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AB236382

Anti-Evx1 antibody [OTI1F8]

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Mouse Monoclonal EVX1 antibody. Suitable for WB and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human EVX1 aa 1-250.

대체 명칭 보기

Homeobox even-skipped homolog protein 1, EVX-1, EVX1

주요 정보

Host species

Mouse

Clonality

Monoclonal

Clone number

OTI1F8

Isotype

IgG1

Carrier free

No

Reacts with

Human

Applications

WB

applications

Immunogen

Recombinant Fragment Protein within Human EVX1 aa 1-250. The exact immunogen used to generate this antibody is proprietary information.

P49640

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대체품

Primary Antibodies

AB220665

Anti-Evx1 antibody

Immunocytochemistry/ Immunofluorescence - Anti-Evx1 antibody (AB220665)

  • 0
  • 0

보완 제품

Primary Antibodies

AB64807

Anti-FOXD3 antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FOXD3 antibody (AB64807)

  • 0
  • 0
Primary Antibodies

AB53281

Anti-Sonic Hedgehog antibody [EP1190Y]

20ul selling size|RabMAb|Recombinant|Trial Size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Sonic Hedgehog antibody [EP1190Y] (AB53281)

  • 5
  • 6
Primary Antibodies

AB16046

Anti-FOXP2 antibody

BOND RX™ Validated

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FOXP2 antibody (AB16046)

  • 5
  • 20
Primary Antibodies

AB221353

Anti-UNCX antibody

Immunocytochemistry/ Immunofluorescence - Anti-UNCX antibody (AB221353)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification
Purification 관련 사항
Purified from cell culture supernatant.
보관 버퍼
pH: 7.3 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 1% BSA
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

Evx1 also known as Even-Skipped Homeobox 1 acts as a transcription factor involved in multiple developmental processes. It belongs to the homeobox gene family and is characterized by a 43 kilodalton mass. Researchers have found Evx1 highly expressed in the embryonic tissue of vertebrates notably in motor neurons and dorsal neural tube regions during early stages of development. Its expression regulates patterns necessary for embryonic morphogenesis and differentiation.
Biological function summary

Evx1 plays a significant role in the regulation of genes essential for embryonic development particularly those involved in neural differentiation and segmentation. This protein interacts with other proteins and forms complexes that modulate gene expression needed for spinal cord development. By influencing the expression of important target genes Evx1 mediates processes important for proper neuronal identity and migration.

Pathways

Evx1 influences several key developmental pathways including the Wnt signaling and Notch signaling pathways. In the Wnt signaling pathway Evx1 interacts with the Wnt proteins to regulate gene transcription and ensure proper pattern formation. Similarly in the Notch signaling pathway Evx1 works alongside Notch proteins contributing to the cell fate decisions and segmental organization. These interactions highlight Evx1's integral role in the precise coordination of embryonic development.

Evx1 has associations with certain developmental abnormalities notably caudal dysgenesis and spina bifida. Such conditions often result from disruptions in normal Evx1 function affecting proper spinal cord formation. The target gene's association with the Wnt and Notch pathways along with proteins like β-catenin and Notch1 links it to these disorders highlighting its importance in maintaining developmental integrity and preventing pathological outcomes.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

May play a role in the specification of neuronal cell types.
See full target information EVX1
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Dose-response : a publication of International Hormesis Society 17:1559325819886766 PubMed31762715

2019

mRNA and lncRNA Expression Profiling of Radiation-Induced Gastric Injury Reveals Potential Radiation-Responsive Transcription Factors.

Applications

Unspecified application

Species

Unspecified reactive species

Guangxia Chen,Yang Feng,Zhiqiang Sun,Yiying Gao,Chuannan Wu,Haihan Zhang,Jinming Cao,Zhuo Chen,Jianping Cao,Yaqun Zhu,Shuyu Zhang
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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