AB233003

Anti-Dishevelled / Dvl1 antibody

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(9 제품이 사용된 논문 )

Rabbit Polyclonal Dishevelled / Dvl1 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 9 publications. Immunogen corresponding to Recombinant Fragment Protein within Human DVL1 aa 150 to C-terminus.

대체 명칭 보기

Segment polarity protein dishevelled homolog DVL-1, Dishevelled-1, DSH homolog 1, DVL1

4 이미지

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Dishevelled / Dvl1 antibody (AB233003)

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Dishevelled / Dvl1 antibody (AB233003)

Formalin-fixed, paraffin-embedded human glioma tissue stained for Dishevelled / Dvl1 using ab233003 at 20 ug/ml in immunohistochemical analysis. DAB staining.

IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Dishevelled / Dvl1 antibody (AB233003)

Formalin-fixed, paraffin-embedded human liver tissue stained for Dishevelled / Dvl1 using ab233003 at 20 ug/ml in immunohistochemical analysis. DAB staining.

Supplier Data

Western blot - Anti-Dishevelled / Dvl1 antibody (AB233003)

All lanes:

Western blot - Anti-Dishevelled / Dvl1 antibody (ab233003) at 2 µg/mL

All lanes:

Human lung tissue

Secondary

All lanes:

HRP-Linked Guinea pig anti-rabbit at 1/2000 dilution

Predicted band size: 75 kDa

false

Supplier Data

Western blot - Anti-Dishevelled / Dvl1 antibody (AB233003)

All lanes:

Western blot - Anti-Dishevelled / Dvl1 antibody (ab233003) at 2 µg/mL

All lanes:

Recombinant human Dishevelled / Dvl1 protein

Predicted band size: 75 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human DVL1 aa 150 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

O14640

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1-5 µg/mL", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "5-20 µg/mL", "IHCP-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Chimpanzee": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Immunogen

Purification 관련 사항

Antigen-specific affinity chromatography followed by Protein A affinity chromatography.

보관 버퍼

pH: 7.4 Preservative: 0.011% Proclin 300 Constituents: PBS, 55.77% Glycerol (glycerin, glycerine)

배송 시 보관 조건

Blue Ice

적절한 단기 보관 기간

1-2 weeks

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ).

See full target information DVL1

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제품이 사용된 논문 (9)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Nature communications 16:4124 PubMed40319020

2025

Non-canonical Wnt signaling promotes epithelial fluidization in the repairing airway.

Applications

Unspecified application

Species

Unspecified reactive species

Daniel Jun-Kit Hu,Xiaoyu Tracy Cai,Jesse Simons,Jina Yun,Justin Elstrott,Heinrich Jasper

Journal of neuroinflammation 19:129 PubMed35658977

2022

DKK3 ameliorates neuropathic pain via inhibiting ASK-1/JNK/p-38-mediated microglia polarization and neuroinflammation.

Applications

Unspecified application

Species

Unspecified reactive species

Long-Qing Zhang,Shao-Jie Gao,Jia Sun,Dan-Yang Li,Jia-Yi Wu,Fan-He Song,Dai-Qiang Liu,Ya-Qun Zhou,Wei Mei

Scientific reports 12:8388 PubMed35589804

2022

DVL1 and DVL3 require nuclear localisation to regulate proliferation in human myoblasts.

Applications

Unspecified application

Species

Unspecified reactive species

Johanna Pruller,Nicolas Figeac,Peter S Zammit

International journal of molecular sciences 23: PubMed35163107

2022

Bilateral Meningioma: A Case Report and Review of the Literature.

Applications

Unspecified application

Species

Unspecified reactive species

Anja Bukovac,Hana Panić,Tomislava Mrgan,Nika Šlaus,Anja Kafka,Niko Njirić,Nives Pećina-Šlaus

International journal of molecular sciences 22: PubMed34769425

2021

Decoding the Role of DVL1 in Intracranial Meningioma.

Applications

Unspecified application

Species

Unspecified reactive species

Anja Bukovac,Katarina Dragičević,Anja Kafka,Darko Orešković,Sanja Cesarec-Augustinović,Nives Pećina-Šlaus

Cancer medicine 10:7383-7394 PubMed34547189

2021

Identification of colon tumor marker NKD1 via integrated bioinformatics analysis and experimental validation.

Applications

Unspecified application

Species

Unspecified reactive species

Yue Wang,Chunxia Yang,Wenjing Li,Ying Shen,Jianzhong Deng,Wenbin Lu,Jianhua Jin,Yongping Liu,Qian Liu

Molecular oncology 15:3490-3512 PubMed34288405

2021

FUBP1 promotes colorectal cancer stemness and metastasis via DVL1-mediated activation of Wnt/β-catenin signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Haofan Yin,Tianxiao Gao,Jinye Xie,Zhijian Huang,Xiaoyan Zhang,Fengyu Yang,Weiwei Qi,Zhonghan Yang,Ti Zhou,Guoquan Gao,Xia Yang

Scientific reports 10:17443 PubMed33060778

2020

Cir-ITCH inhibits gastric cancer migration, invasion and proliferation by regulating the Wnt/β-catenin pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Yang Peng,Hong Hong Wang

Oncology reports : PubMed31524268

2019

Casiopeina II‑gly acts on lncRNA MALAT1 by miR‑17‑5p to inhibit FZD2 expression via the Wnt signaling pathway during the treatment of cervical carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Yunsheng Xu,Qianwen Zhang,Fan Lin,Li Zhu,Fangfang Huang,Liang Zhao,Rongying Ou

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-Dishevelled / Dvl1 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Dishevelled / Dvl1 antibody (AB233003)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Dishevelled / Dvl1 antibody (AB233003)

Western blot - Anti-Dishevelled / Dvl1 antibody (AB233003)

Western blot - Anti-Dishevelled / Dvl1 antibody (AB233003)

주요 정보

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

보완 제품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

Purification 관련 사항

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 기간

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

제품 프로토콜

타겟 정보

제품이 사용된 논문 (9)

Product promise