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AB308408

Anti-Enterovirus D68 VP1 antibody [GT1843] - BSA and Azide free

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Mouse Monoclonal Enterovirus D68 VP1 antibody antibody. Carrier free. Suitable for I-ELISA, WB and reacts with Recombinant full length protein - Enterovirus D68, Transfected cell line - Enterovirus D68 samples.
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Sandwich ELISA - Anti-Enterovirus D68 VP1 antibody [GT1843] - BSA and Azide free (AB308408)
  • sELISA

Supplier Data

Sandwich ELISA - Anti-Enterovirus D68 VP1 antibody [GT1843] - BSA and Azide free (AB308408)

Sandwich ELISA detection of recombinant full-length VP1 protein(s) derived from different strains of Enterovirus (D68; 71) using antibodies as below : Capture : ab308408 (5 μg/mL) Detection : ab308217 (1 μg/mL)

Indirect ELISA - Anti-Enterovirus D68 VP1 antibody [GT1843] - BSA and Azide free (AB308408)
  • I-ELISA

Supplier Data

Indirect ELISA - Anti-Enterovirus D68 VP1 antibody [GT1843] - BSA and Azide free (AB308408)

Indirect ELISA analysis was performed by coating the plate with recombinant full-length enterovirus D68 VP1 (4000-62.5 ng/mL). Coated protein was probed with Enterovirus D68 VP1 antibody [GT1843] (ab308408) (1 μg/mL). Goat anti-mouse IgG antibody (HRP) (1/10000) was used to detect the bound primary antibody.

주요 정보

Host species

Mouse

Clonality

Monoclonal

Clone number

GT1843

Isotype

IgG2a

Carrier free

Yes

Reacts with

Enterovirus D68

Applications

I-ELISA, WB

applications

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보완 제품

Primary Antibodies

AB308217

Anti-Enterovirus D68 VP1 antibody [HL1997]

Recombinant

Sandwich ELISA - Anti-Enterovirus D68 VP1 antibody [HL1997] (AB308217)

  • 5
  • 1
Primary Antibodies

AB2386

Anti-Transglutaminase 2 antibody [CUB 7402]

KO Validated

Western blot - Anti-Transglutaminase 2 antibody [CUB 7402] (AB2386)

  • 5
  • 9
Primary Antibodies

AB137055

Anti-ATP1B3 antibody [EPR8981]

RabMAb|Recombinant

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ATP1B3 antibody [EPR8981] (AB137055)

  • 0
  • 0
Assay Kits

AB211091

MTT Assay Kit (Cell Proliferation)

Functional Studies - MTT Assay Kit (Cell Proliferation) (AB211091)

  • 5
  • 2
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IELISA" : {"fullname" : "Indirect ELISA", "shortname":"I-ELISA"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Enterovirus D68": { "IELISA-species-checked": "predicted", "IELISA-species-dilution-info": "", "IELISA-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Recombinant full length protein - Enterovirus D68": { "IELISA-species-checked": "testedAndGuaranteed", "IELISA-species-dilution-info": "1 µg/mL", "IELISA-species-notes": "<p></p>", "WB-species-checked": "notRecommended", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Transfected cell line - Enterovirus D68": { "IELISA-species-checked": "notRecommended", "IELISA-species-dilution-info": "", "IELISA-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/1000 - 1/5000", "WB-species-notes": "<p></p>" } } }
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제품 세부 정보

Conjugation ready
Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications.

Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
pH: 7 Constituents: PBS, 20% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Enterovirus VP1 also known as viral protein 1 is a structural protein of the enterovirus capsid. It has a mass of approximately 30 kilodaltons and plays an important role in virus assembly and host cell interaction. The protein is expressed on the viral surface and it is responsible for initial binding to the host cell receptors. This interaction facilitates the entry of the virus into cells initiating the infectious cycle. Enterovirus VP1 is highly conserved among different enterovirus serotypes which allows it to serve as a target for diagnostics and therapeutic interventions.
Biological function summary

This protein enables the structural integrity and infectivity of the virus. Enterovirus VP1 is a part of the viral capsid a protein complex that also includes VP2 VP3 and VP4. These proteins collectively protect the viral RNA genome and are involved in mediating interactions with the host immune system. The conformational structure of VP1 is recognized by neutralizing antibodies making it a focus point for vaccine development and antiviral drugs. Its expression and conformation can influence the antigenicity and serotype specificity of enteroviruses.

Pathways

Several actions revolving around host-pathogen interactions involve Enterovirus VP1. It plays a pivotal role in the cell entry mechanism through endocytic pathways. VP1 interacts with proteins such as ICAM-1 or PSGL-1 which serves as receptors in the early stages of viral pathogenesis. Additionally during viral uncoating and RNA release VP1 undergoes structural rearrangements that are essential for subsequent steps in the viral lifecycle and involve complex pathways like the host cell defense mechanism.

Alterations in Enterovirus VP1 are significant in the context of ailments like hand foot and mouth disease and viral myocarditis. The protein's sequence variations can influence disease severity and transmission. Furthermore correlations have been established between the structural aspects of VP1 and host proteins involved in disease manifestation such as cellular kinases influencing viral replication. This protein's interactions and mutations contribute to the pathogenicity and epidemiology of enterovirus-related diseases.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

See full target information Enterovirus D68 VP1 antibody
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Product promise

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