AB169783

Anti-DC-SIGNR antibody [EPR11211]

RabMAb
Recombinant
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(6 제품이 사용된 논문 )

Rabbit Recombinant Monoclonal DC-SIGNR antibody. Suitable for IHC-P, WB and reacts with Human samples. Cited in 6 publications.

대체 명칭 보기

CD299, CD209L, CD209L1, CLEC4M, C-type lectin domain family 4 member M, CD209 antigen-like protein 1, DC-SIGN-related protein, Dendritic cell-specific ICAM-3-grabbing non-integrin 2, Liver/lymph node-specific ICAM-3-grabbing non-integrin, DC-SIGNR, DC-SIGN2, L-SIGN

6 이미지

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DC-SIGNR antibody [EPR11211] (AB169783)

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DC-SIGNR antibody [EPR11211] (AB169783)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human liver tissue, labeling DC-SIGNR using ab169783 at a 1/100 dilution.

Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DC-SIGNR antibody [EPR11211] (AB169783)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human placenta tissue sections labeling DC-SIGNR with purified ab169783 at 1/500 dilution (0.502 μg/ml). Heat mediated antigen retrieval using Bond™ Epitope Retrieval Solution 1 (pH 6.0). Rabbit specific IHC polymer detection kit HRP/DAB (ab209101) was used as the secondary antibody. Negative control : PBS instead of the primary antibody. Hematoxylin was used as a counterstain.

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DC-SIGNR antibody [EPR11211] (AB169783)

Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human placenta tissue, labeling DC-SIGNR using unpurified ab169783 at a 1/100 dilution.

Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Lab

Western blot - Anti-DC-SIGNR antibody [EPR11211] (AB169783)

All lanes:

Western blot - Anti-DC-SIGNR antibody [EPR11211] (ab169783) at 1/10000 dilution

All lanes:

Human liver lysates at 15 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG (HRP) with minimal cross-reactivity with human IgG at 1/2000 dilution

Predicted band size: 45 kDa

Observed band size: 45 kDa

false

Lab

Western blot - Anti-DC-SIGNR antibody [EPR11211] (AB169783)

All lanes:

Western blot - Anti-DC-SIGNR antibody [EPR11211] (ab169783) at 1/10000 dilution

All lanes:

Human kidney lysates at 15 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG (HRP) with minimal cross-reactivity with human IgG at 1/2000 dilution

Predicted band size: 45 kDa

Observed band size: 45 kDa

false

Lab

Western blot - Anti-DC-SIGNR antibody [EPR11211] (AB169783)

All lanes:

Western blot - Anti-DC-SIGNR antibody [EPR11211] (ab169783) at 1/1000 dilution

All lanes:

Human placenta lysates at 15 µg

Secondary

All lanes:

Goat Anti-Rabbit IgG (HRP) with minimal cross-reactivity with human IgG at 1/2000 dilution

Predicted band size: 45 kDa

Observed band size: 45 kDa

false

주요 정보

Host species

Rabbit

Clonality

Monoclonal

Clone number

EPR11211

Isotype

IgG

Carrier free

Reacts with

Human

Applications

IHC-P, WB

applications

Immunogen

The exact immunogen used to generate this antibody is proprietary information.

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "IP" : {"fullname" : "Immunoprecipitation", "shortname":"IP"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/500", "IHCP-species-notes": "For unpurified use at 1/100 - 1/250 Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/10000", "WB-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Chimpanzee": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Gorilla": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "IP-species-checked": "notRecommended", "IP-species-dilution-info": "", "IP-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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제품 세부 정보

Species reactivity
Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species.
Please contact us for more information.

Patented technology
Our RabMAb^® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb^® patents.

What are the advantages of a recombinant monoclonal antibody?
This product is a recombinant monoclonal antibody, which offers several advantages including:

- High batch-to-batch consistency and reproducibility
- Improved sensitivity and specificity
- Long-term security of supply
- Animal-free batch production

For more information, read more on recombinant antibodies.

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Protein A

보관 버퍼

Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA

배송 시 보관 조건

Conditional Ambient

적절한 단기 보관 기간

1-2 weeks

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates.. (Microbial infection) Acts as an attachment receptor for Ebolavirus.. (Microbial infection) Acts as an attachment receptor for Hepatitis C virus.. (Microbial infection) Acts as an attachment receptor for HIV-1.. (Microbial infection) Acts as an attachment receptor for Human coronavirus 229E.. (Microbial infection) Acts as an attachment receptor for Human cytomegalovirus/HHV-5.. (Microbial infection) Acts as an attachment receptor for Influenzavirus.. (Microbial infection) Acts as an attachment receptor for SARS-CoV.. (Microbial infection) Acts as an attachment receptor for West-nile virus.. (Microbial infection) Acts as an attachment receptor for Japanese encephalitis virus.. (Microbial infection) Acts as an attachment receptor for Marburg virus glycoprotein.. (Microbial infection) Recognition of M.bovis by dendritic cells may occur partially via this molecule.

