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AB113239

Anti-Eph receptor A6 antibody

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Rabbit Polyclonal Eph receptor A6 antibody. Suitable for IHC-P, ICC/IF and reacts with Human, African green monkey samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human EPHA6 conjugated to Keyhole Limpet Haemocyanin.

대체 명칭 보기

EHK2, HEK12, EPHA6, Ephrin type-A receptor 6, EPH homology kinase 2, EPH-like kinase 12, EHK-2, EK12

3 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Eph receptor A6 antibody (AB113239)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Eph receptor A6 antibody (AB113239)

ab113239, at 10 µg/ml, staining Eph receptor A6 in Formalin-fixed, Paraffin-embedded Human Testis tissue by Immunohistochemistry.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Eph receptor A6 antibody (AB113239)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Eph receptor A6 antibody (AB113239)

ab113239, at 10 µg/ml, staining Eph receptor A6 in Formalin-fixed, Paraffin-embedded Human Brain cerebellum tissue by Immunohistochemistry.

Immunocytochemistry/ Immunofluorescence - Anti-Eph receptor A6 antibody (AB113239)
  • ICC/IF

Unknown

Immunocytochemistry/ Immunofluorescence - Anti-Eph receptor A6 antibody (AB113239)

ab113239, at 1/100 dilution, staining Eph receptor A6 in COS7 cells by Immunofluorescence. The image on the right has been treated with the synthesized peptide.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human, African green monkey

Applications

IHC-P, ICC/IF

applications

Immunogen

Synthetic Peptide within Human EPHA6 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.

Q9UF33

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보완 제품

Proteins & Peptides

AB276886

Recombinant mouse Eph receptor A6 protein (His tag)

Functional Studies - Recombinant mouse Eph receptor A6 protein (His tag) (AB276886)

  • 0
  • 0
Primary Antibodies

AB7046

Anti-Collagen V antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Collagen V antibody (AB7046)

  • 5
  • 11
Primary Antibodies

AB182744

Anti-Collagen VI antibody [EPR17072]

BOND RX™ Validated|20ul selling size|RabMAb|Advanced Validation|Recombinant|KO Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Collagen VI antibody [EPR17072] (AB182744)

  • 4
  • 7
Assay Kits

AB222941

Hydroxyproline Assay Kit (Colorimetric)

Biochemical assay - Hydroxyproline Assay Kit (Colorimetric) (AB222941)

  • 3
  • 4
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "10 µg/mL", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "guaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Mouse": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "African green monkey": { "IHCP-species-checked": "guaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/100 - 1/500", "ICCIF-species-notes": "<p></p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein A
보관 버퍼
pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
보관 정보
Stable for 12 months at -20°C
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Eph receptor A6 also known as EphA6 acts as a receptor tyrosine kinase which belongs to the ephrin receptor subfamily. Its structure involves a mass of approximately 110 kDa. EphA6 is expressed in various tissues with notably high expression in the brain. It plays a mechanical role by binding ephrin ligands which leads to receptor activation and downstream signaling.
Biological function summary

Ephrin-Eph receptor interactions regulate processes like cell adhesion migration and development with EphA6 influencing neural development and plasticity. It does not form a complex on its own but interacts with ephrin ligands to initiate cellular responses. These functions are important for maintaining cellular architecture and communication during development.

Pathways

EphA6 participates in the Ephrin signaling pathway engaging in complex interactions to mediate developmental processes. This receptor also involves itself in the neural development pathway. Proteins like EphA2 and ephrin-A1 frequently interact with EphA6 within these pathways facilitating various signaling cascades that are significant for cellular architecture.

Abnormal expression or function of EphA6 has been associated with neurodegenerative disorders like Alzheimer's disease. Changes in EphA6 participate in disruption of synaptic connections. Within cancer biology EphA6 has been implicated in tumor progression and metastasis. In these contexts it may interact with other proteins such as EGFR influencing cellular behaviors related to malignancy.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity).
See full target information EPHA6
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

International journal of molecular sciences 26: PubMed40332055

2025

A Comparative Study of a Potent CNS-Permeable RARβ-Modulator, Ellorarxine, in Neurons, Glia and Microglia Cells In Vitro.

Applications

Unspecified application

Species

Unspecified reactive species

Yunxi Zhang,Lilie Gailloud,Alexander Shin,Jessica Fewkes,Rosella Pinckney,Andrew Whiting,Paul Chazot
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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