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AB236615

Anti-ethanolamine kinase antibody

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(3 제품이 사용된 논문 )

Rabbit Polyclonal ethanolamine kinase antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Fragment Protein within Human ETNK1 aa 50 to C-terminus.

대체 명칭 보기

EKI1, ETNK1, Ethanolamine kinase 1, EKI 1

2 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ethanolamine kinase antibody (AB236615)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ethanolamine kinase antibody (AB236615)

Paraffin-embedded human thyroid tissue stained for ethanolamine kinase with ab236615 at a 1/100 dilution in immunohistochemical analysis.

Immunocytochemistry/ Immunofluorescence - Anti-ethanolamine kinase antibody (AB236615)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-ethanolamine kinase antibody (AB236615)

A549 (Human lung carcinoma cell line) cells stained for ethanolamine kinase (Green) using ab236615 at a 1/100 dilution in ICC/IF. Secondary used is an Alexa-Fluor®488-conjugated Goat Anti-Rabbit IgG (H+L).

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF, WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human ETNK1 aa 50 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q9HBU6

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보완 제품

Primary Antibodies

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Anti-Choline kinase alpha antibody

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Reagents, Controls & Accessories

AB110413

Total OXPHOS Rodent WB Antibody Cocktail

Western blot - Total OXPHOS Rodent WB Antibody Cocktail (AB110413)

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Primary Antibodies

AB183734

Anti-GFP antibody [EPR14104]

RabMAb|Recombinant|Lab Essentials|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GFP antibody [EPR14104] (AB183734)

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Primary Antibodies

AB236405

Anti-PISD antibody [OTI4G5]

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PISD antibody [OTI4G5] (AB236405)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/2000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/20 - 1/200", "IHCP-species-notes": "<p></p>", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "1/50 - 1/200", "ICCIF-species-notes": "<p></p>" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Protein G
Purification 관련 사항
Purity >95%.
보관 버퍼
pH: 7.4 Preservative: 0.03% Proclin 300 Constituents: PBS, 50% Glycerol (glycerin, glycerine)
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Ethanolamine kinase often referred to as ETNK1 is an enzyme known for its role in phospholipid metabolism. It catalyzes the phosphorylation of ethanolamine to produce phosphoethanolamine. This enzyme has a molecular weight of approximately 45 kDa. Ethanolamine kinase is expressed in various tissues including liver and brain indicating its importance in systemic metabolic processes.
Biological function summary

The enzyme is involved in the Kennedy pathway which is responsible for the biosynthesis of phosphatidylethanolamine an important membrane lipid. Ethanolamine kinase operates independently and is not part of any larger protein complex. It supports cellular functions including membrane formation and repair which are critical for proper cell function and signaling.

Pathways

Ethanolamine kinase plays a significant role in the phospholipid biosynthesis pathway and the related glycerophospholipid metabolism pathway. In these pathways it interacts with other enzymes like CTP:phosphoethanolamine cytidylyltransferase shaping the production and regulation of membrane phospholipids. These pathways are essential for maintaining cellular membrane integrity and fluidity.

Ethanolamine kinase has been linked to neurological disorders. Abnormalities in its function can lead to issues in brain phospholipid metabolism potentially contributing to conditions like Alzheimer's disease. Additionally alterations in ethanolamine kinase expression or activity might impact proteins involved in neurodegenerative processes further influencing disease progression.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

Highly specific for ethanolamine phosphorylation. May be a rate-controlling step in phosphatidylethanolamine biosynthesis.
See full target information ETNK1
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제품이 사용된 논문 (3)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Iranian journal of public health 53:208-218 PubMed38694857

2024

MiR-103a-3p Promotes Tumorigenesis of Breast Cancer by Targeting ETNK1.

Applications

Unspecified application

Species

Unspecified reactive species

Lei Li,Aifeng Qiu,Yuhua Shi

BMC cancer 24:534 PubMed38671413

2024

Association of DOK3 and infiltrated tumor-associated macrophages with risk for the prognosis of Porphyromonas gingivalis-infected oral cancer: a 12-year data analysis of 200 patients from a tertiary teaching hospital, Urumqi, China.

Applications

Unspecified application

Species

Unspecified reactive species

Chenxi Li,Muqiu Li,Wei Wei,Zhengye Wang,Jingwen Yu,Zhongcheng Gong

Nature 595:724-729 PubMed34234346

2021

Metabolic control of T cells and humoral immunity by phosphatidylethanolamine.

Applications

Unspecified application

Species

Unspecified reactive species

Guotong Fu,Clifford S Guy,Nicole M Chapman,Gustavo Palacios,Jun Wei,Peipei Zhou,Lingyun Long,Yong-Dong Wang,Chenxi Qian,Yogesh Dhungana,Hongling Huang,Anil Kc,Hao Shi,Sherri Rankin,Scott A Brown,Amanda Johnson,Randall Wakefield,Camenzind G Robinson,Xueyan Liu,Anthony Sheyn,Jiyang Yu,Suzanne Jackowski,Hongbo Chi
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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