See full target information CLEC4M

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제품이 사용된 논문 (6)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Frontiers in microbiology 15:1452739 PubMed39749135

2025

Limitations of a proper SFTSV mouse model using human C-type lectin receptors.

Applications

Unspecified application

Species

Unspecified reactive species

You-Min Kim,Hyo-Jin Ro,Jae Hoon Lee,Yaechan Song,Han-Woong Lee,Nam-Hyuk Cho

International journal of general medicine 16:1317-1332 PubMed37089135

2023

Investigation of Diagnostic and Prognostic Value of CLEC4M of Non-Small Cell Lung Carcinoma Associated with Immune Microenvironment.

Applications

Unspecified application

Species

Unspecified reactive species

Huan Liu,Zhiping Yu,Yueguang Liu,Mingzhen Li,Cheng Chen,Zhiyu Zhu,Fang Liu,Liming Tan

Immunity 54:1304-1319.e9 PubMed34048708

2021

SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2.

Applications

Unspecified application

Species

Unspecified reactive species

Qiao Lu,Jia Liu,Shuai Zhao,Maria Florencia Gomez Castro,Maudry Laurent-Rolle,Jianbo Dong,Xiaojuan Ran,Payal Damani-Yokota,Hongzhen Tang,Triantafyllia Karakousi,Juhee Son,Maria E Kaczmarek,Ze Zhang,Stephen T Yeung,Broc T McCune,Rita E Chen,Fei Tang,Xianwen Ren,Xufeng Chen,Jack C C Hsu,Marianna Teplova,Betty Huang,Haijing Deng,Zhilin Long,Tenny Mudianto,Shumin Jin,Peng Lin,Jasper Du,Ruochen Zang,Tina Tianjiao Su,Alberto Herrera,Ming Zhou,Renhong Yan,Jia Cui,James Zhu,Qiang Zhou,Tao Wang,Jianzhu Ma,Sergei B Koralov,Zemin Zhang,Iannis Aifantis,Leopoldo N Segal,Michael S Diamond,Kamal M Khanna,Kenneth A Stapleford,Peter Cresswell,Yue Liu,Siyuan Ding,Qi Xie,Jun Wang

Oncology letters 19:1711-1720 PubMed32194663

2020

High expression levels of CLEC4M indicate poor prognosis in patients with hepatocellular carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Liuping Luo,Lihong Chen,Kun Ke,Bixing Zhao,Lili Wang,Cuilin Zhang,Fei Wang,Naishun Liao,Xiaoyuan Zheng,Xiaolong Liu,Yingchao Wang,Jingfeng Liu

Oncology letters 19:69-76 PubMed31897116

2020

Decreased DC-SIGNR expression in hepatocellular carcinoma predicts poor patient prognosis.

Applications

Unspecified application

Species

Unspecified reactive species

Hai-Bing Xia,Hui-Ju Wang,Shu-Shu Song,Jun-Gang Zhang,Xiang-Lei He,Zhi-Ming Hu,Cheng-Wu Zhang,Dong-Sheng Huang,Xiao-Zhou Mou

Oncology letters 14:2813-2821 PubMed28927040

2017

Overexpression of dendritic cell-specific intercellular adhesion molecule-3-grabbing nonintegrin-related protein in cervical cancer and correlation with squamous cell carcinoma antigen.

Applications

Unspecified application

Species

Unspecified reactive species

Xiangdong Wang,Yangmei Jiang,Menglang Yuan,Chunlin Chen,Keyong Wang,Qianshi Zhang,Yunfei Zuo,Shuangyi Ren

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

자세한 내용은 이용 약관을 확인해 주세요.

Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-DC-SIGNR antibody [EPR11211]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DC-SIGNR antibody [EPR11211] (AB169783)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DC-SIGNR antibody [EPR11211] (AB169783)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DC-SIGNR antibody [EPR11211] (AB169783)

Western blot - Anti-DC-SIGNR antibody [EPR11211] (AB169783)

Western blot - Anti-DC-SIGNR antibody [EPR11211] (AB169783)

Western blot - Anti-DC-SIGNR antibody [EPR11211] (AB169783)

관련 conjugated 항체와 다양한 조성의 항체 (1)

주요 정보

Host species

Clonality

Clone number

Isotype

Carrier free

Reacts with

Applications

Immunogen

대체품

Primary Antibodies

보완 제품

Assay Kits

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

제품 세부 정보

특성 및 보관 정보

제형

Purification 테크닉

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 기간

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

제품 프로토콜

타겟 정보

제품이 사용된 논문 (6)

Product promise