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AB151986

Anti-FcRgamma antibody

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(5 제품이 사용된 논문 )

Rabbit Polyclonal FcRgamma antibody. Suitable for ICC/IF, WB, IHC-P and reacts with Human, Recombinant fragment samples. Cited in 5 publications. Immunogen corresponding to Synthetic Peptide within Human FCER1G aa 1 to C-terminus.

대체 명칭 보기

High affinity immunoglobulin epsilon receptor subunit gamma, Fc receptor gamma-chain, Fc-epsilon RI-gamma, IgE Fc receptor subunit gamma, FcRgamma, FceRI gamma, FCER1G

3 이미지
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FcRgamma antibody (AB151986)
  • IHC-P

Unknown

Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-FcRgamma antibody (AB151986)

Immunohistochemical analysis of paraffin-embedded U873 xenograft tissue labeling FcRgamma with ab151986 at 1/100 dilution.

Immunocytochemistry/ Immunofluorescence - Anti-FcRgamma antibody (AB151986)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-FcRgamma antibody (AB151986)

Immunofluorescence analysis of HepG2 cells fixed in 4% paraformaldehyde at RT for 15 min labelling FCER1G protein at cell membrane using ab151986 at a 1/500 dilution (Green). alpha Tubulin, a cytoskeleton marker, stained by alpha Tubulin antibody [GT114] at a 1/1000 dilution (Red). DAPI was used for nuclear staining (Blue).
Scale bar= 10 µm.

Immunocytochemistry/ Immunofluorescence - Anti-FcRgamma antibody (AB151986)
  • ICC/IF

Supplier Data

Immunocytochemistry/ Immunofluorescence - Anti-FcRgamma antibody (AB151986)

Immunofluorescence analysis of THP-1 cells fixed in 4% paraformaldehyde at RT for 15 min labelling FCER1G protein at cytoplasm using ab151986 at a 1/500 dilution (Green). DAPI was used for nuclear staining (Blue).

주요 정보

Host species

Rabbit

Clonality

Polyclonal

Isotype

IgG

Carrier free

No

Reacts with

Human

Applications

ICC/IF, IHC-P, WB

applications

Immunogen

Synthetic Peptide within Human FCER1G aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.

P30273

Reactivity 정보

{ "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "IHCP" : {"fullname" : "Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)", "shortname":"IHC-P"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Human": { "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "<p></p>", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "testedAndGuaranteed", "IHCP-species-dilution-info": "", "IHCP-species-notes": "<p>Perform heat mediated antigen retrieval before commencing with IHC staining protocol using 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0).</p>" }, "Rat": { "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Dog": { "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Pig": { "ICCIF-species-checked": "predicted", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "WB-species-checked": "predicted", "WB-species-dilution-info": "", "WB-species-notes": "", "IHCP-species-checked": "predicted", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" }, "Recombinant fragment": { "ICCIF-species-checked": "notRecommended", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "", "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "1/500 - 1/3000", "WB-species-notes": "<p></p>", "IHCP-species-checked": "notRecommended", "IHCP-species-dilution-info": "", "IHCP-species-notes": "" } } }

특성 및 보관 정보

제형
Liquid
Purification 테크닉
Affinity purification Immunogen
보관 버퍼
pH: 7 Preservative: 0.01% Thimerosal (merthiolate) Constituents: 10% Glycerol (glycerin, glycerine), 1.21% Tris, 0.75% Glycine
배송 시 보관 조건
Blue Ice
적절한 단기 보관 조건
+4°C
적절한 장기 보관 조건
-20°C
분주 정보
Upon delivery aliquot
보관 정보
Avoid freeze / thaw cycle

제품 프로토콜

For this product, it's our understanding that no specific protocols are required. You can visit:

타겟 정보

Adapter protein containing an immunoreceptor tyrosine-based activation motif (ITAM) that transduces activation signals from various immunoreceptors. As a component of the high-affinity immunoglobulin E (IgE) receptor, mediates allergic inflammatory signaling in mast cells. As a constitutive component of interleukin-3 receptor complex, selectively mediates interleukin 4/IL4 production by basophils, priming T-cells toward effector T-helper 2 subset. Associates with pattern recognition receptors CLEC4D and CLEC4E to form a functional signaling complex in myeloid cells. Binding of mycobacterial trehalose 6,6'-dimycolate (TDM) to this receptor complex leads to phosphorylation of ITAM, triggering activation of SYK, CARD9 and NF-kappa-B, consequently driving maturation of antigen-presenting cells and shaping antigen-specific priming of T-cells toward effector T-helper 1 and T-helper 17 cell subtypes. May function cooperatively with other activating receptors. Functionally linked to integrin beta-2/ITGB2-mediated neutrophil activation. Also involved in integrin alpha-2/ITGA2-mediated platelet activation.
See full target information FCER1G

제품이 사용된 논문 (5)

Recent publications for all applications. Explore the 전체 목록 and refine your search

Journal for immunotherapy of cancer 13: PubMed39755578

2025

Spatial and single-cell transcriptomics reveal cellular heterogeneity and a novel cancer-promoting Treg cell subset in human clear-cell renal cell carcinoma.

Applications

Unspecified application

Species

Unspecified reactive species

Xiyu Song,Yumeng Zhu,Wenwen Geng,Jianhua Jiao,Hongjiao Liu,Ruo Chen,Qian He,Lijuan Wang,Xiuxuan Sun,Weijun Qin,Jiejie Geng,Zhinan Chen

Cell reports 42:113413 PubMed38096059

2023

Synonymous codon usage regulates translation initiation.

Applications

Unspecified application

Species

Unspecified reactive species

Chloe L Barrington,Gabriel Galindo,Amanda L Koch,Emma R Horton,Evan J Morrison,Samantha Tisa,Timothy J Stasevich,Olivia S Rissland

Advanced science (Weinheim, Baden-Wurttemberg, Germany) 10:e2205397 PubMed36727833

2023

Neuronal C-Reactive Protein/FcγRI Positive Feedback Proinflammatory Signaling Contributes to Nerve Injury Induced Neuropathic Pain.

Applications

Unspecified application

Species

Unspecified reactive species

Fan Liu,Li Zhang,Si Su,Yehong Fang,Xiang-Sha Yin,Huan Cui,Jianru Sun,Yikuan Xie,Chao Ma

BMC cancer 22:140 PubMed35120484

2022

FCER1G positively relates to macrophage infiltration in clear cell renal cell carcinoma and contributes to unfavorable prognosis by regulating tumor immunity.

Applications

Unspecified application

Species

Unspecified reactive species

Keqin Dong,Wenjin Chen,Xiuwu Pan,Hongru Wang,Ye Sun,Cheng Qian,Weijie Chen,Chao Wang,Fu Yang,Xingang Cui

Cancer cell international 21:103 PubMed33579299

2021

Prognostic and predictive value of FCER1G in glioma outcomes and response to immunotherapy.

Applications

Unspecified application

Species

Unspecified reactive species

Houshi Xu,Qingwei Zhu,Lan Tang,Junkun Jiang,Huiwen Yuan,Anke Zhang,Meiqing Lou
제품이 사용된 논문 모두 보기

Product promise

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