Rabbit Polyclonal DIS3L antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human DIS3L aa 1 to C-terminus.
대체 명칭 보기
DIS3L1, KIAA1955, DIS3L, DIS3-like exonuclease 1
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DIS3L antibody (AB235532)
Paraffin-embedded human adrenal gland tissue stained for DIS3L using ab235532 at 1/100 dilution in immunohistochemical analysis.
- IHC-P
Supplier Data
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-DIS3L antibody (AB235532)
Paraffin-embedded human colon cancer tissue stained for DIS3L using ab235532 at 1/100 dilution in immunohistochemical analysis.
Reactivity 정보
특성 및 보관 정보
제형
Purification 테크닉
Purification 관련 사항
보관 버퍼
배송 시 보관 조건
적절한 단기 보관 기간
적절한 단기 보관 조건
적절한 장기 보관 조건
분주 정보
보관 정보
추가 정보
This supplementary information is collated from multiple sources and compiled automatically.
Biological function summary
The mechanisms of DIS3L contribute significantly to the RNA exosome complex a multiprotein complex responsible for processing and degrading RNA molecules. This involvement suggests that DIS3L plays a part in the quality control of RNA ensuring the proper turnover and maturation of various RNA species. By participating in the RNA exosome complex DIS3L contributes to critical cellular processes such as gene expression regulation and RNA surveillance.
Pathways
DIS3L integrates into the RNA degradation pathways and the nonsense-mediated mRNA decay (NMD) pathway. These pathways play essential roles in maintaining cellular RNA balance and regulating gene expression. In the RNA degradation pathway DIS3L acts alongside proteins like SKI2 which further highlights its involvement in preserving RNA homeostasis. DIS3L's function within these pathways underlines its importance in controlling aberrant RNA molecules that can influence cell fate and function.
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타겟 정보
제품이 사용된 논문 (1)
Recent publications for all applications. Explore the 전체 목록 and refine your search
Frontiers in oncology 11:629974 PubMed33968728
2021
Applications
Unspecified application
Species
Unspecified reactive species
Product promise
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