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AB84416

Anti-DEGA antibody

3

(2 리뷰들)

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(2 제품이 사용된 논문 )

Rabbit Polyclonal DEGA antibody. Suitable for IHC-P and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Synthetic Peptide within Human AMIGO2.
1 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DEGA antibody (AB84416)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DEGA antibody (AB84416)

ab84416 at 1/100 dilution staining DEGA in human breast carcinoma by Immunohistochemistry, Formalin-fixed, Paraffin-embedded tissue.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Synthetic Peptide within Human AMIGO2. The exact immunogen used to generate this antibody is proprietary information.

Q86SJ2

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대체품

Primary Antibodies

AB216591

Anti-DEGA antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DEGA antibody (AB216591)

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보완 제품

Assay Kits

AB313506

Human DEGA ELISA Kit

Sandwich ELISA - Human DEGA ELISA Kit (AB313506)

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Primary Antibodies

AB118458

Anti-SEMAC antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SEMAC antibody (AB118458)

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Primary Antibodies

AB307692

Anti-Claudin 1 antibody [EPR25359-48]

BOND RX™ Validated|20ul selling size|RabMAb|Recombinant|KO Validated

Immunocytochemistry/ Immunofluorescence - Anti-Claudin 1 antibody [EPR25359-48] (AB307692)

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Proteins & Peptides

AB276581

Recombinant Human DEGA protein (His tag)

SDS-PAGE - Recombinant Human DEGA protein (His tag) (AB276581)

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/100 - 1/500", "IHCP-species-notes": "<p></p>" } } }
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특성 및 보관 정보

제형
Lyophilized
Reconstitution
reconstitute with water at 200µL
Purification 테크닉
Affinity purification Immunogen
Purification 관련 사항
ab84416 is by a peptide affinity column.
보관 버퍼
Preservative: 0.02% Sodium azide Constituents: 2% BSA
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

The DEGA protein also known as DEGA-1 functions mechanically as a transmembrane protein involved in cellular adhesion. It has a mass of approximately 55 kDa and expresses widely in epithelial tissues where cellular interactions requiring adhesion are important for tissue integrity. DEGA is present in various cell types indicating its broad physiological relevance across tissues.
Biological function summary

This protein plays a role in modulating cell adhesion dynamics and contributes to tissue organization and stability. It forms part of adhesion complexes at the cellular surface interacting with cytoskeletal elements. Through these complexes DEGA helps maintain mechanical stability and signaling within epithelial cells making it an important component in tissue maintenance and repair.

Pathways

DEGA participates in cellular adhesion and signaling pathways essential for maintaining epithelial integrity. It interacts with proteins such as E-cadherin a well-known adhesion molecule forming a network that reinforces adhesion. This protein also integrates signals for pathway regulation playing a critical role in maintaining homeostasis in the epithelial layer.

DEGA is linked to epithelial-related conditions such as carcinomas where altered adhesion contributes to disease progression. It interacts with proteins involved in tumorigenesis such as E-cadherin and beta-catenin. The loss or dysfunction of DEGA can lead to disrupted cell adhesion contributing to the invasive characteristics of cancerous cells highlighting its importance in disease pathology.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Required for depolarization-dependent survival of cultured cerebellar granule neurons. May mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. May contribute to signal transduction through its intracellular domain. May be required for tumorigenesis of a subset of gastric adenocarcinomas.
See full target information AMIGO2

대체 명칭 보기

ALI1, AMIGO2, Amphoterin-induced protein 2, AMIGO-2, Alivin-1, Differentially expressed in gastric adenocarcinomas, DEGA
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제품이 사용된 논문 (2)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Differentiation; research in biological diversity 128:83-100 PubMed36114074

2022

Steroidogenic factor 1 (NR5A1) induces multiple transcriptional changes during differentiation of human gonadal-like cells.

Applications

Unspecified application

Species

Unspecified reactive species

Kirsi Sepponen,Karolina Lundin,Dawit A Yohannes,Sanna Vuoristo,Diego Balboa,Matti Poutanen,Claes Ohlsson,Steinar Hustad,Ersilia Bifulco,Pauliina Paloviita,Timo Otonkoski,Olli Ritvos,Kirsi Sainio,Juha S Tapanainen,Timo Tuuri

Frontiers in cardiovascular medicine 9:884031 PubMed35711359

2022

Mechanical Strain Induces Transcriptomic Reprogramming of Saphenous Vein Progenitors.

Applications

Unspecified application

Species

Unspecified reactive species

Davide Maselli,Gloria Garoffolo,Giada Andrea Cassanmagnago,Rosa Vono,Matthijs S Ruiter,Anita C Thomas,Paolo Madeddu,Maurizio Pesce,Gaia Spinetti
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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