cell tissue stained for Cytokeratin 6 using ab238013 at 2 μg/ml in immunohistochemical analysis.

Protein Array - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)

Protein Array

Unknown

Protein Array - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)

ab238013 was tested in protein array against over 19000 different full-length human proteins.
Z- and S- Score : The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target.
A MAb is specific to its intended target if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

주요 정보

Host species

Mouse

Clonality

Monoclonal

Clone number

KRT6A/2368

Isotype

IgG2a

Light chain 타입

kappa

Carrier free

Reacts with

Human

Applications

IHC-P, Protein Array

applications

Immunogen

Recombinant Full Length Protein corresponding to Human KRT6A.

P02538

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ProteinArray" : {"fullname" : "Protein Array", "shortname":"Protein Array"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1-2 µg/mL", "IHCP-species-notes": "<p>Incubate with primary antibody for 30 minutes at RT.</p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "ProteinArray-species-checked": "testedAndGuaranteed", "ProteinArray-species-dilution-info": "", "ProteinArray-species-notes": "<p></p>" } } }

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Protein A/G

Purification 관련 사항

Purified from Bioreactor Concentrate by Protein A/G.

보관 버퍼

pH: 7.2 - 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 0.05% BSA

배송 시 보관 조건

Blue Ice

적절한 단기 보관 기간

1-2 weeks

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair.

See full target information KRT6A

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제품이 사용된 논문 (3)

Recent publications for all applications. Explore the 전체 목록 and refine your search

The Journal of investigative dermatology 143:2052-2064.e5 PubMed37044260

2023

Bacterial Pyocyanin Inducible Keratin 6A Accelerates Closure of Epithelial Defect under Conditions of Mitochondrial Dysfunction.

Applications

Unspecified application

Species

Unspecified reactive species

Subhadip Ghatak,Craig Hemann,James Boslett,Kanhaiya Singh,Anu Sharma,Mohamed S El Masry,Ahmed Safwat Abouhashem,Nandini Ghosh,Shomita S Mathew-Steiner,Sashwati Roy,Jay L Zweier,Chandan K Sen

Cell cycle (Georgetown, Tex.) 21:1479-1490 PubMed35311447

2022

expedites bladder cancer progression, regulated by miR-31-5p.

Applications

Unspecified application

Species

Unspecified reactive species

Yuan Chen,Shiben Ji,Jianxin Ying,Yongchang Sun,Jun Liu,Guohong Yin

Hepatology (Baltimore, Md.) 74:847-863 PubMed33554350

2021

The Clinical Significance of Hepatic CD69 CD103 CD8 Resident-Memory T Cells in Autoimmune Hepatitis.

Applications

Unspecified application

Species

Unspecified reactive species

Zhengrui You,You Li,Qixia Wang,Zhibin Zhao,Yikang Li,Qiwei Qian,Bo Li,Jun Zhang,Bingyuan Huang,Jubo Liang,Ruiling Chen,Zhuwan Lyu,Yong Chen,Min Lian,Xiao Xiao,Qi Miao,Jingyuan Fang,Zhexiong Lian,M Eric Gershwin,Ruqi Tang,Xiong Ma

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Cytokeratin 6a antibody [KRT6A/2368]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)

Protein Array - Anti-Cytokeratin 6a antibody [KRT6A/2368] (AB238013)

주요 정보

Host species

Clonality

Clone number

Isotype

Light chain 타입

Carrier free

Reacts with

Applications

Immunogen

대체품

Primary Antibodies

보완 제품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

Purification 관련 사항

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 기간

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

제품 프로토콜

타겟 정보

제품이 사용된 논문 (3)

Product promise