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AB236383

Anti-FAM131C antibody [OTI6E2]

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Mouse Monoclonal FAM131C antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Full Length Protein corresponding to Human FAM131C.

대체 명칭 보기

C1orf117, FAM131C, Protein FAM131C

3 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FAM131C antibody [OTI6E2] (AB236383)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FAM131C antibody [OTI6E2] (AB236383)

Paraffin-embedded human liver carcinoma tissue stained for FAM131C with ab236383 at 1/500 dilution in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FAM131C antibody [OTI6E2] (AB236383)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FAM131C antibody [OTI6E2] (AB236383)

Paraffin-embedded human pancreas tissue stained for FAM131C with ab236383 at 1/500 dilution in immunohistochemical analysis.

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FAM131C antibody [OTI6E2] (AB236383)
  • IHC-P

Supplier Data

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FAM131C antibody [OTI6E2] (AB236383)

Paraffin-embedded human colon adenocarcinoma tissue stained for FAM131C with ab236383 at 1/500 dilution in immunohistochemical analysis.

주요 정보

Host species

Mouse

Clonality

Monoclonal

Clone number

OTI6E2

Isotype

IgG1

Carrier free

No

Reacts with

Human

Applications

IHC-P, WB

applications

Immunogen

Recombinant Full Length Protein corresponding to Human FAM131C.

Q96AQ9

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/2000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "1/500", "IHCP-species-notes": "<p>Perform heat-induced epitope retrieval by 1 mM EDTA in 10 mM Tris buffer (pH 8.5) at 120°C for 3 minutes.</p>" } } }

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification
Purification 관련 사항
Purified from cell culture supernatant.
보관 버퍼
pH: 7.3 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 1% BSA
배송 시 보관 조건
Blue Ice
적절한 단기 보관 기간
1-2 weeks
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle

추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

The FAM131C protein sometimes referred to simply as a member of the FAM131 protein family shows interesting mechanical functions. With a molecular mass of approximately 30 kDa the FAM131C protein can be detected in several tissues although its expression is particularly noted in the brain and certain immune cells. It often associates with cellular processes that are vital to its mechanical roles.
Biological function summary

The FAM131C protein plays important roles in regulating cellular signaling and communication. As a part of various multiprotein complexes FAM131C interacts with other proteins to modulate immune responses and may influence cell proliferation. This protein shows potential involvement in the modulation of pathways related to cell survival and apoptosis.

Pathways

FAM131C has clear involvement in intracellular signaling pathways. It is associated with the MAPK pathway which is integral to various cellular processes like proliferation and differentiation. FAM131C interacts with proteins such as ERK and MEK contributing to signal transduction mechanisms. Additionally its roles in immune signaling pathways show significant interaction with molecules like NF-kB.

FAM131C has been linked to neurological conditions and certain immunological disorders. Its involvement in processes related to brain function and immune regulation suggests a connection to diseases like Alzheimer's disease and autoimmunity. Further interaction studies highlight connections with proteins such as tau in the context of neurological conditions providing insights into potential therapeutic targets.

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

제품이 사용된 논문 (1)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Dose-response : a publication of International Hormesis Society 17:1559325819886766 PubMed31762715

2019

mRNA and lncRNA Expression Profiling of Radiation-Induced Gastric Injury Reveals Potential Radiation-Responsive Transcription Factors.

Applications

Unspecified application

Species

Unspecified reactive species

Guangxia Chen,Yang Feng,Zhiqiang Sun,Yiying Gao,Chuannan Wu,Haihan Zhang,Jinming Cao,Zhuo Chen,Jianping Cao,Yaqun Zhu,Shuyu Zhang
제품이 사용된 논문 모두 보기

Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.
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