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AB99333

Anti-FAM129B antibody

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Rabbit Polyclonal FAM129B antibody. Suitable for WB and reacts with Human, Mouse samples. Cited in 1 publication. Immunogen corresponding to Synthetic Peptide within Human NIBAN2 aa 650 to C-terminus.
1 이미지
Western blot - Anti-FAM129B antibody (AB99333)
  • WB

Unknown

Western blot - Anti-FAM129B antibody (AB99333)

All lanes:

Western blot - Anti-FAM129B antibody (ab99333) at 0.04 µg/mL

Lane 1:

HeLa whole cell lysate at 50 µg

Lane 2:

HeLa whole cell lysate at 15 µg

Lane 3:

HeLa whole cell lysate at 5 µg

Lane 4:

293T whole cell lysate at 50 µg

Lane 5:

NIH 3T3 whole cell lysate at 50 µg

Predicted band size: 83 kDa

true

Exposure time: 10s

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Mouse, Human

Applications

WB

applications

Immunogen

Synthetic Peptide within Human NIBAN2 aa 650 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

Q96TA1

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대체품

Primary Antibodies

AB224116

Anti-FAM129B antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FAM129B antibody (AB224116)

  • 0
  • 0
Primary Antibodies

AB75638

Anti-FAM129B antibody

Immunocytochemistry/ Immunofluorescence - Anti-FAM129B antibody (AB75638)

  • 0
  • 0

보완 제품

Primary Antibodies

AB72385

Anti-GPR177/WLS antibody

Western blot - Anti-GPR177/WLS antibody (AB72385)

  • 0
  • 0
Primary Antibodies

AB77346

Anti-GPCR TAS1R2 antibody

  • 1
  • 1
Primary Antibodies

AB154804

Anti-PFKM antibody [EPR10734(B)]

RabMAb|Recombinant

Immunocytochemistry/ Immunofluorescence - Anti-PFKM antibody [EPR10734(B)] (AB154804)

  • 5
  • 1
Primary Antibodies

AB223162

Anti-MAGE3 antibody [EPR19065]

RabMAb|Recombinant|20ul selling size

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-MAGE3 antibody [EPR19065] (AB223162)

  • 0
  • 0
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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000 - 1/10000", "WB-species-notes": "<p></p>" }, "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000 - 1/10000", "WB-species-notes": "<p></p>" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Chimpanzee": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Chinese hamster": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Cow": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Dog": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Elephant": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Gorilla": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Horse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Orangutan": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Pig": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Platypus": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rabbit": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" }, "Rhesus monkey": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "" } } }
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특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 6.8 - 7.4 Preservative: 0.09% Sodium azide Constituents: Tris buffered saline, 0.1% BSA
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
+4°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle
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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

FAM129B also known as NIBAN2 functions as a protein implicated in cell survival signaling. It weighs approximately 75 kDa. Expression of FAM129B is detected in various tissues with prominence in the lymphoid tissues and central nervous system. Researchers have highlighted its role in apoptosis regulation where it interacts with other molecules to affect cell fate decisions under stress conditions.
Biological function summary

FAM129B engages in apoptosis modulation and cell survival playing a significant part in cellular stress response. The protein often partners with other components to form complexes that influence intracellular signaling pathways. Specifically by interacting with protein tyrosine phosphatases it affects the delicate balance between survival and programmed cell death providing cells the ability to adapt to fluctuating environmental challenges.

Pathways

FAM129B integrates into the MAPK and PI3K/AKT signaling pathways which are vital for regulating cell survival proliferation and differentiation. Within these pathways FAM129B associates with proteins like AKT and ERK that mediate its impact on cell survival signaling. Its involvement in these pathways suggests a regulatory role in cellular responses to external stimuli contributing to the maintenance of homeostasis.

Abnormal expression or dysfunction of FAM129B links to the pathophysiology of cancers and neurodegenerative diseases. For instance in cancer its interaction with AKT has been implicated in enhancing cell survival potentially leading to tumorigenesis. Additionally the altered regulation of FAM129B has connections to Alzheimer's disease where it may interact with other proteins like tau contributing to neurodegenerative processes.
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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:
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타겟 정보

May play a role in apoptosis suppression. May promote melanoma cell invasion in vitro.
See full target information NIBAN2

대체 명칭 보기

C9orf88, FAM129B, NIBAN2, Protein Niban 2, Meg-3, Melanoma invasion by ERK, Niban-like protein 1, Protein FAM129B, MINERVA
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제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Stem cells translational medicine 11:753-766 PubMed35639962

2022

Heterogeneity of Potassium Channels in Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium.

Applications

Unspecified application

Species

Unspecified reactive species

Iina Korkka,Heli Skottman,Soile Nymark
제품이 사용된 논문 모두 보기
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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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