AB204083

Anti-FAM98A antibody

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(4 제품이 사용된 논문 )

Rabbit Polyclonal FAM98A antibody. Suitable for WB, IHC-P, ICC/IF and reacts with Human samples. Cited in 4 publications. Immunogen corresponding to Recombinant Fragment Protein within Human FAM98A aa 1-150.

대체 명칭 보기

Protein FAM98A, FAM98A

3 이미지

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FAM98A antibody (AB204083)

IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FAM98A antibody (AB204083)

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of Human Nasopharynx tissue labelling FAM98A with ab204083 at 1/20 dilution.

Immunocytochemistry/ Immunofluorescence - Anti-FAM98A antibody (AB204083)

ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-FAM98A antibody (AB204083)

Immunofluorescent staining of PFA/Triton X-100 fixed/permeabilized A431 cells labeling FAM98A with ab204083 at 4 μg/ml (green).

Unknown

Western blot - Anti-FAM98A antibody (AB204083)

All lanes:

Western blot - Anti-FAM98A antibody (ab204083) at 0.4 µg/mL

All lanes:

Human cell line HEL

Predicted band size: 55 kDa

false

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

Reacts with

Human

Applications

ICC/IF, WB, IHC-P

applications

Immunogen

Recombinant Fragment Protein within Human FAM98A aa 1-150. The exact immunogen used to generate this antibody is proprietary information.

Q8NCA5

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Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "0.04-0.4 µg/mL", "WB-species-notes": "", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "0.25-2 µg/mL", "ICCIF-species-notes": "" }, "Mouse": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Rat": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" }, "Orangutan": { "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "", "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "" } } }

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특성 및 보관 정보

제형

Liquid

Purification 테크닉

Affinity purification Immunogen

보관 버퍼

pH: 7.2 Preservative: 0.02% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine)

배송 시 보관 조건

Blue Ice

적절한 단기 보관 기간

1-2 weeks

적절한 단기 보관 조건

+4°C

적절한 장기 보관 조건

-20°C

분주 정보

Upon delivery aliquot

보관 정보

Avoid freeze / thaw cycle

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추가 정보

This supplementary information is collated from multiple sources and compiled automatically.

FAM98A also known as Family with Sequence Similarity 98 Member A is a cytoplasmic protein with a mass of approximately 26 kDa. This protein shows expression in various tissues including the brain and liver. It functions mechanically in processes involving RNA contributing to RNA-binding activities although the specific details of its RNA interactions remain to be fully understood.

Biological function summary

This protein acts within a larger multi-protein complex affecting cellular and molecular functions that are important for proper cell regulation. It participates in processes like gene expression modulation although the precise scope of its biological roles is still under investigation. FAM98A also appears to engage in interactions influencing cell cycle regulation which highlights its importance in maintaining cell stability.

Pathways

FAM98A integrates into significant cellular pathways such as TOR signaling and may also influence mitotic processes. It interacts with proteins like the RACK1 scaffolding protein suggesting a role in protein translation and signaling pathways. These interactions position FAM98A within important circuits that oversee cell growth and proliferation.

Changes in FAM98A function or expression could contribute to cancer and neurological disorders reflecting its involvement in cell cycle and regulatory processes. For instance in certain cancers its altered interaction with proteins like RACK1 may impact tumor progression. Meanwhile in neurological disorders disruptions in its RNA-binding role might link to dysregulation of neuronal functions. Further research could open additional insights into these associations.

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제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

Visit the General protocols
Visit the Troubleshooting

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타겟 정보

Positively stimulates PRMT1-induced protein arginine methylation (PubMed : 28040436). Involved in skeletal homeostasis (By similarity). Positively regulates lysosome peripheral distribution and ruffled border formation in osteoclasts (By similarity).

See full target information FAM98A

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제품이 사용된 논문 (4)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Nucleic acids research 53: PubMed40557872

2025

Nonredundant roles of topoisomerase 2α and 2β in the cytosolic replication of vaccinia virus.

Applications

Unspecified application

Species

Unspecified reactive species

Ilaria Dalla Rosa,Lois Kent,Michael Way

Journal of gynecologic oncology 33:e2 PubMed34783205

2021

Circular RNA intraflagellar transport 80 facilitates endometrial cancer progression through modulating miR-545-3p/FAM98A signaling.

Applications

Unspecified application

Species

Unspecified reactive species

Na Wang,Yunfeng Guo,Liqin Song,Tong Tong,Xiaomei Fan

Oncology letters 21:367 PubMed33747224

2021

MicroRNA-26a inhibits cell proliferation and invasion by targeting FAM98A in breast cancer.

Applications

Unspecified application

Species

Unspecified reactive species

Tan Liu,Ziming Wang,Menghao Dong,Jingjing Wei,Yueyin Pan

Cancer management and research 10:2269-2278 PubMed30100758

2018

FAM98A promotes proliferation of non-small cell lung cancer cells via the P38-ATF2 signaling pathway.

Applications

Unspecified application

Species

Unspecified reactive species

Rui Zheng,Quanbo Liu,Tianxu Wang,Lili Wang,Yong Zhang

제품이 사용된 논문 모두 보기

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Product promise

저희는 고품질 시약으로 고객님의 연구를 서포트하고자 최선을 다하고 있으며, 모든 단계에서 함께 하겠습니다. 만약 제품이 기대한 성능을 보이지 않을 경우에도 Product Promise로 보호받으실 수 있습니다.

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Please note: All products are 'FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES'.

For licensing inquiries, please contact partnerships@abcam.com

Anti-FAM98A antibody

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FAM98A antibody (AB204083)

Immunocytochemistry/ Immunofluorescence - Anti-FAM98A antibody (AB204083)

Western blot - Anti-FAM98A antibody (AB204083)

주요 정보

Host species

Clonality

Isotype

Carrier free

Reacts with

Applications

Immunogen

보완 제품

Primary Antibodies

Primary Antibodies

Primary Antibodies

Primary Antibodies

Reactivity 정보

특성 및 보관 정보

제형

Purification 테크닉

보관 버퍼

배송 시 보관 조건

적절한 단기 보관 기간

적절한 단기 보관 조건

적절한 장기 보관 조건

분주 정보

보관 정보

추가 정보

Biological function summary

Pathways

제품 프로토콜

타겟 정보

제품이 사용된 논문 (4)

Product promise