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AB221652

Anti-Ephrin B1 antibody

0

(1 리뷰)

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(1 출판물)

Rabbit Polyclonal Ephrin B1 antibody. Suitable for ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human EFNB1 aa 150-250.

대체 명칭 보기

EFL3, EPLG2, LERK2, EFNB1, Ephrin-B1, EFL-3, ELK ligand, EPH-related receptor tyrosine kinase ligand 2, ELK-L, LERK-2

1 이미지
Immunocytochemistry/ Immunofluorescence - Anti-Ephrin B1 antibody (AB221652)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-Ephrin B1 antibody (AB221652)

PFA-fixed, Triton X-100 permeabilized PC-3 (human prostate adenocarcinoma cell line) cells stained for Ephrin B1 (green) using ab221652 at 4 μg/ml in ICC/IF.

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF

applications

Immunogen

Recombinant Fragment Protein within Human EFNB1 aa 150-250. The exact immunogen used to generate this antibody is proprietary information.

P98172

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보완 제품

Primary Antibodies

AB193634

Anti-Ephrin B2 (phospho Y311) + Ephrin B3 (phospho Y318) + Ephrin B1 (phospho Y324) antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Ephrin B2 (phospho Y311) + Ephrin B3 (phospho Y318) + Ephrin B1 (phospho Y324) antibody (AB193634)

  • 0
  • 0
Primary Antibodies

AB133742

Anti-Eph receptor B3 antibody [EPR8280]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-Eph receptor B3 antibody [EPR8280] (AB133742)

  • 0
  • 0
Primary Antibodies

AB123877

Anti-Ephrin A2 antibody [OTI3E3]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Ephrin A2 antibody [OTI3E3] (AB123877)

  • 0
  • 0
Primary Antibodies

AB307811

Anti-Eph receptor B2 antibody [EPR22422-67]

20ul selling size|RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-Eph receptor B2 antibody [EPR22422-67] (AB307811)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "<p>Fixation/Permeabilization: PFA/Triton X-100.</p>" }, "Mouse": { "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Ephrin-B1 also known as B1 protein or Ephrin-B1 protein is a member of the ephrin family with a mass around 25 kDa. Located on the plasma membrane Ephrin-B1 mainly expresses in the nervous system skeletal system and some epithelial tissues. The protein functions as a ligand for the Eph receptor family which plays a role in cell signaling. Ephrin-B1 interacts with Eph receptors through bi-directional signaling influencing cellular communication and movement.
Biological function summary

Ephrin-B1 is critical for cell positioning and boundary formation. It is part of a transmembrane protein complex influencing cell-to-cell interactions. Through its role in adhesion and repulsion Ephrin-B1 helps coordinate developmental processes such as tissue assembly and organ development. The protein serves essential roles in maintaining cellular architecture ensuring that cells adhere and detach properly during development and wound repair.

Pathways

The ephrin-B1 signaling is important to the Eph receptor pathways particularly the EphB forward and reverse signaling pathways. These pathways are well known for their functions in axon guidance and synaptic plasticity linking Ephrin-B1 with the nervous system development. Related proteins in these pathways include EphB2 and EphB4 which work alongside Ephrin-B1 in regulating the dynamics of these pathways facilitating processes like neurite outgrowth and spine morphogenesis.

Ephrin-B1 is associated with cleft palate and craniofrontonasal syndrome. Mutations or dysregulation in Ephrin-B1 can disrupt normal tissue boundary formation and cell migration leading to such developmental disorders. Abnormal interaction between Ephrin-B1 and related proteins such as EphB2 can affect developmental signaling cascades highlighting the importance of this protein in proper craniofacial and tissue development.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development (PubMed : 7973638, PubMed : 8070404). Binding to Eph receptors residing on adjacent cells leads to contact-dependent bidirectional signaling into neighboring cells (PubMed : 7973638, PubMed : 8070404). Shows high affinity for the receptor tyrosine kinase EPHB1/ELK (PubMed : 7973638, PubMed : 8070404). Can also bind EPHB2 and EPHB3 (PubMed : 8070404). Binds to, and induces collapse of, commissural axons/growth cones in vitro (By similarity). May play a role in constraining the orientation of longitudinally projecting axons (By similarity).
See full target information EFNB1
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

BioMed research international 2024:2973407 PubMed38449509

2024

Identifying G6PC3 as a Potential Key Molecule in Hypoxic Glucose Metabolism of Glioblastoma Derived from the Depiction of F-Fluoromisonidazole and F-Fluorodeoxyglucose Positron Emission Tomography.

Applications

Unspecified application

Species

Unspecified reactive species

Michinari Okamoto,Shigeru Yamaguchi,Ryosuke Sawaya,Sumire Echizenya,Yukitomo Ishi,Sadahiro Kaneko,Hiroaki Motegi,Takuya Toyonaga,Kenji Hirata,Miki Fujimura
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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