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AB110112

Anti-EMX2 antibody

3

(2 리뷰들)

|

(1 출판물)

Rabbit Polyclonal EMX2 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human EMX2.

대체 명칭 보기

Homeobox protein EMX2, Empty spiracles homolog 2, Empty spiracles-like protein 2, EMX2

1 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EMX2 antibody (AB110112)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-EMX2 antibody (AB110112)

ab110112, at 1/50 dilution, staining EMX2 in paraffin embedded Human brain tissue by Immunohistochemistry in the presence (right panel) or absence (left panel) of immunizing peptide.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

IHC-P

applications

Immunogen

Synthetic Peptide within Human EMX2. The exact immunogen used to generate this antibody is proprietary information.

Q04743

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대체품

Primary Antibodies

AB171818

Anti-EMX2 antibody

  • 0
  • 0
Primary Antibodies

AB94713

Anti-EMX2 antibody

Western blot - Anti-EMX2 antibody (AB94713)

  • 5
  • 4

보완 제품

Primary Antibodies

AB22758

Anti-Nucleolin antibody

BOND RX™ Validated

Western blot - Anti-Nucleolin antibody (AB22758)

  • 4
  • 8
Primary Antibodies

AB196868

Anti-FOXG1 antibody [EPR18987]

20ul selling size|RabMAb|Recombinant|Advanced Validation

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FOXG1 antibody [EPR18987] (AB196868)

  • 4
  • 1
Primary Antibodies

AB76013

Anti-TTF1/Nkx2-1 antibody [EP1584Y]

RabMAb|Recombinant|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-TTF1/Nkx2-1 antibody [EP1584Y] (AB76013)

  • 5
  • 18
Primary Antibodies

AB79389

Anti-Pax2 antibody [EP3251]

20ul selling size|BOND RX™ Validated|RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Pax2 antibody [EP3251] (AB79389)

  • 4
  • 11
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/50 - 1/100", "IHCP-species-notes": "<p></p> Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol." }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
Purification 관련 사항
ab110112 was affinity purified from rabbit antiserum by affinity chromatography using epitope specific immunogen.
보관 버퍼
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
보관 정보
Stable for 12 months at -20°C
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

EMX2 also known as Empty Spiracles Homeobox 2 functions as a homeobox transcription factor. This protein has a mass of approximately 33 kilodaltons. It is mainly expressed in the developing brain where it plays an important role in brain morphogenesis and neuronal development. EMX2 also presents in other tissues such as the kidney and reproductive organs where it contributes to organogenesis.
Biological function summary

The EMX2 protein influences developmental processes by regulating gene expression essential for cellular differentiation and tissue development. It does not belong to a larger complex but interacts with various transcription factors to exert its regulatory functions. EMX2 modulates important aspects of brain development guiding the patterning and regional specification within the cerebral cortex.

Pathways

EMX2 plays an influential role in the Wnt signaling pathway which is key to developmental processes like cell fate determination proliferation and migration. Additionally EMX2 is involved in the regulation of neural lineage specification through its interaction with other proteins such as PAX6. Together these proteins create a regulatory network that controls neural precursor cell proliferation and differentiation.

EMX2 has implications in neurological disorders. Abnormal expression or mutations in the EMX2 gene can contribute to developmental brain disorders such as schizencephaly which involves abnormal clefts or deep grooves in the cerebral hemispheres. The protein also links to cancer pathways notably in gliomas where dysregulation of EMX2 expression can affect tumor progression. Connections between EMX2 and proteins like GLI1 in the Glioma signaling pathway provide insights into its role in oncogenesis.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Transcription factor, which in cooperation with EMX1, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combination with OTX1/2 to specify cell fates in the developing central nervous system. In the inner ear, it controls the distribution of GPR156 at hair cell boundaries, and regulates the organization of stereociliary bundles in opposite orientations across the line of polarity reversal (LPR).
See full target information EMX2
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Reproduction (Cambridge, England) 151:673-81 PubMed27002001

2016

Critical role of Emx2 in the pluripotency - differentiation transition in male gonocytes via regulation of FGF9/NODAL pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Ma Tian-Zhong,Chen Bi,Zhang Ying,Jing Xia,Peng Cai-Ling,Zhang Yun-Shan,Huang Mei-Wen,Niu Yan-Ru
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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